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1.
Am J Transplant ; 24(1): 104-114, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37666457

ABSTRACT

Face transplantation is a viable reconstructive approach for severe craniofacial defects. Despite the evolution witnessed in the field, ethical aspects, clinical and psychosocial implications, public perception, and economic sustainability remain the subject of debate and unanswered questions. Furthermore, poor data reporting and sharing, the absence of standardized metrics for outcome evaluation, and the lack of consensus definitions of success and failure have hampered the development of a "transplantation culture" on a global scale. We completed a 2-round online modified Delphi process with 35 international face transplant stakeholders, including surgeons, clinicians, psychologists, psychiatrists, ethicists, policymakers, and researchers, with a representation of 10 of the 19 face transplant teams that had already performed the procedure and 73% of face transplants. Themes addressed included patient assessment and selection, indications, social support networks, clinical framework, surgical considerations, data on patient progress and outcomes, definitions of success and failure, public image and perception, and financial sustainability. The presented recommendations are the product of a shared commitment of face transplant teams to foster the development of face transplantation and are aimed at providing a gold standard of practice and policy.


Subject(s)
Facial Transplantation , Vascularized Composite Allotransplantation , Humans , Facial Transplantation/methods , Consensus , Delphi Technique , Research Design
2.
J Hist Med Allied Sci ; 76(3): 319-345, 2021 Sep 06.
Article in English | MEDLINE | ID: mdl-34179990

ABSTRACT

Face transplants have attracted global media and public attention since the 1990s. The first recipient, Isabelle Dinoire, found herself at the centre of a dramatic episode of surgical innovation after her transplant was announced in November 2005. Subsequently 47 transplants have been conducted worldwide (including two retransplants) up to August 2020, and these have been accompanied by extensive news coverage. Hundreds of papers on the medical, physical, psychological, and ethical implications of the procedure have been published in the scientific literature, disproportionate to the incidence of the procedure. Face transplants have also featured in films, television, and fiction, indicating an appetite for interrogating the social and interpersonal implications of facial difference. However, the history of facial transplantation has largely been unexplored. This article provides the first international history of the global development and implementation of facial transplantation. Using published medical literature, media coverage, and oral history interviews with key participants as source material, it situates the experimental transplant in national, institutional, and professional contexts. It argues that charting the history of face transplants over a 30 year period from initial discussions in 1991 to the present provides a valuable case study through which to consider surgical cultures and discourses of medical innovation in the twenty-first century.


Subject(s)
Facial Transplantation/history , Facial Transplantation/methods , Facial Transplantation/statistics & numerical data , History, 20th Century , History, 21st Century , Humans
3.
Lancet ; 395(10230): 1106-1107, 2020 04 04.
Article in English | MEDLINE | ID: mdl-32247387
5.
Isis ; 100(4): 798-810, 2009 Dec.
Article in English | MEDLINE | ID: mdl-20380348

ABSTRACT

The histories of emotion address many fundamental themes of science and medicine. These include the ways the body and its workings have been historically observed and measured, the rise of the mind sciences, and the anthropological analyses by which "ways of knowing" are culturally situated. Yet such histories bring their own challenges, not least in how historians of science and medicine view the relationship between bodies, minds, and emotions. This essay explores some of the methodological challenges of emotion history, using the sudden death of the surgeon John Hunter from cardiac disease as a case study. It argues that we need to let go of many of our modem assumptions about the origin of emotions, and "brainhood", that dominate discussions of identity, in order to explore the historical meanings of emotions as products of the body as well as the mind.


Subject(s)
Emotions , Philosophy/history , Psychology/history , Social Perception , Stress, Psychological , England , General Surgery/history , Heart Diseases/history , History, 18th Century , Humans , Male
7.
Lancet ; 371(9621): 1329, 2008 Apr 19.
Article in English | MEDLINE | ID: mdl-18424314
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