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Med Cutan Ibero Lat Am ; 17(2): 103-4, 1989.
Article in Portuguese | MEDLINE | ID: mdl-2666794

ABSTRACT

Report on a case of dapsone resistance in a BL patient with clinical diagnosis and laboratory confirmation. The resistance appeared after 17 years of dapsone treatment, and the laboratory tests revealed total resistance to all the tested dapsone concentrations. The case reported occurred in the city of Rio de Janeiro (Brazil) which presents a leprosy prevalence of 1.79/1,000.


Subject(s)
Dapsone/pharmacology , Leprosy, Borderline/drug therapy , Mycobacterium leprae/drug effects , Aged , Aged, 80 and over , Animals , Brazil , Dapsone/therapeutic use , Drug Resistance, Microbial , Humans , Male , Mice , Mice, Inbred BALB C
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