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1.
Cir Pediatr ; 34(3): 156-159, 2021 Jul 01.
Article in English, Spanish | MEDLINE | ID: mdl-34254756

ABSTRACT

INTRODUCTION: Gastric heterotopy is a rare entity in the pediatric population. It occurs in the gastrointestinal tract, leading to digestive bleeding. CLINICAL CASE: This is the case of a 10-year-old boy with gastric tissue in the proximal jejunum, which caused two massive digestive bleeding episodes. Diagnostic techniques included endoscopic capsule, enteroscopy, and biopsy. The patient was scheduled for laparotomy and resection. After one year of follow-up, he remained asymptomatic. DISCUSSION: Gastric heterotopy approach represents a diagnostic challenge. Owing to how rare it is, there is no global consensus in terms of treatment. However, surgery is the definitive therapy. In this case, decision was made not to perform intestinal resection and anastomosis, but resection of the compromised intestinal wall. No malignity was reported in the literature reviewed.


INTRODUCCION: La heterotopia gástrica es una entidad infrecuente en la población pediátrica. Se presenta en el tracto gastrointestinal llevando a cuadros clínicos de sangrado digestivo. CASO CLINICO: Se reporta el caso de un escolar de 10 años, el cual presentó tejido gástrico en el yeyuno proximal, originando sangrado digestivo masivo en dos ocasiones. La secuencia de apoyos diagnósticos requirió cápsula endoscópica, enteroscopia y biopsia. Fue llevado a laparotomía y resección de la lesión. En el seguimiento al año se mantuvo asintomático. DISCUSION: Su abordaje genera un reto diagnóstico. Debido a su infrecuente presentación no hay un consenso global para el tratamiento, sin embargo, la intervención quirúrgica es la terapia definitiva. En este caso no se hizo resección intestinal y anastomosis sino resección de la pared intestinal comprometida. No se reportó malignidad en la literatura revisada.


Subject(s)
Gastrointestinal Hemorrhage , Laparoscopy , Anastomosis, Surgical , Biopsy , Child , Gastrointestinal Hemorrhage/diagnosis , Gastrointestinal Hemorrhage/etiology , Gastrointestinal Hemorrhage/surgery , Humans , Jejunum , Male
2.
Cir. pediátr ; 34(3): 156-159, Jul. 2021. ilus
Article in Spanish | IBECS | ID: ibc-216760

ABSTRACT

Introducción: La heterotopia gástrica es una entidad infrecuente enla población pediátrica. Se presenta en el tracto gastrointestinal llevandoa cuadros clínicos de sangrado digestivo. Caso clínico: Se reporta el caso de un escolar de 10 años, el cualpresentó tejido gástrico en el yeyuno proximal, originando sangradodigestivo masivo en dos ocasiones. La secuencia de apoyos diagnósti-cos requirió cápsula endoscópica, enteroscopia y biopsia. Fue llevadoa laparotomía y resección de la lesión. En el seguimiento al año semantuvo asintomático. Discusión: Su abordaje genera un reto diagnóstico. Debido a suinfrecuente presentación no hay un consenso global para el tratamien-to, sin embargo, la intervención quirúrgica es la terapia definitiva. Eneste caso no se hizo resección intestinal y anastomosis sino resecciónde la pared intestinal comprometida. No se reportó malignidad en laliteratura revisada.(AU)


Introduction: Gastric heterotopy is a rare entity in the pediatricpopulation. It occurs in the gastrointestinal tract, leading to digestivebleeding. Clinical case: This is the case of a 10-year-old boy with gastrictissue in the proximal jejunum, which caused two massive digestivebleeding episodes. Diagnostic techniques included endoscopic capsule,enteroscopy, and biopsy. The patient was scheduled for laparotomyand resection. After one year of follow-up, he remained asymptomatic. Discussion: Gastric heterotopy approach represents a diagnosticchallenge. Owing to how rare it is, there is no global consensus in termsof treatment. However, surgery is the definitive therapy. In this case,decision was made not to perform intestinal resection and anastomosis,but resection of the compromised intestinal wall. No malignity wasreported in the literature reviewed.(AU)


Subject(s)
Humans , Male , Child , Jejunum , Gastric Mucosa , Gastrointestinal Hemorrhage , Gastrointestinal Tract/injuries , Pediatrics , General Surgery
3.
Horm Metab Res ; 13(2): 107-9, 1981 Feb.
Article in English | MEDLINE | ID: mdl-6785179

ABSTRACT

Synthetic beta-(pyrazolyl-1)-alanine-2-TRH, an analog of thyrotropin releasing hormone (TRH) was administered intravenously in doses of 50, 100 and 200 micrograms to four normal men in order to establish the range of responses of TSH and prolactin. Every subject showed a clear elevation in TSH and prolactin levels with all three doses. These results were compared with the increments in TSH and prolactin after the administration of the same doses of synthetic TRH. The computations of potency for absolute levels and/or increments in TSH and prolactin at 20 and 40 min showed that the analog was at least twice as active as TRH in releasing TSH and prolactin.


Subject(s)
Prolactin/metabolism , Thyrotropin-Releasing Hormone/analogs & derivatives , Thyrotropin/metabolism , Adult , Dose-Response Relationship, Drug , Humans , Kinetics , Male
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