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1.
Pharm Nanotechnol ; 2024 May 20.
Article in English | MEDLINE | ID: mdl-38778594

ABSTRACT

Cancer nanomedicine has the potential to take advantage of the multifunctionality and diverse biological activity of nanostructures based on biomolecules. Novel drug delivery vehicles can be designed by programming the supramolecular features of biomolecules to achieve multiple therapeutic goals at once, including efficient in vivo transport and targeted drug administration. Proteins, peptides, nucleic acids, and polysaccharides can all be engineered into multipurpose nanomedicines. Even while numerous cancer medications reduce mortality, they are still insufficient. Early cancer cell detection and high-specificity therapeutic administration optimise treatment and prevent toxicity. Nanotechnology is improving cancer diagnosis and treatment due to increased systemic toxicity and refractoriness with current methods. Nanotechnology-based immunotherapeutic drugs have reduced cancer cell invasiveness while protecting healthy cells in several cancer types. Carbon nanotubes, polymeric micelles, and liposomes improve cancer medication pharmacokinetics and pharmacodynamics. Nanomedicines' use in patient care and promising nanotechnology-based cancer interventions have been covered in this article. Nanomaterials used in treating cancer have been discussed. Additionally, nanomaterial obstacles that hinder their applicability and clinical translation in certain cancer types are addressed.

2.
Healthc Manage Forum ; 35(5): 310-317, 2022 Sep.
Article in English | MEDLINE | ID: mdl-35830436

ABSTRACT

Enhancing the use of technology in long-term care has been identified as a key part of broader efforts to strengthen the sector in the wake of the COVID-19 pandemic. To inform such efforts, we convened a series of citizen panels, followed by a national stakeholder dialogue with system leaders focused on reimagining the long-term care sector using technology. Key actions prioritized through the deliberations convened included: developing an innovation roadmap/agenda (including national standards and guidelines); using co-design approaches for the strengthening the long-term care sector and for technological innovation; identifying and coordinating existing innovation projects to support scale and spread; enabling rapid-learning and improvement cycles to support the development, evaluation, and implementation of new technologies; and using funding models that enable the flexibility needed for such rapid-learning cycles.


Subject(s)
COVID-19 , Long-Term Care/methods , Stakeholder Participation , Technology/methods , Canada , Humans , Long-Term Care/trends , Pandemics , Technology/trends
3.
Hamilton; McMaster Health Forum; Sept. 27, 2019. 28 p. (McMaster Health Forum).
Monography in English | PIE | ID: biblio-1052880

ABSTRACT

Prenatal education has expanded significantly over the past two decades, from its initial conception as an opportunity to teach pain management in labour and preparation for birth in the hospital environment to including broader public-health principles of preparing women and their families for pregnancy, labour and birth, care of the newborn and the adjustments to life as a family.(1) It also provides an opportunity to assist women in detecting warning signs in pregnancy, build confidence in self-care, and can act as an opportunity for early intervention in high-risk pregnancies.


Subject(s)
Humans , Female , Pregnancy , Prenatal Education/methods , Prenatal Education/statistics & numerical data , Evaluation of Results of Preventive Actions/methods
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