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J Pak Med Assoc ; 60(8): 653-6, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20726197

ABSTRACT

OBJECTIVE: To analyze the pattern of dyslipidaemias including apolipoprotein B in type 2 diabetes. METHODS: A total of 120 diabetics were studied for their lipid profile including serum triglycerides, total cholesterol, HDL cholesterol and LDL cholesterol in fasting state, along with apolipoprotein B levels. RESULTS: Raised apolipoprotein B was the most frequent lipid disorder in type 2 diabetics, occurring in 56.7% of the studied patients. This was followed by high serum triglycerides levels in 55.8% and low HDL cholesterol levels in 55% of patients. Notably, 6% patients had normal triglyceride levels accompanied by raised LDL cholesterol, compared to 20% patients who had normal triglycerides with high apolipoprotein B levels. Overall, 36% of patients had normal LDL cholesterol values but elevated apolipoprotein B. CONCLUSION: Apolipoprotein B is the most frequently occurring dyslipidaemia in type 2 diabetes. It identifies individuals with high risk of coronary heart disease not otherwise detected on routine lipid profile.


Subject(s)
Apolipoproteins B/blood , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Diabetes Mellitus, Type 2/blood , Triglycerides/blood , Adult , Aged , Body Mass Index , Cross-Sectional Studies , Diabetes Mellitus, Type 2/complications , Dyslipidemias/epidemiology , Female , Humans , Male , Middle Aged , Pakistan/epidemiology , Risk Factors , Sex Factors
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