Colocación de catéter de hemodiálisis transceldas de stent en paciente con agotamiento de acceso venoso / Trans-cells of stent hemodialysis catheter placement in patients with exhausted central venous Access

INTRODUCCIÓN: el agotamiento vascular es un problema sanitario significativo, sobre todo en pacientes renales que no sean aptos para otro tipo de terapia de sustitución renal (trasplante o diálisis peritoneal). Se describen distintas alternativas para estos pacientes, de acuerdo a las posibilidades. CASO CLÍNICO: exponemos el caso de una mujer de 37 años, con enfermedad renal terminal desde hace más de treinta años por esclerohialinosis focal y segmentaria de variante colapsante y agotamiento del capital venoso central. Acude a nuestro centro con infección de Splithcath III(R) (MedComp), que se retira para colocar dos catéteres venosos simples de 6 Fr a nivel del tronco innominado vía yugular interna izquierda, al fallar en una navegación más central. Se destaca que la paciente presenta una vena yugular, vena subclavia y tronco innominado derechos ocluidos, con oclusión larga en el sitio donde se colocó un stent Palmaz(R) (Genesis Medical Group) en contexto de confección de fístula protésica, que cruza completamente la vena cava superior impidiendo el paso desde las venas izquierdas. Se optó por la implantación de un catéter de larga duración a través de las celdas del stent, llevada a cabo con éxito, con síndrome de vena cava superior de resolución posterior como complicación. DISCUSIÓN: lo más significativo de esta presentación es el implante a través de las celdas de un stent de catéteres de diálisis. Hasta ahora, encontramos descrita solo la colocación endoluminal y no esta técnica. Creemos que se trata de una alternativa válida en casos puntuales, como el analizado

INTRODUCTION: exhausted vascular access in chronic renal disease patients represents a significant issue for national health systems all around. It is fundamentally worse for those patients who have already surpassed or have no indication for other methods (renal transplant, peritoneal dilalysis). Different alternatives are assessed for each of these patients according to individual history. CASE REPORT: we assess the case of a 37 year old female patient with end-stage renal disease secondary to focal esclerohialinosis. Said patient has exhausted vascular access, as a consult for infected Splithcath III(R) (MedComp) for retrieval. Two simple 6Fr standard venous catheters were placed instead through the left jugular vein, with their tips in the left innominate vein lumen for a fail in mor central navigation. Patient concomitantly presented right jugular, subclavian and innominate veins obstructed, treated with a Palmaz(R) (Genesis Medical Group) metallic stent prior to right arteriovenous graft confection. That stent was across the lumen of the superior vena Cava. We opted for the implantation of a long-lasting dialysis catheter through the cells of the mentioned stent, which was successful despite complicaciones (superior vena cava syndrome). DISCUSSION: the most relevant topic of this case is the trans-stent cell implant of dialysis catheters. Research finds evidence only of transluminal stent central vein catheters implanted. We believe it constitutes a valid alternative in special cases such as the one being exposed

Milk adulteration with acidified rennet whey: a limitation for caseinomacropeptide detection by high-performance liquid chromatography.

BACKGROUND: High-performance liquid chromatography (HPLC) is widely employed to determine the caseinomacropeptide (CMP) index and to detect milk tampering with rennet whey. Prior to HPLC analysis, CMP is subject to a trichloracetic acid isolation, causing further soluble proteins in the sample to precipitate. On this basis, we aimed to determine whether rennet whey acidification could adversely affect the HPLC sensitivity with respect to detecting this peptide. RESULTS: As hypothesized, the CMP index from milk with added acidified rennet whey was, on average, half that quantified from milk with added rennet whey. Moreover, the quantum satis of acidified whey added to milk sufficient to demonstrate a HPLC CMP > 30 mg L-1 was 94% greater than that required for this threshold to be reached with rennet whey. CONCLUSION: Milk tampering with acidified rennet whey may limit the analytical sensitivity of the reversed-phase HPLC employed for the screening of CMP and, ultimately, disguise the fraudulent addition of whey to milk. © 2017 Society of Chemical Industry.