[Multimodality treatment outcome of invasive thymomas]. / Rezultatele tratamentului multimodal în timoame.

UNLABELLED: The aim of the study was to analyze the progression of invasive thymomas associated with myasthenia gravis, after the resection and the progression of unresectable invasive thymomas with a combined chemoradiotherapy. The study was performed on two groups of patients: 8 patients with invasive thymomas and myasthenia gravis operated at the 3rd Surgical Clinic between 1986-1999; 4 patients with unresectable invasive thymomas treated at the Radiology-Oncology Clinic by combined chemoradiotherapy, between 1993-1998. The results are presented for each group of patients, separately. CONCLUSION: The best treatment of invasive thymomas is the multimodal one. The timing of each method was established based on the collaboration between surgeons, medical oncologists, radiotherapists and neurologists, depending on the characteristics of each patient.

[A practical study of the absorbed doses at the level of the organs at risk during the radiotherapy of bronchopulmonary cancer]. / Studiul practic al dozelor absorbite la nivelul organelor de risc, în cursul radioterapiei cancerului bronhopulmonar.

The radiotherapy of lung cancer with curative total doses (56-60 Gy), is limited by the presence of critical organs (esophagus, spinal cord). The use of computed TPS (Therapy Planning System) allows to the radiotherapist to calculate the values and to obtain dose distribution to the organs at risk, in the limit of biological tolerance levels. In our work, we present the calculation of the absorbed doses of Co60, at the spinal cord, at a patient with a cancer of the right lung, during irradiation.

[The use of hyperfractionated radiotherapy in soft-tissue sarcomas]. / Utilizarea radioterapiei hiperfractionate în sarcoamele de parti moi.

In classical irradiation, the local control can be negatively influenced by the accelerated clonogenic tumoral repopulation. A modality of control of this phenomenon can be accelerated hyperfractionated irradiation. The aim of this paper is the study of the effect of this type of irradiation in soft tissue sarcomas on patients of the Radiological-Oncological Clinic Iasi. Accelerated hyperfractionated irradiation causes a favorable response in the primary tumor with good local tolerance, but the "free of disease" period depends on the aim of irradiation (preoperative, postoperative or single therapeutical procedure).

[Radiotherapy concomitant with cisplatin chemotherapy in the treatment of cancer of the cervix uteri]. / Radioterapie concomitent cu chimioterapie cu cisplatin în tratamentul cancerului de col uterin.

Cancer of the cervix presents an increasing incidence and mortality in advanced stages. Failure of treatment consists in local recurrence, continuation of evolution or in distant metastasis. One of the strategies of improving the treatment response is the association of radiosensitization chemotherapy with irradiation. The aim of this paper is the study of the effect of cisplatin administration simultaneously with radiotherapy of primary cancer of the cervix and recurrences. This association has proved to be favourable as regards immediate and short period local control with an acceptable digestive and hematologic tolerance (gr. I-II).