[Study of the dynamics of human serum albumin by coherent Rayleigh dispersion of Mossbauer radiation]. / Izuchenie dinamiki syvorotochnogo al'bumina cheloveka metodom kogerentnogo réleevskogo rasseianiia Messbauérovskogo izlucheniia.

The measurements of angle dependencies of total and elastic Rayleigh scattering of Mossbauer radiation intensities have been performed for human serum albumin (HSA) with hydration degrees h = 0.13 and h = 0.4. The extended model was developed for calculating the inelastic intensity of Rayleigh scattering. Original data for HSA and published data on met-Mb were fitted within the frame of this model. The best agreement with experiment was obtained when two types of intraglobular motions were taken into account: individual motions of small side-chain groups and cooperative (mechanical) motions of segments (most probable alpha-helices). Long-range correlated motions are essential at low hydration degree. The possibilities of application of the coherent version of RSMS technique are described.