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1.
Phys Life Rev ; 48: 132-161, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38219370

ABSTRACT

This survey provides a comprehensive insight into the world of non-invasive brain stimulation and focuses on the evolving landscape of deep brain stimulation through microwave research. Non-invasive brain stimulation techniques provide new prospects for comprehending and treating neurological disorders. We investigate the methods shaping the future of deep brain stimulation, emphasizing the role of microwave technology in this transformative journey. Specifically, we explore antenna structures and optimization strategies to enhance the efficiency of high-frequency microwave stimulation. These advancements can potentially revolutionize the field by providing a safer and more precise means of modulating neural activity. Furthermore, we address the challenges that researchers currently face in the realm of microwave brain stimulation. From safety concerns to methodological intricacies, this survey outlines the barriers that must be overcome to fully unlock the potential of this technology. This survey serves as a roadmap for advancing research in microwave brain stimulation, pointing out potential directions and innovations that promise to reshape the field.


Subject(s)
Microwaves , Nervous System Diseases , Humans , Stereotaxic Techniques , Technology , Brain/physiology
2.
Article in English | MEDLINE | ID: mdl-38051611

ABSTRACT

Emotion is a complex physiological and psychological activity, accompanied by subjective physiological sensations and objective physiological changes. The body sensation map describes the changes in body sensation associated with emotion in a topographic manner, but it relies on subjective evaluations from participants. Physiological signals are a more reliable measure of emotion, but most research focuses on the central nervous system, neglecting the importance of the peripheral nervous system. In this study, a body surface potential mapping (BSPM) system was constructed, and an experiment was designed to induce emotions and obtain high-density body surface potential information under negative and non-negative emotions. Then, by constructing and analyzing the functional connectivity network of BSPs, the high-density electrophysiological characteristics are obtained and visualized as bodily emotion maps. The results showed that the functional connectivity network of BSPs under negative emotions had denser connections, and emotion maps based on local clustering coefficient (LCC) are consistent with BSMs under negative emotions. in addition, our features can classify negative and non-negative emotions with the highest classification accuracy of 80.77%. In conclusion, this study constructs an emotion map based on high-density BSPs, which offers a novel approach to psychophysiological computing.

3.
Article in English | MEDLINE | ID: mdl-37478039

ABSTRACT

With the development of brain-computer interfaces (BCI) technologies, EEG-based BCI applications have been deployed for medical purposes. Motor imagery (MI), applied to promote neural rehabilitation for stroke patients, is among the most common BCI paradigms that. The Electroencephalogram (EEG) signals, encompassing an extensive range of channels, render the training dataset a high-dimensional construct. This high dimensionality, inherent in such a dataset, tends to challenge traditional deep learning approaches, causing them to potentially disregard the intrinsic correlations amongst these channels. Such an oversight often culminates in erroneous data classification, presenting a significant drawback of these conventional methodologies. In our study, we propose a novel algorithmic structure of EEG channel-attention combined with Swin Transformer for motor pattern recognition in BCI rehabilitation. Effectively, the self-attention module from transformer architecture could captures temporal-spectral-spatial features hidden in EEG data. The experimental results verify that our proposed methods outperformed other state-of-art approaches with the average accuracy of 87.67%. It is implied that our method can extract high-level and latent connections among temporal-spectral features in contrast to traditional deep learning methods. This paper demonstrates that channel-attention combined with Swin Transformer methods has great potential for implementing high-performance motor pattern-based BCI systems.


Subject(s)
Algorithms , Brain-Computer Interfaces , Humans , Imagination , Electroencephalography/methods , Attention
4.
Bioengineering (Basel) ; 10(5)2023 Apr 26.
Article in English | MEDLINE | ID: mdl-37237599

ABSTRACT

Even with over 80% of the population being vaccinated against COVID-19, the disease continues to claim victims. Therefore, it is crucial to have a secure Computer-Aided Diagnostic system that can assist in identifying COVID-19 and determining the necessary level of care. This is especially important in the Intensive Care Unit to monitor disease progression or regression in the fight against this epidemic. To accomplish this, we merged public datasets from the literature to train lung and lesion segmentation models with five different distributions. We then trained eight CNN models for COVID-19 and Common-Acquired Pneumonia classification. If the examination was classified as COVID-19, we quantified the lesions and assessed the severity of the full CT scan. To validate the system, we used Resnetxt101 Unet++ and Mobilenet Unet for lung and lesion segmentation, respectively, achieving accuracy of 98.05%, F1-score of 98.70%, precision of 98.7%, recall of 98.7%, and specificity of 96.05%. This was accomplished in just 19.70 s per full CT scan, with external validation on the SPGC dataset. Finally, when classifying these detected lesions, we used Densenet201 and achieved accuracy of 90.47%, F1-score of 93.85%, precision of 88.42%, recall of 100.0%, and specificity of 65.07%. The results demonstrate that our pipeline can correctly detect and segment lesions due to COVID-19 and Common-Acquired Pneumonia in CT scans. It can differentiate these two classes from normal exams, indicating that our system is efficient and effective in identifying the disease and assessing the severity of the condition.

6.
Sensors (Basel) ; 23(3)2023 Feb 01.
Article in English | MEDLINE | ID: mdl-36772604

ABSTRACT

Ankle injuries caused by the Anterior Talofibular Ligament (ATFL) are the most common type of injury. Thus, finding new ways to analyze these injuries through novel technologies is critical for assisting medical diagnosis and, as a result, reducing the subjectivity of this process. As a result, the purpose of this study is to compare the ability of specialists to diagnose lateral tibial tuberosity advancement (LTTA) injury using computer vision analysis on magnetic resonance imaging (MRI). The experiments were carried out on a database obtained from the Vue PACS-Carestream software, which contained 132 images of ATFL and normal (healthy) ankles. Because there were only a few images, image augmentation techniques was used to increase the number of images in the database. Following that, various feature extraction algorithms (GLCM, LBP, and HU invariant moments) and classifiers such as Multi-Layer Perceptron (MLP), Support Vector Machine (SVM), k-Nearest Neighbors (kNN), and Random Forest (RF) were used. Based on the results from this analysis, for cases that lack clear morphologies, the method delivers a hit rate of 85.03% with an increase of 22% over the human expert-based analysis.


Subject(s)
Ankle Injuries , Lateral Ligament, Ankle , Humans , Ankle/diagnostic imaging , Ankle Joint , Lateral Ligament, Ankle/diagnostic imaging , Lateral Ligament, Ankle/injuries , Magnetic Resonance Imaging/methods , Ankle Injuries/diagnostic imaging , Computers
7.
Bioengineering (Basel) ; 10(1)2023 Jan 13.
Article in English | MEDLINE | ID: mdl-36671687

ABSTRACT

Measurement uncertainty is one of the widespread concepts applied in scientific works, particularly to estimate the accuracy of measurement results and to evaluate the conformity of products and processes. In this work, we propose a methodology to analyze the performance of measurement systems existing in the design phases, based on a probabilistic approach, by applying the Monte Carlo method (MCM). With this approach, it is feasible to identify the dominant contributing factors of imprecision in the evaluated system. In the design phase, this information can be used to identify where the most effective attention is required to improve the performance of equipment. This methodology was applied over a simulated electrocardiogram (ECG), for which a measurement uncertainty of the order of 3.54% of the measured value was estimated, with a confidence level of 95%. For this simulation, the ECG computational model was categorized into two modules: the preamplifier and the final stage. The outcomes of the analysis show that the preamplifier module had a greater influence on the measurement results over the final stage module, which indicates that interventions in the first module would promote more significant performance improvements in the system. Finally, it was identified that the main source of ECG measurement uncertainty is related to the measurand, focused towards the objective of better characterization of the metrological behavior of the measurements in the ECG.

8.
Sensors (Basel) ; 22(22)2022 Nov 15.
Article in English | MEDLINE | ID: mdl-36433415

ABSTRACT

Breast cancer is the type of cancer with the highest incidence and global mortality of female cancers. Thus, the adaptation of modern technologies that assist in medical diagnosis in order to accelerate, automate and reduce the subjectivity of this process are of paramount importance for an efficient treatment. Therefore, this work aims to propose a robust platform to compare and evaluate the proposed strategies for improving breast ultrasound images and compare them with state-of-the-art techniques by classifying them as benign, malignant and normal. Investigations were performed on a dataset containing a total of 780 images of tumor-affected persons, divided into benign, malignant and normal. A data augmentation technique was used to scale up the corpus of images available in the chosen dataset. For this, novel image enhancement techniques were used and the Multilayer Perceptrons, k-Nearest Neighbor and Support Vector Machines algorithms were used for classification. From the promising outcomes of the conducted experiments, it was observed that the bilateral algorithm together with the SVM classifier achieved the best result for the classification of breast cancer, with an overall accuracy of 96.69% and an accuracy for the detection of malignant nodules of 95.11%. Therefore, it was found that the application of image enhancement methods can help in the detection of breast cancer at a much earlier stage with better accuracy in detection.


Subject(s)
Mammography , Paraganglioma , Female , Humans , Image Enhancement , Ultrasonography, Mammary , Algorithms , Records
9.
Biomedicines ; 10(11)2022 Oct 28.
Article in English | MEDLINE | ID: mdl-36359266

ABSTRACT

Parkinson's disease (PD) is the most common form of Parkinsonism, which is a group of neurological disorders with PD-like motor impairments. The disease affects over 6 million people worldwide and is characterized by motor and non-motor symptoms. The affected person has trouble in controlling movements, which may affect simple daily-life tasks, such as typing on a computer. We propose the application of a modified SqueezeNet convolutional neural network (CNN) for detecting PD based on the subject's key-typing patterns. First, the data are pre-processed using data standardization and the Synthetic Minority Oversampling Technique (SMOTE), and then a Continuous Wavelet Transformation is applied to generate spectrograms used for training and testing a modified SqueezeNet model. The modified SqueezeNet model achieved an accuracy of 90%, representing a noticeable improvement in comparison to other approaches.

10.
Article in English | MEDLINE | ID: mdl-35969547

ABSTRACT

Motor-modality-based brain computer interface (BCI) could promote the neural rehabilitation for stroke patients. Temporal-spatial analysis was commonly used for pattern recognition in this task. This paper introduced a novel connectivity network analysis for EEG-based feature selection. The network features of connectivity pattern not only captured the spatial activities responding to motor task, but also mined the interactive pattern among these cerebral regions. Furthermore, the effective combination between temporal-spatial analysis and network analysis was evaluated for improving the performance of BCI classification (81.7%). And the results demonstrated that it could raise the classification accuracies for most of patients (6 of 7 patients). This proposed method was meaningful for developing the effective BCI training program for stroke rehabilitation.


Subject(s)
Brain-Computer Interfaces , Stroke Rehabilitation , Stroke , Electroencephalography/methods , Humans , Imagination , Spatial Analysis
11.
Comput Intell Neurosci ; 2022: 2728866, 2022.
Article in English | MEDLINE | ID: mdl-36039344

ABSTRACT

Coronavirus disease (COVID-19) has created an unprecedented devastation and the loss of millions of lives globally. Contagious nature and fatalities invariably pose challenges to physicians and healthcare support systems. Clinical diagnostic evaluation using reverse transcription-polymerase chain reaction and other approaches are currently in use. The Chest X-ray (CXR) and CT images were effectively utilized in screening purposes that could provide relevant data on localized regions affected by the infection. A step towards automated screening and diagnosis using CXR and CT could be of considerable importance in these turbulent times. The main objective is to probe a simple threshold-based segmentation approach to identify possible infection regions in CXR images and investigate intensity-based, wavelet transform (WT)-based, and Laws based texture features with statistical measures. Further feature selection strategy using Random Forest (RF) then selected features used to create Machine Learning (ML) representation with Support Vector Machine (SVM) and a Random Forest (RF) to make different COVID-19 from viral pneumonia (VP). The results obtained clearly indicate that the intensity and WT-based features vary in the two pathologies that are better differentiated with the combined features trained using SVM and RF classifiers. Classifier performance measures like an Area Under the Curve (AUC) of 0.97 and by and large classification accuracy of 0.9 using the RF model clearly indicate that the methodology implemented is useful in characterizing COVID-19 and Viral Pneumonia.


Subject(s)
COVID-19 , Pneumonia, Viral , COVID-19/diagnosis , Humans , Machine Learning , Pneumonia, Viral/diagnosis , Support Vector Machine , Tomography, X-Ray Computed/methods
12.
Appl Soft Comput ; 123: 108966, 2022 Jul.
Article in English | MEDLINE | ID: mdl-35582662

ABSTRACT

The COVID-19 pandemic continues to wreak havoc on the world's population's health and well-being. Successful screening of infected patients is a critical step in the fight against it, with radiology examination using chest radiography being one of the most important screening methods. For the definitive diagnosis of COVID-19 disease, reverse-transcriptase polymerase chain reaction remains the gold standard. Currently available lab tests may not be able to detect all infected individuals; new screening methods are required. We propose a Multi-Input Transfer Learning COVID-Net fuzzy convolutional neural network to detect COVID-19 instances from torso X-ray, motivated by the latter and the open-source efforts in this research area. Furthermore, we use an explainability method to investigate several Convolutional Networks COVID-Net forecasts in an effort to not only gain deeper insights into critical factors associated with COVID-19 instances, but also to aid clinicians in improving screening. We show that using transfer learning and pre-trained models, we can detect it with a high degree of accuracy. Using X-ray images, we chose four neural networks to predict its probability. Finally, in order to achieve better results, we considered various methods to verify the techniques proposed here. As a result, we were able to create a model with an AUC of 1.0 and accuracy, precision, and recall of 0.97. The model was quantized for use in Internet of Things devices and maintained a 0.95 percent accuracy.

13.
IEEE J Biomed Health Inform ; 26(12): 5772-5782, 2022 12.
Article in English | MEDLINE | ID: mdl-35511842

ABSTRACT

Atrial fibrillation (AF) is a serious medical condition of the heart potentially leading to stroke, which can be diagnosed by analyzing electrocardiograms (ECG). Technologies of Artificial Intelligence of Things (AIoT) enable smart abnormality detection by analyzing streaming healthcare data from the sensor end of users. Analyzing streaming data in the cloud leads to challenges of response latency and privacy issues, and local inference by a model deployed on the user end brings difficulties in model update and customization. Therefore, we propose an AIoT Platform with AF recognition neural networks on the sensor edge with model retraining ability on a resource-constrained embedded system. To this aim, we proposed to combine simple but effective neural networks and an ECG feature selection strategy to reduce computing complexity while maintaining recognition performance. Based on the platform, we evaluated and discussed the performance, response time, and requirements for model retraining in the scenario of AF detection from ECG recordings. The proposed lightweight solution was validated with two public datasets and an ECG data stream simulation on an ATmega2560 processor, proving the feasibility of analysis and training on edge.


Subject(s)
Atrial Fibrillation , Humans , Atrial Fibrillation/diagnosis , Artificial Intelligence , Neural Networks, Computer , Electrocardiography , Computer Simulation
14.
IEEE J Biomed Health Inform ; 26(8): 3607-3617, 2022 08.
Article in English | MEDLINE | ID: mdl-34847047

ABSTRACT

Affective brain computer interface (ABCI) enables machines to perceive, understand, express and respond to people's emotions. Therefore, it is expected to play an important role in emotional care and mental disorder detection. EEG signals are most frequently adopted as the physiology measurement in ABCI applications. Eye blinking and movements introduce lots of artifacts into raw EEG data, which seriously affect the quality of EEG signal and the subsequent emotional EEG feature engineering and recognition. In this paper, we propose a fully automatic and unsupervised ocular artifact identification and removal algorithm named automated canonical correlation analysis (CCA)-multi-channel wiener filter (MWF) (ACCAMWF). Firstly, spatial distribution entropy (SDE) and spectral entropy (SE) are computed to automatically annotate artifact segments. Then, CCA algorithm is used to extract neural signal from artifact contaminated data to further supplement the clean EEG data. Finally, MWF is trained to remove ocular artifacts from multiple channel EEG data adaptively. Extensive experiments have been carried out on semi-simulated EEG/EOG dataset and real eye blinking-contaminated EEG dataset to verify the effectiveness of our method when compared to two state-of-the-art algorithms. The results clearly demonstrate that ACCAMWF is a promising solution for removing EOG artifacts from emotional EEG data.


Subject(s)
Artifacts , Brain-Computer Interfaces , Algorithms , Electroencephalography/methods , Electrooculography/methods , Humans , Signal Processing, Computer-Assisted
15.
IEEE Trans Image Process ; 30: 8968-8982, 2021.
Article in English | MEDLINE | ID: mdl-34613913

ABSTRACT

Due to the rapid development of artificial intelligence technology, industrial sectors are revolutionizing in automation, reliability, and robustness, thereby significantly increasing quality and productivity. Most of the surveillance and industrial sectors are monitored by visual sensor networks capturing different surrounding environment images. However, during tempestuous weather conditions, the visual quality of the images is reduced due to contaminated suspended atmospheric particles that affect the overall surveillance systems. To tackle these challenges, this article presents a computationally efficient lightweight convolutional neural network referred to as Light-DehazeNet (LD-Net) for the reconstruction of hazy images. Unlike other learning-based approaches, which separately measure the transmission map and the atmospheric light, our proposed LD-Net jointly estimates both the transmission map and the atmospheric light using a transformed atmospheric scattering model. Furthermore, a color visibility restoration method is proposed to evade the color distortion in the dehaze image. Finally, we conduct extensive experiments using synthetic and natural hazy images. The quantitative and qualitative evaluation on different benchmark hazy datasets verify the superiority of the proposed method over other state-of-the-art image dehazing techniques. Moreover, additional experimentation validates the applicability of the proposed method in the object detection tasks. Considering the lightweight architecture with minimal computational cost, the proposed system is encouraged to be incorporated as an integral part of the vision-based monitoring systems to improve the overall performance.

17.
IEEE J Biomed Health Inform ; 25(12): 4267-4275, 2021 12.
Article in English | MEDLINE | ID: mdl-33750716

ABSTRACT

Teledermatology is one of the most illustrious applications of telemedicine and e-health. In this field, telecommunication technologies are utilized to transfer medical information to the experts. Due to the skin's visual nature, teledermatology is an effective tool for the diagnosis of skin lesions especially in rural areas. Furthermore, it can also be useful to limit gratuitous clinical referrals and triage dermatology cases. The objective of this research is to classify the skin lesion image samples, received from different servers. The proposed framework is comprised of two module, which include the skin lesion localization/segmentation and the classification. In the localization module, we propose a hybrid strategy that fuses the binary images generated from the designed 16-layered convolutional neural network model and an improved high dimension contrast transform (HDCT) based saliency segmentation. To utilize maximum information extracted from the binary images, a maximal mutual information method is proposed, which returns the segmented RGB lesion image. In the classification module, a pre-trained DenseNet201 model is re-trained on the segmented lesion images using transfer learning. Afterward, the extracted features from the two fully connected layers are down-sampled using the t-distribution stochastic neighbor embedding (t-SNE) method. These resultant features are finally fused using a multi canonical correlation (MCCA) approach and are passed to a multi-class ELM classifier. Four datasets (i.e., ISBI2016, ISIC2017, PH2, and ISBI2018) are employed for the evaluation of the segmentation task, while HAM10000, the most challenging dataset, is used for the classification task. The experimental results in comparison with the state-of-the-art methods affirm the strength of our proposed framework.


Subject(s)
Skin Diseases , Skin Neoplasms , Canonical Correlation Analysis , Dermoscopy , Humans , Image Processing, Computer-Assisted , Neural Networks, Computer , Skin Diseases/diagnostic imaging
18.
J Real Time Image Process ; 18(4): 1099-1114, 2021.
Article in English | MEDLINE | ID: mdl-33747237

ABSTRACT

Pneumonia is responsible for high infant morbidity and mortality. This disease affects the small air sacs (alveoli) in the lung and requires prompt diagnosis and appropriate treatment. Chest X-rays are one of the most common tests used to detect pneumonia. In this work, we propose a real-time Internet of Things (IoT) system to detect pneumonia in chest X-ray images. The dataset used has 6000 chest X-ray images of children, and three medical specialists performed the validations. In this work, twelve different architectures of Convolutional Neural Networks (CNNs) trained on ImageNet were adapted to operate as the resource extractors. Subsequently, the CNNs were combined with consolidated learning methods, such as k-Nearest Neighbor (kNN), Naive Bayes, Random Forest, Multilayer Perceptron (MLP), and Support Vector Machine (SVM). The results showed that the VGG19 architecture with the SVM classifier using the RBF kernel was the best model to detect pneumonia in these chest radiographs. This combination reached 96.47%, 96.46%, and 96.46% for Accuracy, F1 score, and Precision values, respectively. Compared to other works in the literature, the proposed approach had better results for the metrics used. These results show that this approach for the detection of pneumonia in children using a real-time IoT system is efficient and is, therefore, a potential tool to aid in medical diagnoses. This approach will allow specialists to obtain faster and more accurate results and thus provide the appropriate treatment.

19.
Comput Biol Med ; 131: 104260, 2021 04.
Article in English | MEDLINE | ID: mdl-33596483

ABSTRACT

Parkinson's disease (PD) is a progressive neurodegenerative illness associated with motor skill disorders, affecting thousands of people, mainly elderly, worldwide. Since its symptoms are not clear and commonly confused with other diseases, providing early diagnosis is a challenging task for traditional methods. In this context, computer-aided assistance is an alternative method for a fast and automatic diagnosis, accelerating the treatment and alleviating an excessive effort from professionals. Moreover, the most recent studies proposing a solution to this problem lack in computational efficiency, prediction power, reliability among other factors. Therefore, this work proposes a Fuzzy Optimum Path Forest for automated PD identification, which is based on fuzzy logic and graph-based framework theory. Experiments consider a dataset composed of features extracted from hand-drawn images using Restricted Boltzmann Machines, and results are compared with baseline models such as Support Vector Machines, KNN, and the standard OPF classifier. Results show that the proposed model outperforms the baselines in most cases, suggesting the Fuzzy OPF as a viable alternative to deal with PD detection problems.


Subject(s)
Parkinson Disease , Aged , Algorithms , Diagnosis, Computer-Assisted , Forests , Fuzzy Logic , Humans , Parkinson Disease/diagnosis , Reproducibility of Results , Support Vector Machine
20.
IEEE Internet Things J ; 8(21): 15652-15662, 2021 Nov 01.
Article in English | MEDLINE | ID: mdl-35582243

ABSTRACT

Internet of Medical Things (IoMT)-driven smart health and emotional care is revolutionizing the healthcare industry by embracing several technologies related to multimodal physiological data collection, communication, intelligent automation, and efficient manufacturing. The authentication and secure exchange of electronic health records (EHRs), comprising of patient data collected using wearable sensors and laboratory investigations, is of paramount importance. In this article, we present a novel high payload and reversible EHR embedding framework to secure the patient information successfully and authenticate the received content. The proposed approach is based on novel left data mapping (LDM), pixel repetition method (PRM), RC4 encryption, and checksum computation. The input image of size [Formula: see text] is upscaled by using PRM that guarantees reversibility with lesser computational complexity. The binary secret data are encrypted using the RC4 encryption algorithm and then the encrypted data are grouped into 3-bit chunks and converted into decimal equivalents. Before embedding, these decimal digits are encoded by LDM. To embed the shifted data, the cover image is divided into [Formula: see text] blocks and then in each block, two digits are embedded into the counter diagonal pixels. For tamper detection and localization, a checksum digit computed from the block is embedded into one of the main diagonal pixels. A fragile logo is embedded into the cover images in addition to EHR to facilitate early tamper detection. The average peak signal to noise ratio (PSNR) of the stego-images obtained is 41.95 dB for a very high embedding capacity of 2.25 bits per pixel. Furthermore, the embedding time is less than 0.2 s. Experimental results reveal that our approach outperforms many state-of-the-art techniques in terms of payload, imperceptibility, computational complexity, and capability to detect and localize tamper. All the attributes affirm that the proposed scheme is a potential candidate for providing better security and authentication solutions for IoMT-based smart health.

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