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1.
Int J Surg Case Rep ; 81: 105835, 2021 Apr.
Article in English | MEDLINE | ID: mdl-33887831

ABSTRACT

INTRODUCTION AND IMPORTANCE: Idiopathic spontaneous intraperitoneal hemorrhage (ISIH) is a rare but potentially fatal entity. The majority of the reported cases of ISIH due to middle colic artery rupture are associated with pseudoaneurysm. Our case is unique in that no pathology could be identified. To our knowledge, this is the third case report in the literature of a spontaneous middle colic artery rupture with no underlying pathology. CASE PRESENTATION: In our report, we present the case of a 27-years old male presenting with a hemoperitoneum due to ruptured middle colic artery with no evidence of pseudoaneurysm or any other pathology. The patient's hemodynamic status deteriorated abruptly requiring a damage control exploratory laparotomy for evacuation of the hemoperitoneum, ligation of the middle colic artery and transverse colectomy. The post-operative course was uneventful afterwards and the patient was discharged a week after presentation with full recovery. DISCUSSION: Patients with ISIH might exhibit the "double rupture" phenomenon, compromising their hemodynamic stability and necessitating urgent surgical interventions. CTA can be of paramount importance to guide such interventions if the patient's clinical status permits. Angiographic embolization is an acceptable alternative approach in specific situations. CONCLUSION: ISIH should be on the differential diagnosis of any young patient presenting to the ED with an acute abdomen, regardless of the identifiable risk factors.

3.
Obes Surg ; 29(12): 3800-3808, 2019 12.
Article in English | MEDLINE | ID: mdl-31286397

ABSTRACT

BACKGROUND: Dexmedetomidine is an α2 receptor agonist with sedative and analgesic properties. During bariatric surgery, its use may reduce postoperative opioid requirements, reduce their side effects, and improve quality of recovery. The aim of this prospective randomized controlled trial was to compare the effect of dexmedetomidine bolus and infusion versus morphine bolus given prior to the end of laparoscopic bariatric surgery. METHODS: Sixty morbidly obese patients (BMI > 40 kg m-2) aged 18 to 60 years, undergoing laparoscopic sleeve gastrectomy, received morphine sulfate (bolus 0.08 mg kg-1 followed by a saline infusion) (group M, n = 30) or dexmedetomidine (loading dose of 1 µg kg-1 followed by 0.5 µg kg-1 h-1) (group D, n = 30) 30 min before the end of surgery. Data collected included morphine consumption in the post-anesthesia care unit (PACU) (primary outcome) and at 24 h, pain intensity, nausea, heart rate, blood pressure, vomiting, sedation, and quality of recovery. RESULTS: There was no significant difference in morphine consumption in the PACU (group D 12.2 ± 5.44 mg, group M 13.28 ± 6.64 mg, P = 0.54) or at 24 h (group D 40.67 ± 24.78 mg, group M 43.28 ± 27.79 mg, P = 0.75); when accounting for intraoperative morphine given group M had significantly higher morphine consumption when compared to group D (23.48 ± 6.22 mg vs. 12.22 ± 5.54 mg, respectively, P < 0.01). Group D patients had more cardiovascular stability. CONCLUSIONS: Dexmedetomidine given prior to end of laparoscopic sleeve gastrectomy provides the same level of postoperative analgesia as morphine with better hemodynamic profile.


Subject(s)
Bariatric Surgery/adverse effects , Dexmedetomidine/administration & dosage , Intraoperative Care/methods , Morphine/administration & dosage , Obesity, Morbid/surgery , Pain, Postoperative/drug therapy , Adolescent , Adult , Analgesics/administration & dosage , Analgesics/adverse effects , Analgesics, Non-Narcotic/administration & dosage , Analgesics, Opioid/administration & dosage , Analgesics, Opioid/adverse effects , Anesthesia Recovery Period , Bariatric Surgery/methods , Bariatric Surgery/statistics & numerical data , Dexmedetomidine/adverse effects , Dose-Response Relationship, Drug , Double-Blind Method , Female , Humans , Hypnotics and Sedatives/administration & dosage , Hypnotics and Sedatives/adverse effects , Laparoscopy/adverse effects , Laparoscopy/methods , Lebanon/epidemiology , Male , Middle Aged , Morphine/adverse effects , Obesity, Morbid/epidemiology , Pain, Postoperative/epidemiology , Young Adult
4.
Surg Endosc ; 33(11): 3629-3634, 2019 11.
Article in English | MEDLINE | ID: mdl-30706152

ABSTRACT

BACKGROUND: Intraoperative endoscopy (IOE) has been proposed to decrease serious complications following bariatric surgeries such as leaks, bleeding, and stenosis. Such complications can lead to sepsis and eventually can be fatal. We aim to compare major postoperative complications in patients with and without IOE. METHODS: Data from the American College of Surgeons National Surgical Quality Improvement Program database years 2011 till 2016 were used to identify laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) patients. We compared outcomes of IOE and non-IOE using bivariate and multivariate analysis. Thirty-day outcomes included sepsis, organ space infection, unplanned reoperations, unplanned readmissions, prolonged hospital stay, bleeding, and mortality. RESULTS: Out of 62,805 cases of LSG and 50,047 cases of LRYGB, 17.9%, and 19.7% had IOE, respectively. Endoscopy-assisted LSG was associated with a decrease in sepsis [0.37% vs. 0.21%, adjusted odds ratio (AOR) = 0.55 (0.36, 0.84)], unplanned reoperation [0.58% vs. 0.38%, AOR = 0.61 (0.44, 0.85)], prolonged hospital stay [14.9% vs. 14.0%, AOR = 0.87 (0.82, 0.92)], and composite complications [1.43% vs. 1.17%, AOR = 0.78 (0.65, 0.94)]. Outcomes after LRYGB were similar in both groups, except for decreased prolonged hospital stay with IOE [22.4% vs. 20.6%, AOR = 0.89 (0.84, 0.94)]. CONCLUSIONS: IOE is generally underutilized in baraitric procedures. IOE is associated with decreased risk of postoperative complications particularly sepsis, unplanned reoperations, prolonged hospital stay, and composite complications after LSG; and hospital stay after LRYGB. Large multicenter prospective studies are needed to explore the benefits of IOE in bariatric surgery, particularly the intermediate or long-term benefits.


Subject(s)
Bariatric Surgery/methods , Intraoperative Complications/epidemiology , Laparoscopy/methods , Obesity, Morbid/surgery , Postoperative Complications/epidemiology , Quality Improvement , Adult , Databases, Factual , Female , Humans , Incidence , Length of Stay , Male , Prospective Studies , Reoperation , United States/epidemiology
5.
Surg Obes Relat Dis ; 14(10): 1463-1470, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30449508

ABSTRACT

BACKGROUND: Laparoscopic sleeve gastrectomy (SG) has become the most popular bariatric operation over the last decade. Extreme obesity and increasing age have been generally associated with higher risks of complications after bariatric surgery. The postoperative risk for complications after SG has not been previously presented according to simultaneous grouping of body mass index (BMI) and age. OBJECTIVE: We aim to explore the association of age and BMI in determining the postoperative risk of SG from a national perspective. SETTING: The American College of Surgeons National Surgical Quality Improvement Program database. METHODS: We analyzed patient characteristics and operative outcomes of the 2010 to 2013 SG cohort available in the American College of Surgeons National Surgical Quality Improvement Program (N = 21,131). Patients were grouped based on age and BMI: young-obese (N = 10,291; <50 yr, BMI <0 kg/m2; reference group), young-super-obese (N = 3594; <50 yr and BMI ≥50 kg/m2), older-obese (N = 5636; ≥50 yr, BMI <0 kg/m2), and older-super-obese (N = 1610; ≥50 yr, BMI ≥50 kg/m2). Composite morbidity and/or mortality (M&M) was used as the primary outcome and risk-adjusted odds ratios (AOR[M&M]) were derived by logistic regression. M&M was a composite of surgical site, renal, neurologic, cardiac, thromboembolic, respiratory, septic and bleeding complications, unplanned readmissions, prolonged stay, and death. RESULTS: Overall operative mortality was low (.1%) but significantly worse in older-super-obese patients (.37%; P = .005). M&M rates were lowest in young-obese (5.8%), similarly worse in young-super-obese (7.0%) and older-obese (7.0%), and highest for older-super-obese (10.1%; P < .001). After comprehensive covariate risk adjustment, the composite M&M outcome after SG was significantly increased (42%) only in older-super-obese patients (AOR = 1.42 [1.16-1.73]), while older age alone (AOR = 1.09 [.94-1.25]) and super obesity alone (AOR = 1.09 [.93-1.28]) did not. CONCLUSIONS: Analysis of the American College of Surgeons National Surgical Quality Improvement Program showed that super obesity is associated with increased complications in older patients undergoing SG. Older-super-obese patients should be appropriately counseled about increased SG perioperative risks within the context of expected long-term benefits.


Subject(s)
Bariatric Surgery/adverse effects , Gastrectomy/adverse effects , Laparoscopy/adverse effects , Obesity, Morbid/surgery , Age Factors , Aged , Ambulatory Surgical Procedures/statistics & numerical data , Bariatric Surgery/mortality , Body Mass Index , Female , Gastrectomy/mortality , Hospitalization/statistics & numerical data , Humans , Laparoscopy/mortality , Male , Middle Aged , Obesity, Morbid/mortality , Postoperative Complications/etiology , Prospective Studies , Quality Improvement , United States/epidemiology
6.
Obes Surg ; 28(9): 2852, 2018 Sep.
Article in English | MEDLINE | ID: mdl-29761262

ABSTRACT

The authors regret that some of the article text, which was in the original manuscript and was intended for and addressed to the reviewers during the review process of this article, was mistakenly overlooked during the proofs stage and remains in the published article.

7.
Obes Surg ; 28(9): 2844-2851, 2018 09.
Article in English | MEDLINE | ID: mdl-29696572

ABSTRACT

INTRODUCTION: Chronic liver disease is prevalent in obese patients presenting for bariatric surgery and is associated with increased postoperative morbidity and mortality (M&M). There are no comparative studies on the safety of different types of bariatric operations in this subset of patients. OBJECTIVE: The aim of this study is to compare the 30-day postoperative M&M between laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-Y-gastric bypass (LRYGB) in the subset of patients with a model of end-stage liver disease (MELD) score ≥ 8. METHODS: Data for LSG and LRYGB were extracted from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from years 2012 and 2013. MELD score was calculated using serum creatinine, bilirubin, INR, and sodium. Postoperative M&M were assessed in patients with a score ≥ 8 and compared for the type of operation. This was followed by analysis for MELD subcategories. Multiple logistic regression was performed to adjust for confounders. RESULTS: Out of 34,169, 9.8% of cases had MELD ≥ 8 and were included. Primary endpoint, 30-day M&M, was significantly lower post-LSG (9.5%) compared to LRYGB (14.7%); [AOR = 0.66(0.53, 0.83)]. Superficial wound infection, prolonged hospital stay, and unplanned readmission were more common in LRYGB. M&M post-LRYGB (30.6%) was significantly higher than LSG (15.7%) among MELD15-19 subgroup analysis. CONCLUSION: LRYGB is associated with a higher postoperative risk than LSG in patients with MELD ≥ 8. The difference in postoperative complications between procedures was magnified with higher MELD. This suggests that LSG might be a safer option in morbidly obese patients with higher MELD scores, especially above 15.


Subject(s)
Gastrectomy/adverse effects , Gastrectomy/mortality , Gastric Bypass/adverse effects , Gastric Bypass/mortality , Liver Diseases/epidemiology , Obesity, Morbid/epidemiology , Obesity, Morbid/surgery , Adult , Databases, Factual , Female , Gastrectomy/methods , Gastrectomy/statistics & numerical data , Gastric Bypass/methods , Gastric Bypass/statistics & numerical data , Humans , Laparoscopy/adverse effects , Laparoscopy/methods , Laparoscopy/mortality , Laparoscopy/statistics & numerical data , Length of Stay/statistics & numerical data , Liver Diseases/etiology , Liver Diseases/mortality , Male , Middle Aged , Morbidity , Mortality , National Health Programs/organization & administration , National Health Programs/standards , Obesity, Morbid/complications , Obesity, Morbid/mortality , Patient Readmission/statistics & numerical data , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Postoperative Complications/mortality , Prevalence , Quality Improvement/organization & administration , Quality Improvement/standards , Risk Factors , Surgeons/organization & administration , Surgeons/standards , Time Factors , United States/epidemiology
9.
Obes Surg ; 27(11): 2898-2904, 2017 11.
Article in English | MEDLINE | ID: mdl-28455802

ABSTRACT

PURPOSE: The effectiveness of the concomitant repair of hiatal hernia (HHR) during laparoscopic sleeve gastrectomy (LSG) in reducing gastroesophageal reflux disease (GERD) symptoms is still unclear. The aim of this study is to assess the effect of concomitant HHR on postoperative GERD symptoms in our patient population. MATERIALS AND METHODS: A retrospective review of patients who underwent LSG with or without HHR between 2011and 2014 was performed. Pre- and postoperative GERD symptoms were assessed at different time intervals until a maximum of 2 years after the surgery. RESULTS: The study included 165 patients; 76 (46%) underwent LSG with concomitant HHR (group A) while the rest underwent only LSG (group B). Baseline GERD complaints were more prevalent in group A (61.8 vs 41.6%, p = 0.04), in which 44 patients (57.9%) had evidence of hiatal hernia on preoperative EGD. In the remaining 32 patients, it was diagnosed intraoperatively. GERD symptoms did not significantly differ between the two groups after years 1 and 2. GERD remission was observed in 21.3% of the 76 patients who underwent concomitant HHR (group A) and in 29.7% of those who did not (group B) while new-onset GERD symptoms were reported in 12 patients (41.4%) in group A and in 24 patients (46.2%) in group B. CONCLUSIONS: Routine HHR at the time of LSG does not show an improvement in GERD symptoms. More prospective studies are needed to clarify the role of the routine dissection, identification, and repair of concomitant hiatal hernia during LSG.


Subject(s)
Gastrectomy/adverse effects , Gastroesophageal Reflux/etiology , Hernia, Hiatal/surgery , Herniorrhaphy/adverse effects , Obesity, Morbid/surgery , Adult , Female , Gastrectomy/methods , Gastroesophageal Reflux/epidemiology , Hernia, Hiatal/complications , Hernia, Hiatal/epidemiology , Herniorrhaphy/methods , Herniorrhaphy/statistics & numerical data , Humans , Laparoscopy/adverse effects , Laparoscopy/methods , Laparoscopy/statistics & numerical data , Male , Middle Aged , Obesity, Morbid/complications , Obesity, Morbid/epidemiology , Prevalence , Prospective Studies , Retrospective Studies , Treatment Outcome
10.
Obes Surg ; 27(6): 1401-1408, 2017 06.
Article in English | MEDLINE | ID: mdl-28108969

ABSTRACT

BACKGROUND: Laparoscopic adjustable gastric band (LAGB) carries a high rate of failure and reoperation. Laparoscopic conversion of failed LAGB to Roux-en-Y gastric bypass (RYGB) has been shown to be safe and feasible, but long-term follow-up data is still limited. OBJECTIVES: The aim of this study is to evaluate the safety and effectiveness of RYGB after failed LAGB in our patient population. SETTING: The setting was the University Hospital, Beirut, Lebanon. METHODS: Using a prospectively collected database, we retrospectively reviewed data of patients who underwent LAGB revision to RYGB at our institution between 2006 and 2014. RESULTS: A total of 58 patients underwent RYGB after failed LAGB in our institution between 2006 and 2014. Of those, 20 patients (34.5%) had concomitant band removal while the rest underwent a two-stage RYGB after a mean of 30 months after band removal. A follow-up was achieved in 84.5, 82, 83, 95, and 76% of patients at 1, 2, 3, 4, and 5 years after RYGB. Percentage of excess weight loss (%EWL) was 62.8, 68.1, 64.2, 63.8, and 61.3% at 1, 2, 3, 4, and 5 years, respectively, while percentage of total weight loss (%TWL) was 28.4, 30.7, 29.4, 28.9, and 28.6% at the corresponding time periods. The most common short-term complications were abscesses/leaks (5.2%) while the most common long-term complications were symptomatic gallstones necessitating laparoscopic cholecystectomy (5.2%), incisional hernias (5.2%), and small-bowel obstruction (3.4%). No surgery-related mortality was recorded. CONCLUSIONS: RYGB is a safe procedure with favorable weight loss outcomes at 5 years and can be considered a good rescue procedure after failed LAGB.


Subject(s)
Conversion to Open Surgery , Gastric Bypass/statistics & numerical data , Obesity, Morbid/surgery , Adolescent , Adult , Aged , Body Mass Index , Databases, Factual , Female , Gastroplasty/adverse effects , Humans , Incisional Hernia/surgery , Laparoscopy/adverse effects , Lebanon , Male , Middle Aged , Obesity, Morbid/mortality , Retrospective Studies , Treatment Outcome , Young Adult
11.
Obes Surg ; 27(2): 462-468, 2017 02.
Article in English | MEDLINE | ID: mdl-27592125

ABSTRACT

BACKGROUND: Conversion of laparoscopic adjustable gastric banding (LGB) to laparoscopic Roux-en-Y gastric bypass (LRYGB) is an established procedure. However, multiple reports have indicated higher morbidity and mortality rates associated with this operation, especially when performed as a single-staged procedure. PURPOSE: We sought to compare mortality and morbidity of LRYGB vs. LRYGB with concomitant gastric band removal (LRYGB/LGBR). METHODS: Data from the American College of Surgeons' National Surgical Quality Improvement Program (ACS-NSQIP) database was obtained for the time period of 2008 to 2014 using CPT codes for LRYGB and LGBR. Sepsis was the primary outcome measure with overall morbidity as a secondary outcome. Bivariate and multivariate analyses were carried out using SAS (Statistical Analysis System). RESULTS: During the study period, 64,866 patients had primary LRYGB and 1212 had LRYGB/LGBR. On bivariate analyses, mean operative time was lower for patients undergoing LRYGB rather than LRYGB/LGBR (132.88 ± 56.29 vs. 177.72 ± 70.21 min, p < 0.001). There was no statistically significant difference in the rate of postoperative mortality (0.16 vs. 0.08 %, p > 0.999), sepsis (0.78 vs. 0.74 %, p = 0.87), or other postoperative outcomes such as return to the operating room, wound infection, and venous thromboembolism. The odds ratio (OR) for sepsis remained not significant (OR = 0.74; 95 % confidence interval (CI) = (0.38-1.45)) after multivariate analysis. CONCLUSION: LRYGBP/LGBR is not associated with a higher morbidity and mortality compared to LRYGB alone. The data implies that a one-step revisional procedure is appropriate when converting a failed gastric band to LRYGB.


Subject(s)
Bariatric Surgery , Gastric Bypass , Postoperative Complications/epidemiology , Bariatric Surgery/adverse effects , Bariatric Surgery/methods , Bariatric Surgery/statistics & numerical data , Gastric Bypass/adverse effects , Gastric Bypass/methods , Gastric Bypass/statistics & numerical data , Humans , Laparoscopy , Obesity, Morbid/surgery , Treatment Outcome
12.
Surg Obes Relat Dis ; 12(7): 1300-1304, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27178610

ABSTRACT

BACKGROUND: Patients with morbid obesity are at a higher risk of developing gallstones after bariatric surgery. Studies on the incidence of symptomatic gallstones necessitating cholecystectomy after laparoscopic sleeve gastrectomy (LSG) are limited in the Middle East. OBJECTIVES: This study aims to assess the incidence of cholecystectomy after LSG during a 1-year follow-up and to evaluate potential risk factors and potential prophylactic measures. SETTING: Two university hospitals in Lebanon. METHODS: A prospectively maintained bariatric database of 361 patients who underwent primary LSG between January 2009 and December 2012 at the American University of Beirut Medical Center and Makassed General Hospital was reviewed. Data included demographics, preoperative weight, weight at 6 and 12 months postoperatively, and incidence of postoperative symptomatic cholelithiasis. RESULTS: A total of 319 patients (88.4%) were followed up at 1 year. Twenty-four (7.5%) had symptomatic gallstones and underwent cholecystectomy after LSG. Mean postoperative time for the development of symptomatic gallstones was 426 days (range, 91-1234 days). Patients who developed symptomatic gallstones were significantly younger (29.8 versus 34.8, P = 0.008) but comparable to patients who did not undergo cholecystectomy in terms of other baseline characteristics and weight loss results at 1 year. Out of the obesity-related co-morbidities, hypertension was the only co-morbidity associated with post-LSG cholecystectomy (OR = 3.35, P = 0.036) after multivariate adjustment. CONCLUSION: The incidence of symptomatic gallstones requiring cholecystectomy after LSG in our study cohort was higher than that of the general population (7.5%). This incidence does not warrant prophylactic cholecystectomy or routine pre- or postoperative ultrasounds.


Subject(s)
Bariatric Surgery/adverse effects , Gallstones/surgery , Gastrectomy/adverse effects , Laparoscopy/adverse effects , Adult , Cholecystectomy/methods , Female , Gallstones/epidemiology , Gallstones/etiology , Humans , Incidence , Lebanon/epidemiology , Male , Obesity, Morbid/epidemiology , Obesity, Morbid/surgery , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Postoperative Complications/surgery , Retrospective Studies , Risk Factors
13.
Surg Obes Relat Dis ; 12(5): 984-988, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27134199

ABSTRACT

BACKGROUND: Conversion of adjustable gastric band to laparoscopic sleeve gastrectomy (LSG) is feasible, but multiple reports have indicated higher morbidity and staple line leak rates when this is performed as a single-stage procedure. The objective of this study is to compare the safety profile and outcomes of LSG with concomitant gastric band removal (LSG/GBR) versus LSG using the American College of Surgeons' National Surgical Quality Improvement Program (ACS-NSQIP). METHODS: Using the ACS-NSQIP database (2010-2012), LSG cases were identified using Current Procedural Terminology (CPT) code 43775 and concomitant LSG/LGBR using CPT code 43775+(43772 or 43774). Baseline patient characteristics and perioperative variables including postoperative mortality and morbidity rates were retrieved. The primary endpoint was sepsis within 30 days. Bivariate and multivariate analyses were carried out. RESULTS: During the study period, 11,189 (96.9%) patients had LSG and 357 (3.1%) had LSG/GBR for a total of 11,546 patients. On bivariate analyses, the rate of sepsis was higher after LSG/GBR (1.68% versus .58%; P = .022), and the mean operative time was longer (124.6±52.3 versus 98.6±49.0 min; P<.001). There was no statistically significant difference in the rate of postoperative mortality (.28% versus .08 %; P = .27) or that of other outcomes such as return to the operating room, wound infection, or venous thromboembolism. After multivariate analysis, the odds of developing postoperative sepsis remained significantly higher for patients undergoing LSG/GBR compared with LSG alone (odds ratio [OR] 3.32; confidence interval [CI] 1.41-7.84; P = .006). CONCLUSION: LSG/GBR can be performed with low morbidity and mortality. However, this procedure carries a higher rate of postoperative sepsis.


Subject(s)
Gastrectomy/methods , Gastroplasty/methods , Laparoscopy/methods , Adult , Aged , Device Removal/adverse effects , Device Removal/methods , Female , Gastrectomy/adverse effects , Gastrectomy/mortality , Gastroplasty/adverse effects , Gastroplasty/mortality , Humans , Laparoscopy/adverse effects , Male , Middle Aged , Obesity/mortality , Obesity/surgery , Operative Time , Postoperative Complications/etiology , Postoperative Complications/mortality , Prospective Studies , Reoperation , Sepsis/etiology , Sepsis/mortality , Treatment Outcome
14.
Surg Obes Relat Dis ; 12(2): 405-11, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26775049

ABSTRACT

BACKGROUND: Vitamin D deficiency is common among obese patients presenting for bariatric surgery in Europe and North America. The prevalence of vitamin D deficiency in this patient population in Lebanon and the Middle East has not been studied. OBJECTIVES: The aim of this study was to determine the rate of vitamin D deficiency in a cohort of patients presenting for bariatric surgery in Lebanon. SETTING: American University of Beirut Medical Center, Beirut, Lebanon. METHODS: Data was extracted from a prospective database of patients presenting for bariatric surgery at the American University of Beirut Medical Center from July 2011 until June 2014. The prevalence of vitamin D deficiency was determined using established cut-offs followed by analysis of the relationship between low vitamin D and certain patient characteristics. RESULTS: More than two thirds of all patients (68.9%) were vitamin D deficient (≤19.9 ng/mL), whereas 22.6% had insufficient levels (20-29.9 ng/mL) and only 8.6 % had sufficient levels (≥30 ng/mL). Vitamin D levels were inversely associated with BMI>50 kg/m(2). Low vitamin D levels were also correlated with younger age, male gender, lack of physical exercise, and nonsunny season. No association was shown between 25-hydroxyvitamin D deficiency and type 2 diabetes mellitus, cardiovascular disease, osteoarticular disease, hypertension, or depression. CONCLUSION: Vitamin D deficiency is prevalent among patients with Class II or Class III obesity presenting for bariatric surgery in Lebanon. These findings emphasize the need for careful attention when evaluating patients before bariatric surgery and the importance of providing patients with adequate supplementation.


Subject(s)
Bariatric Surgery , Obesity, Morbid/complications , Vitamin D Deficiency/epidemiology , Vitamin D/analogs & derivatives , Adolescent , Adult , Aged , Female , Follow-Up Studies , Humans , Lebanon/epidemiology , Male , Middle Aged , Obesity, Morbid/surgery , Prevalence , Retrospective Studies , Vitamin D/blood , Vitamin D Deficiency/blood , Vitamin D Deficiency/etiology , Young Adult
15.
Surg Obes Relat Dis ; 11(5): 1037-43, 2015.
Article in English | MEDLINE | ID: mdl-26143296

ABSTRACT

BACKGROUND: Sleeve gastrectomy (SG) has become a widely adopted bariatric surgical procedure. The most serious complication is staple line leak (SLL), which is potentially life threatening and, in some patients, becomes chronic and difficult to manage. Definitive surgical management of SLL is effective but seldom published in the literature. OBJECTIVES: This study aims to review the outcome of definitive surgical management of SLL after SG, looking at short-term and long-term results. SETTING: Single surgeon experience based at a tertiary university hospital in Beirut, Lebanon. METHODS: Retrospective review of records of patients with SLL who underwent definitive surgical treatment by the senior author (B.Y.S.) from January 2008 until December 2013. RESULTS: Ten patients (50% female) underwent definitive surgical repair during the study period. The mean age, weight, and body mass index at the time of SG were 35 years, 121 kg, and 41.5 kg/m(2), respectively. Most leaks (90%) were at the esophagogastric junction. All underwent multiple operative, endoscopic, or radiologic procedures before definitive surgical repair. Methods of definitive repair included open Roux-en-Y (RY) esophagojejunostomy (70%), open RY gastric bypass (10%), laparoscopic RY esophagojejunostomy (10%), and one laparoscopic RY fistulojejunostomy (10%). Six patients (60%) underwent definitive surgical treatment because of chronic SLL, on average, 26 weeks after leak detection (range 13-39 wk). The other 4 underwent repair earlier, on average 4 weeks after leak detection (1-7 wk). There were no mortalities, and all patients healed without residual leak. Perioperative morbidity developed in 1 of 6 (17%) patients who underwent delayed repair and in 75% of patients who underwent repair early. Patients who underwent early repair were heavier (body mass index 40.5 kg/m(2) versus 30 kg/m(2)) and nutritionally more deplete (albumin 26.7 g/L versus 39.2 g/L). All patients are well at a mean follow-up of 21.6 months (7.5-55.9 mo) with an average percentage excess weight loss of 74% (57%-120%). CONCLUSIONS: Definitive surgical management of SLL was uniformly effective with acceptable morbidity. It is indicated in patients with chronic persistent fistula beyond 12 weeks, provided patients are kept in good nutritional state. Some select patients may benefit from this approach in the early phases, but the surgical risks are higher.


Subject(s)
Anastomotic Leak/surgery , Gastrectomy/adverse effects , Laparoscopy/adverse effects , Obesity, Morbid/surgery , Surgical Stapling/adverse effects , Adult , Anastomotic Leak/etiology , Bariatric Surgery/adverse effects , Bariatric Surgery/methods , Body Mass Index , Cohort Studies , Female , Follow-Up Studies , Gastrectomy/methods , Hospitals, University , Humans , Laparoscopy/methods , Lebanon , Male , Middle Aged , Obesity, Morbid/diagnosis , Postoperative Complications/diagnosis , Postoperative Complications/surgery , Reoperation/methods , Retrospective Studies , Risk Assessment , Surgical Stapling/methods , Time Factors , Treatment Outcome , Young Adult
17.
Surg Obes Relat Dis ; 10(1): 106-10, 2014.
Article in English | MEDLINE | ID: mdl-24342033

ABSTRACT

BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is thought to be a simpler and safer operation compared with malabsorptive operations that include an enteric anastomosis. Leakage along the staple line at the gastroesophageal junction (GEJ) is difficult to treat and is a known complication of sleeve gastrectomy. Nonsurgical treatment methods often fail to heal the leaks and patients often require conversion to other procedures for definitive treatment. We report our experience with conversion to Roux-en-Y anastomosis over the leak site as a treatment option, comparing patients who had early treatment to late intervention. The purpose of the study is to stress the medical and social benefits of early surgical reintervention with conversion to Roux-en-Y anastomosis over the leak site. METHODS: Six patients underwent Roux limb placement over the leak site. Four of the patients had delayed surgery (group A), and the other 2 had early intervention (group B). RESULTS: Patients in group A had a median increase of all medical cost by 500%, whereas the 2 patients who underwent early intervention (group B) had an increase by 200%. The mean time until complete recovery (removal of all drains, adequate oral intake, and return to normal daily activity) in group A was 131.25 days (range 99-165) versus 38 days (range 28-48) in group B. CONCLUSIONS: Roux-en-Y gastrojejunostomy over the leak site is an effective technique to treat refractory staple line leakage and can be adopted as early treatment in selected patients after stabilization, thereby reducing the cost and length of hospital stays.


Subject(s)
Anastomotic Leak/surgery , Gastrectomy/adverse effects , Obesity, Morbid/surgery , Adult , Anastomosis, Roux-en-Y/methods , Anastomotic Leak/etiology , Esophagogastric Junction/surgery , Female , Humans , Middle Aged , Reoperation , Surgical Stapling/adverse effects , Young Adult
18.
Surg Obes Relat Dis ; 3(2): 141-5; discussion 145-6, 2007.
Article in English | MEDLINE | ID: mdl-17331803

ABSTRACT

BACKGROUND: Roux-en-Y gastric bypass surgery is the leading surgical treatment of morbid obesity in the United States. The role of preoperative weight loss in gastric bypass surgery remains controversial. We performed a prospective randomized trial to determine whether preoperative weight loss results in better outcomes after laparoscopic gastric bypass. METHODS: A total of 100 patients undergoing laparoscopic gastric bypass surgery from May 2004 to October 2005 were randomized preoperatively to either a weight loss group with a 10% weight loss requirement or a group that had no weight loss requirements. The patients were followed prospectively. The variables analyzed included perioperative complications, operative time, postoperative weight loss, and resolution of co-morbidities. RESULTS: Data were available for 26 patients in the weight loss group and 35 in the nonweight loss group. The 2 groups had similar preoperative characteristics, conversion and complication rates, and resolution of co-morbidities. The initial body mass index was 48.7 kg/m(2) and 49.3 kg/m(2) for the weight loss group and nonweight loss group, respectively (P = NS). The preoperative body mass index was 44.5 kg/m(2) and 50.7 kg/m(2) for the weight loss group and nonweight loss group, respectively (P = 0.0027). The operative time was 220.2 and 257.6 minutes for the 2 groups (P = 0.0084). The percentage of excess weight loss at 3 and 6 months for the weight loss group and nonweight loss group was 44.1% and 33.1% (P = 0.0267) and 53.9% and 50.9% (P = NS), respectively. The interval to surgery from the initial consultation was 5.4 months and 5.2 months for the 2 groups (P = NS). CONCLUSIONS: Preoperative weight loss before laparoscopic Roux-en-Y gastric bypass was associated with a decrease in the operating room time and an improved percentage of excess weight loss in the short term. Preoperative weight loss, however, did not affect the major complication or conversion rates, and its long-term effects were not apparent through this study. Also, preoperative weight loss did not have any bearing on the resolution of co-morbidities.


Subject(s)
Gastric Bypass/methods , Obesity, Morbid/surgery , Preoperative Care/methods , Weight Loss , Adult , Body Mass Index , Female , Follow-Up Studies , Humans , Laparoscopy , Male , Postoperative Complications/prevention & control , Prospective Studies , Risk Factors , Treatment Outcome
19.
Obes Surg ; 16(11): 1464-8, 2006 Nov.
Article in English | MEDLINE | ID: mdl-17132412

ABSTRACT

BACKGROUND: Obesity and associated co-morbidities have become an epidemic in the United States. As surgery for obesity becomes more common, surgical training programs need to address this growing demand. We conducted this study to assess prospective surgery trainees' attitudes and knowledge regarding surgery for morbid obesity. METHODS: An anonymous and voluntary questionnaire was given to prospective surgical residency applicants to complete during their interview. The questionnaire included basic demographic information and addressed the applicants' attitudes and basic knowledge about surgery for obesity. RESULTS: 57 applicants to the surgical residency program completed the survey. Demographic information included: 51% male, 36% from the Northeast, 32% with obese family members, and 93% applying for a categorical surgery position. 81% of applicants had been exposed to bariatric surgery. Although 70% of applicants would perform bariatric surgery as part of their practice, only 44% would make this their career. Reasons for reluctance to treat bariatric surgery patients included: more complications (46%), non-compliant patients (33%), and technically demanding surgery (18%). 89% responded that they would recommend bariatric surgery to a family member, but only 77% would consider it for themselves. Overall correct answers regarding bariatric surgery knowledge were 74%. CONCLUSIONS: Attitudes and knowledge about surgery for morbid obesity were generally positive in prospective surgical trainees. Medical school curriculum and surgical training programs should continue to expose trainees to information from this ever-growing field.


Subject(s)
Attitude of Health Personnel , Bariatric Surgery , General Surgery/education , Internship and Residency , Obesity, Morbid/surgery , Students, Medical/psychology , Clinical Competence , Female , Humans , Male , Treatment Outcome
20.
Obes Surg ; 16(9): 1205-8, 2006 Sep.
Article in English | MEDLINE | ID: mdl-16989705

ABSTRACT

BACKGROUND: Many patients seeking surgical treatment for morbid obesity present with anterior abdominal wall hernias. Although principles of hernia repair involve a tension-free repair with the use of prosthetic mesh, there is concern about the use of mesh in gastric bypass surgery due to potential contamination with the contents of the gastrointestinal tract and resultant mesh infection. We report our series of patients undergoing Roux-en-Y gastric bypass (RYGBP) and simultaneous anterior abdominal wall hernia repair. METHODS: All patients who underwent simultaneous RYGBP surgery and anterior abdominal wall hernia repair were reviewed. RESULTS: 12 patients underwent concurrent RYGBP and anterior wall hernia repair. There were 5 women and 7 men with average age 54.9 +/- 8.5 years (range 35 to 64) and average body mass index (BMI) 50.4 +/- 10.3 kg/m(2) (range 38 to 70). Two open and 10 laparoscopic RYGBP operations were performed. Nine patients (75%) underwent incisional hernia repairs and 3 patients (25%) underwent umbilical hernia repair concurrent with gastric bypass. Average size of defect was 14.7 +/- 13.4 cm(2). One patient had primary repair and 11 patients had prosthetic mesh repair: polypropylene in 3 patients (25%) and polyester in 8 patients (67%). With a 14.1 +/- 9.3 month follow-up, there have been no mesh infections and 2 recurrences, one in the patient who underwent primary repair and one in a patient repaired with polyester mesh but with two previous failed incisional hernia repairs. CONCLUSION: Concurrent RYGBP and repair of anterior abdominal wall hernias is safe and feasible. In order to optimize success, tension-free principles of hernia repair with the use of prosthetic mesh should be followed since no mesh infections occurred in our series.


Subject(s)
Gastric Bypass , Hernia, Abdominal/complications , Hernia, Abdominal/surgery , Laparoscopy , Obesity, Morbid/complications , Obesity, Morbid/surgery , Adult , Body Mass Index , Female , Humans , Male , Middle Aged , Retrospective Studies , Surgical Mesh , Suture Techniques , Treatment Outcome
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