ABSTRACT
The purpose of this study was to evaluate the effect of docosahexaenoic acid (DHA) dietary supplementation on semen quality, fatty acid composition, antioxidant capacity, and DNA fragmentation. In this randomized, double blind, placebo-controlled, parallel-group study, 74 subjects were recruited and randomly assigned to either the placebo group (n=32) or to the DHA group (n=42) to consume three 500-mg capsules of oil per day over 10 weeks. The placebo group received 1,500 mg/day of sunflower oil and the DHA group 1,500 mg/day of DHA-enriched oil. Seminal parameters (semen volume, sperm concentration, motility, morphology, and vitality), total antioxidant capacity, deoxyribonucleic acid fragmentation, and lipid composition were evaluated prior to the treatment and after 10 weeks. Finally, 57 subjects were included in the study with 25 in the placebo group and 32 in the DHA group. No differences were found in traditional sperm parameters or lipid composition of the sperm membrane after treatment. However, an increase in DHA and Omega-3 fatty acid content in seminal plasma, an improvement in antioxidant status, and a reduction in the percentage of spermatozoa with deoxyribonucleic acid damage were observed in the DHA group after 10 weeks of treatment.
Subject(s)
Antioxidants/metabolism , DNA Fragmentation , Dietary Supplements , Docosahexaenoic Acids/administration & dosage , Semen/metabolism , Spermatozoa/metabolism , Double-Blind Method , Humans , Lipid Metabolism , Male , PlacebosABSTRACT
In recent years, image techniques have transformed the diagnosis in Medicine. Nevertheless, they are, by now, far from a widespread clinic and surgical use. Beyond the simple picture inspection, DICOM digital files can be explored by using image analysis/processing techniques in a better way. In practice, clinicians and surgeons usually are limited to 'see' pictures delivered by Radiology. However, image analysis/processing techniques allow the 'client' (neurologist or neuro-surgeon) to accomplish interactive image visualizations, multiplanar or 3D rendering, measurements, pathway visualizations, etc. All these tasks, offer a great advantage in diagnosis, surgical planning, teaching and investigation. This paper revise the fundaments of image analysis techniques in order to emphasize their utility, and to widespread its utilization not in the server (Radiological Department) but, principally, in the client side. Some examples of cranio-spinal pathologies are presented aiming to these objectives.
Subject(s)
Diagnostic Imaging/methods , Image Processing, Computer-Assisted/methods , Neurology/methods , Neurosurgery/methods , Neurosurgical Procedures/methods , Humans , Radiology/methods , User-Computer InterfaceABSTRACT
Resumen. Las técnicas de diagnóstico por imagen han revolucionado los métodos de detección de enfermedades. Sin embargo, su plena utilización en el ámbito clínico y quirúrgico está lejos de alcanzarse. Más allá de la mera inspección de la imagen, los ficheros digitales pueden explorarse mediante técnicas de análisis y proceso de imagen de una manera muy eficaz. Considerado como un sistema cliente-servidor, el cliente (neurólogo o neurocirujano) sólo puede, habitualmente, visualizar las imágenes suministradas desde el servicio de radiodiagnóstico. Las técnicas de análisis y proceso de imagen, sin embargo, empleadas en el área cliente, permiten visualizaciones interactivas, reconstrucciones, mediciones y otras tareas de gran ayuda en el diagnóstico, planificación operatoria, docencia e investigación. El presente trabajo persigue revisar las bases de estas técnicas, enfatizar su utilidad y extender su empleo no en el lado servidor (radiodiagnóstico), sino en el cliente. Estos procedimientos resultan de especial utilidad en neurociencia. Se analizan diversos ejemplos procedentes de la patología craneoespinal con este objetivo (AU)
Summary. In recent years, image techniques have transformed the diagnosis in Medicine. Nevertheless, they are, by now, far from a widespread clinic and surgical use. Beyond the simple picture inspection, DICOM digital files can be explored by using image analysis/processing techniques in a better way. In practice, clinicians and surgeons usually are limited to see pictures delivered by Radiology. However, image analysis/processing techniques allow the client (neurologist or neurosurgeon) to accomplish interactive image visualizations, multiplanar or 3D rendering, measurements, pathway visualizations, etc. All these tasks, offer a great advantage in diagnosis, surgical planning, teaching and investigation. This paper revise the fundaments of image analysis techniques in order to emphasize their utility, and to widespread its utilization not in the server (Radiological Department) but, principally, in the client side. Some examples of cranio-spinal pathologies are presented aiming to these objectives (AU)
