Evolution of physical function, cognition, depressive mood, and quality of life during the Covid-19 pandemic in prefrail elderly people: A longitudinal cohort study (Covid-Mefap).

Confinement due to the COVID-19 pandemic has had a major impact on the living habits and health of the population, notably in the pre-frail elderly. This study aimed to study the effect of the COVID-19 pandemic on the physical function, mental function (cognition and mood), and quality of life of pre-frail elderly individuals over 70 years of age following confinement as well as to analyze the variables associated with the observed changes. METHODS: Observational study of a cohort of pre-frail community-dwelling older adults over 70 years of age during the COVID-19 pandemic conducted in primary care. VARIABLES: The main outcome variables were recorded during face-to-face interviews between December 14 of 2020 and August 12 of 2021 using scales for the evaluation of physical function (Short Physical Performance Battery), cognition (Lobo's Mini-Examen Cognoscitivo), depressive mood (Geriatric Depression Scale), and quality of life (EuroQol-5D-3L). Covariates: sociodemographic data and variables related to the pandemic and general health (social support network, COVID-19 infection, exercising, and leisure activities) were also collected. ANALYSIS: The Student's t-test for paired samples and multivariate linear regression models were employed for the statistical analyses. RESULTS: Ninety-two subjects were included in the study. Physical function, cognition, and depressive mood improved during the pandemic, whereas no changes were observed in quality of life. Suffering from COVID-19 was associated with deterioration of the cognitive function (-1.460; CI95%: -2.710 to -0.211). CONCLUSION: Confinement due to the COVID-19 pandemic was not associated with a decline in physical function, cognition, depressive mood, or quality of life in pre-frail individuals over 70 years of age.

Impact of Psoriasis and Hidradenitis Suppurativa in Pregnancy, a Systematic Review.

Psoriasis and hidradenitis suppurativa (HS) are chronic inflammatory skin diseases that frequently develop in young women. The aim of this study is to evaluate how hidradenitis suppurativa and psoriasis impact women desiring to conceive, and their influence on fertility and gestation. A systematic review of articles dating from January 2015 to April 2021 was performed using the Scopus (Elsevier) database. The search terms were (psoriasis and (birth or pregnancy or fertility)) and ((hidradenitis suppurativa or acne inversa) and (birth or pregnancy or fertility)). The search was limited to human data. Systematic reviews, case reports, clinical practice guidelines, expert consensus and conference papers were excluded. The impact of HS on pregnancy includes an impaired desire for pregnancy, a decrease in fertility, the worsening of the disease during pregnancy and potential adverse events during pregnancy. Moreover, the pregnancy might imply a change on the treatment of HS. The impact of psoriasis on pregnancy includes a decrease in fertility, potential adverse events during pregnancy and an unpredictable evolution of the disease. Moreover, the pregnancy might imply a change on the treatment of psoriasis, although biologic therapies do not appear to increase the risk of adverse events. In conclusion, both HS and psoriasis have an impact on pregnancy. A decrease of fertility has been reported. Moreover, both diseases have an unpredictable evolution during pregnancy. Pregnant women who are under biologic therapy do not seem to have a higher rate of adverse events. Treatment of both conditions is usually halted during pregnancy since scientific evidence about their safety is not conclusive, or teratogenic risk has been proven.

Aportes científicos del Instituto de Medicina Tropical "Pedro Kouri" a la vigilancia de Aedes aegypti (Díptera: Culicidae) en Cuba, 1982-2020

RESUMEN Entre las enfermedades de mayor incidencia en el mundo transmitidas por los culícidos o mosquitos se encuentran las arbovirosis como dengue, chikungunya, zika y fiebre amarilla, las cuales el humano las adquiere a través de la picadura de Aedes aegypti (Linnaeus, 1762) y Aedes albopictus (Skuse, 1894). Los programas de vigilancia entomológica de Ae. aegypti en el mundo tienen en común determinar cambios en la distribución geográfica del mosquito, obtener medidas relativas de sus poblaciones a lo largo del tiempo, evaluar la cobertura y el impacto de las intervenciones antivectoriales, así como monitorear la susceptibilidad y la resistencia de sus poblaciones a los principales insecticidas usados en el control vectorial. En este trabajo se resume los principales resultados de las investigaciones desarrolladas por el departamento de control de vectores del Instituto de Medicina Tropical ¨Pedro Kouri¨ (IPK) como Laboratorio Nacional de Referencia (LNR) para contribuir al fortalecimiento de la vigilancia entomológica de Ae. aegypti desde 1981 hasta el 2020. Con este artículo se destaca el trabajo realizado al cumplirse en el 2021, 40 años del inicio de la llamada campaña de erradicación de Ae. aegypti implementada a raíz de la epidemia de dengue hemorrágico (en la nueva clasificación denominada dengue severo) registrada en Cuba en 1981.

ABSTRACT Arbovirus infections such as dengue, chikungunya, zika and yellow fever are among the mosquito-borne diseases with the highest incidence worldwide. These conditions are transmitted by the bite of Aedes aegypti (Linnaeus, 1762) and Aedes albopictus (Skuse, 1894) mosquitoes. Common goals of entomological surveillance programs for Ae. aegypti in the world are to determine changes in the geographic distribution of the mosquito, obtain data concerning their populations throughout time, evaluate the coverage and impact of antivector interventions, and monitor the susceptibility and resistance of mosquito populations to the main insecticides used for vector control. The paper summarizes the main results of studies conducted from 1981 to 2020 by the Vector Control Department at Pedro Kourí Tropical Medicine Institute (IPK) as a National Reference Laboratory (NRL), to contribute to the strengthening of entomological surveillance of Ae. aegypti. Recognition is also made of the work done for forty years as part of the so-called Ae. aegypti eradication campaign implemented in response to the dengue hemorrhagic fever epidemic (severe dengue in the new classification) occurring in Cuba in 1981.

[Quality of life and physical activity in prefrail individuals over 70 years in primary care.] / Calidad de vida y actividad física en individuos prefrágiles mayores de 70 años en atención primaria.

OBJECTIVE: Frailty is an increasing problem among the elderly people and it is more frequent in women. Physical activity improves either the function and quality of life. Given the diferences reported by the literature about the quality of life perception and the physical activity practice between men and women, the aim of this study is to analyze the association between health related quality of life (HRQoL) and physical activity in a pre-frail population and to study its relationship with gender. METHODS: Descriptive study in pre-frail individuals over 70 years old assigned to twelve primary care health centers carried out between 2018 Jun and 2020 March in Madrid. The studied variables were registered by clinical interview: Physical activity (Yale), HRQoL (EQ-5D-3L), sociodemographic and clinical variables (comorbidity, depression and pain). Descriptive analysis and multiple linear regression for the whole population and stratified by gender, using the quality of life as dependent variable. RESULTS: The study involved 206 pre-frail individuals (152 women) wih an average age of 78 years. Women had less comorbidity (32.3% versus 55.6%) but more pain (60.5% versus 44.4%) than men. The median of physical activity was 40 points (55.9% of that score was attributable to relaxed walk). HRQoL was 0.74 in utility score and 68 in the EQ-VAS. No differences were found by gender. To walk more than 5 hours a week was found associated with better quality of life by EQ-5D utility score (0.08, IC95%: 0.03 to 0.14), and by EQ-VAS score (5.38, IC95%: 0.25 to 10.51). CONCLUSIONS: Physical activity was associated to better quality of life in a pre-frail population of individuals older than 70 years old.

OBJETIVO: La fragilidad es un problema de creciente magnitud entre los mayores que afecta en mayor proporción a mujeres. La actividad física mejora tanto la funcionalidad como la calidad de vida. Dadas las diferencias en la percepción de la calidad de vida y en la práctica de actividad física entre hombres y mujeres, se planteó como objetivo analizar la asociación entre calidad de vida y actividad física en mayores de 70 años prefrágiles y su relación con el sexo. METODOS: Estudio descriptivo en mayores de 70 años prefrágiles realizado entre junio de 2018 y marzo de 2020 en 12 centros de salud de Madrid. Se recogieron mediante entrevista clínica, variables de actividad física (cuestionario de Yale), calidad de vida (Euroqol-5D); variables sociodemográficas y de salud (comorbilidad, depresión y dolor). Se realizó análisis descriptivo y modelos de regresión lineal múltiple con calidad de vida como variable dependiente (total población y por sexo). RESULTADOS: Participaron en el estudio 206 individuos (152 mujeres), con una edad media de 78 años. Las mujeres presentaron menos comorbilidad (32,3% versus 55,6%) y más dolor (60,5% versus 44,4%) que los hombres. La media de actividad física fue de 40 puntos (55,9% de la puntuación corresponde a pasear relajadamente). La calidad de vida fue de 0,74 segun utilidades y de 68 en la EVA-EQ5D, sin diferencias según sexo. Pasear más de 5 horas/semana se asoció a mejor calidad de vida según utilidades (0,08, IC95%: 0,03 a 0,14), y según EVA (5,38, IC95%: 0,25 a 10,51). CONCLUSIONES: La actividad física se asoció a una mejor calidad de vida en población prefrágil mayor de 70 años.

Efficacy of prompted voiding for reversing urinary incontinence in older adults hospitalized in a functional recovery unit: Study protocol.

AIMS: To assess the efficacy of a prompted voiding programme for restoring urinary continence at discharge in hospitalized older adults who presented with reversible urinary incontinence (UI) on admission to a functional recovery unit (FRU). To assess the maintenance of the outcomes achieved after hospitalization. To identify modifiable and unmodifiable factors associated with the success of the prompted voiding programme. DESIGN: Quasi-experimental, pre-/post-intervention study without a control group. METHODS: Participants were aged 65 and over with a history of reversible UI in the previous year who had been admitted to a FRU and were on a prompted voiding programme throughout their hospitalization period. The sample consisted of 221 participants. A non-probabilistic sampling method, in order of recruitment after signing the informed consent form, was used. The primary outcomes were UI assessed at discharge and 1 month, 3 months and 6 months after discharge. Funding was granted in July 2019 by the Spain Health Research Fund (PI19/00168, Ministry of Health). The proposal was approved by the Spanish Research Ethics Committee. DISCUSSION: The prompted voiding programme described can reverse UI or decrease the frequency and amount of urine loss in hospitalized older adults. IMPACT: Urinary incontinence is highly prevalent in hospitalized older adults. There is a need for care aimed at prevention, recovery and symptom control. Prompted voiding is a therapy provided by the nursing team during hospitalization and can also be provided by family caregivers at home after receiving proper training by the nursing team. Prompted voiding will enhance the health, functional ability and quality of life of older adults with UI, resulting in the reduction of associated healthcare costs and the risk of developing complications.

Anti-angiogenic therapy for ovarian cancer.

Angiogenesis is a known hallmark in cancer and plays a crucial role in ovarian cancer carcinogenesis and invasion. Anti- angiogenic agents are active in ovarian cancer treatment either as monotherapy or combined with chemotherapy, immunotherapy or poly ADP ribose polymerase (PARP) inhibitors. We review the mechanism of action, clinical activity and safety profile of the most important drugs either in the actual treatment or in current evaluation in the ovarian cancer treatment scenario (neoadjuvant, first line and relapse).

Riqueza de mosquitos en La Habana: su importancia para fomentar la participación comunitaria en su control / Species mosquito richness in Havana: its importance to promote community participation in its control

Introducción: La identificación de las especies de mosquitos a nivel de cada municipio forma parte del Programa de Vigilancia y Control de Aedes aegypti y Aedes albopictus vigente en Cuba. Objetivo: Identificar las especies de mosquitos en sitios de crías artificiales y naturales y relacionarlo con el papel de la comunidad en el control de sus poblaciones en la provincia La Habana. Métodos: Se identificaron las muestras larvarias de mosquitos enviadas al laboratorio provincial de Entomología, colectadas en depósitos artificiales y en sitios naturales en los municipios de La Habana desde enero del 2000 hasta el 2016. Resultados: En el estudio se identificaron un total de 48 especies de mosquitos. Aedes aegypti, Gymnometopa mediovittata, Culex quinquefasciatus y Culex nigripalpus, estuvieron presentes en todos los municipios de La Habana. Los depósitos abandonados en los alrededores de las viviendas y terrenos baldíos como: latas, bebederos, chatarra metálica, neumáticos de autos usados, entre otros, relacionados con actividades humanas, aportaron la mayor riqueza de especies al ecosistema urbano, seguido por los huecos de árboles y sitios de cría naturales. Los depósitos artificiales de almacenamiento de agua con fines domésticos en las viviendas, tales como: tanques, cisternas, cubos, entre otros, fueron los de menor riqueza, pero fundamentales para la presencia de Ae. aegypti. Conclusiones: Disponer de datos actualizados sobre la distribución de las especies de mosquitos y sus sitios de cría en La Habana constituyen una información valiosa para fomentar la participación de la comunidad en la eliminación de estos en momentos de epidemias en que se involucren estos vectores(AU)

Introduction: Identification of the mosquito species present in each municipality is part of the Aedes aegypti and Aedes albopictus Surveillance and Control Program currently in place in Cuba. Objective: Identify the mosquito species in artificial and natural breeding sites and relate that information to the role played by the community in the control of their populations in the province of Havana. Methods: Identification was performed of mosquito larval samples submitted to the Provincial Entomology Laboratory and collected from artificial containers and natural breeding sites in Havana municipalities from January 2000 to 2016. Results: A total 48 mosquito species were identified in the study. Aedes aegypti, Gymnometopa mediovittata, Culex quinquefasciatus and Culex nigripalpus were found to be present in all Havana municipalities. Unused containers scattered around households and in uncultivated fields, such as cans, troughs, scrap metal and used car tires, among other items related to human activities, contribute the greatest species richness to the urban ecosystem, followed by tree holes and natural breeding sites. Artificial water storage containers in households, such as elevated and underground water tanks and buckets, among others, contributed lesser richness, but were fundamental for the presence of A. aegypti. Conclusions: Updated data about the distribution of mosquito species and their breeding sites in Havana is valuable information to foster community participation in their elimination in the event of epidemics involving these vectors(AU)

The Role of Acculturation and Social Capital in Access to Health Care: A Meta-study on Hispanics in the US.

A meta-study of 83 articles published from 1981 to 2016 was conducted on Hispanics access to health care in the US. Few of these studies have included acculturation and even fewer the role of social capital as important factors that impact healthcare access for this population. Among those that do include these two factors, there is confusion as to how they are defined and operationalized. Acculturation and social capital could serve to overcome some of the structural barriers in place that manifest stronger among Hispanics who are relatively newcomers to a healthcare system that is highly complex to navigate. The majority of studies included in this systematic review of the literature are in public health journals, which do not focus on sociological aspects as much. This study exposes the need to expand the worldviews used in the literature in order to enrich our understanding of access to health care for Hispanics.

Detección de la población mayor susceptible de prescripción de un programa de ejercicios en Atención Primaria para prevenir la fragilidad / Detection of the largest population susceptible to prescription of a program of exercises in Primary Care to prevent frailty

Objetivo: Identificar a la población mayor de 70 años atendida en Atención Primaria, susceptible de participar en un programa de ejercicio físico para prevenir fragilidad. Analizar la concordancia entre 2 criterios para seleccionar la población beneficiaria del programa. Diseño: Estudio transversal de base poblacional. Emplazamiento: Atención Primaria. Participantes: Mayores de 70 años no frágiles residentes del Barrio Peñagrande (distrito Fuencarral, Madrid) pertenecientes a la cohorte de Peñagrande localizables en 2015 y que aceptaron participar (n = 307). Mediciones principales: La variable principal del estudio es la necesidad de prescripción de ejercicio en Atención Primaria en personas mayores de 70 años; se identificó a través de 2 definiciones diferentes: personas prefrágiles (1 o 2 de los 5 criterios de Fried) y personas independientes con desempeño físico limitado, definida por los criterios del documento de consenso sobre prevención de fragilidad y caídas en la persona mayor (mayor de 70 años independiente y con puntuación total del SPPB < 10). Resultados: El 63,84% de los participantes (n = 196) necesitan prescripción del ejercicio por ser prefrágiles y/o por cumplir los criterios definidos en el documento de consenso. En 82 casos cumplían los 2criterios (prefragilidad y desempeño físico disminuido), 80 eran prefrágiles con desempeño físico normal y 34 eran robustos con desempeño físico limitado. La concordancia entre ambos criterios es débil (índice kappa 0,27). Conclusión: Casi 2 tercios de los mayores presentan algún tipo de limitación funcional. Los criterios del documento de consenso para prevenir la fragilidad detectan a la mitad de los individuos prefrágiles de la comunidad

Aim: Identify the population over 70 year's old treated in primary care who should participate in a physical exercise program to prevent frailty. Analyze the concordance among 2 criteria to select the beneficiary population of the program. Design: Population-based cross-sectional study. Settings: Primary Care. Participants: Elderly over 70 years old, living in the Peñagrande neighborhood (Fuencarral district of Madrid) from the Peñagrande cohort, who accepted to participate in 2015 (n = 332). Main measurements: The main variable of the study is the need for exercise prescription in people over 70 years old at the Primary Care setting. It was identified through 2 different definitions: Prefrail (1-2 of 5 Fried criteria) and Independent individuals with physical performance limited, defined by Consensus on frailty and falls prevention among the elderly (independent and with a total SPPB score <10). Results: The 63,8% of participants (n = 196) need exercise prescription based on criteria defined by Fried and/or the consensus for prevention of frailty and falls in the elderly. In 82 cases the 2 criteria were met, 80 were prefrail with normal physical performance and 34 were robust with a limited physical performance. The concordance among both criteria is weak (kappa index 0, 27). Conclusion: Almost 2 thirds of the elderly have some kind of functional limitation. The criteria of the consensus document to prevent frailty detect half of the pre-frail individuals in the community

Falta de adherencia en ancianos frágiles a un programa estructurado multicomponente de ejercicio físico / The lack of adherence to a structured multicomponent program of physical exercise by the frail elderly

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[Detection of the largest population susceptible to prescription of a program of exercises in Primary Care to prevent frailty]. / Detección de la población mayor susceptible de prescripción de un programa de ejercicios en Atención Primaria para prevenir la fragilidad.

AIM: Identify the population over 70 year's old treated in primary care who should participate in a physical exercise program to prevent frailty. Analyze the concordance among 2criteria to select the beneficiary population of the program. DESIGN: Population-based cross-sectional study. SETTINGS: Primary Care. PARTICIPANTS: Elderly over 70 years old, living in the Peñagrande neighborhood (Fuencarral district of Madrid) from the Peñagrande cohort, who accepted to participate in 2015 (n = 332). MAIN MEASUREMENTS: The main variable of the study is the need for exercise prescription in people over 70 years old at the Primary Care setting. It was identified through 2different definitions: Prefrail (1-2 of 5 Fried criteria) and Independent individuals with physical performance limited, defined by Consensus on frailty and falls prevention among the elderly (independent and with a total SPPB score <10). RESULTS: The 63,8% of participants (n = 196) need exercise prescription based on criteria defined by Fried and/or the consensus for prevention of frailty and falls in the elderly. In 82 cases the 2criteria were met, 80 were prefrail with normal physical performance and 34 were robust with a limited physical performance. The concordance among both criteria is weak (kappa index 0, 27). CONCLUSION: Almost 2thirds of the elderly have some kind of functional limitation. The criteria of the consensus document to prevent frailty detect half of the pre-frail individuals in the community.

Variabilidad en la utilización de servicios sanitarios por las personas mayores relacionada con el cupo médico al que pertenecen / Variability in the use of health services by the elderly related to the medical list to which they belong

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Comprehensive geriatric assessment for identifying older people at risk of hip fracture: cross-sectional study with comparative group.

Background: Hip fracture (HF) is by far the most common serious fragility fracture. Its care is a major challenge to all healthcare systems. Aim: To determine whether there are characteristics of older people identified via comprehensive geriatric assessment (CGA) that help identify those with an increased risk of HF. Methods: The demographic, functional, cognitive and nutritional data of a cohort of patients admitted for acute HF were compared with those of a population cohort representing community-dwelling older people in the same urban district without HF. Bivariate analysis was performed on the variables in both the complete samples and in a subsample of age and sex paired subjects, followed by logistic regression analysis. Results: A total of 509 HF patients and 1315 community-dwelling older people were included. The HF patients were older and more frequently women and had more frequent disability and cognitive impairment, lower handgrip strength, lower body mass index (BMI) and a higher frequency of vitamin D deficiency compared with the community controls (P < 0.001). The variables most strongly associated with the presence of HF in the multivariate analysis, aside from age and female sex, were BMI<22 kg/m2 [odds ratio (OR) = 5.11], disability (OR = 4.32), muscle weakness (OR = 3.01), and vitamin D deficiency (OR = 2.13). Conclusions: There are easily obtained CGA determinants that are strongly associated with fragility HF. The detection of low weight, disability, malnutrition, muscle weakness, and vitamin D deficiency can help identify at-risk older people to implement prevention strategies.

Fluoroacetamide Moieties as NMR Spectroscopy Probes for the Molecular Recognition of GlcNAc-Containing Sugars: Modulation of the CH-π Stacking Interactions by Different Fluorination Patterns.

We herein propose the use of fluoroacetamide and difluoroacetamide moieties as sensitive tags for the detection of sugar-protein interactions by simple 1 H and/or 19 F NMR spectroscopy methods. In this process, we have chosen the binding of N,N'-diacetyl chitobiose, a ubiquitous disaccharide fragment in glycoproteins, by wheat-germ agglutinin (WGA), a model lectin. By using saturation-transfer difference (STD)-NMR spectroscopy, we experimentally demonstrate that, under solution conditions, the molecule that contained the CHF2 CONH- moiety is the stronger aromatic binder, followed by the analogue with the CH2 FCONH- group and the natural molecule (with the CH3 CONH- fragment). In contrast, the molecule with the CF3 CONH- isoster displayed the weakest intermolecular interaction (one order of magnitude weaker). Because sugar-aromatic CH-π interactions are at the origin of these observations, these results further contribute to the characterization and exploration of these forces and offer an opportunity to use them to unravel complex recognition processes.

La didáctica de la simulación Clínica: innovar en el sistema de evaluación de competencias. Estudio de caso en la Universidad Nacional del Nordeste / The didactics of clinical simulation: innovate in the system of assessment of competencies. Case study at the University Northeast National

La investigación detalla el estudio sobre las Prácticas Pedagógicas Innovadoras, acotado al ámbito universitario. Estas prácticas poseen características específicas: actitud investigativa, de revisión y transformación de las propias prácticas. El problema de investigación gira en torno a las concepciones docentes, características y valores de utilidad de las prácticas pedagógicas innovadoras de profesores universitarios de la Universidad Nacional del Nordeste. Esta presentación tiene como objetivo, exponer las prácticas pedagógicas innovadoras vinculadas a prácticas de simulación en la enseñanza clínica que llevaron adelante docentes de la Facultad de Medicina de la Universidad Nacional del Nordeste, buscando identificar la influencia de las mismas en el aprendizaje de los estudiantes. Metodológicamente nos encuadramos el paradigma cualitativo, en el tipo descriptivo- explicativo desde un estudio de casos. En este espacio comunicaremos resultados de los análisis que hemos realizado dentro de la "Práctica Final Obligatoria" de la carrera de Medicina, y específicamente en el "Gabinete de Simulación". Entre los resultados sobresalientes mencionamos que el espacio se ubicaría dentro de un Enfoque Didáctico Problematizador, identificando que los docentes se presentan como mediadores entre los estudiantes y la práctica clínica, proporcionando ayudas necesarias para que el sujeto avance progresivamente en la apropiación de los saberes y el ejercicio de las prácticas profesionales. A modo de conclusión, consideramos que estos docentes, promovieron a la innovación educativa como un "cambio justificado"

A investigação detalha o estudo das Práticas Pedagógicas Inovadoras, no âmbito universitário. Essas práticas possuem caraterísticas específicas: atitude investigativa, de revisão e transformação das próprias práticas. O problema da investigação gira em torno das concepções docentes, caraterísticas e valores de utilidade das práticas pedagógicas inovadoras dos professores universitários da Universidad Nacional del Nordeste. Essa apresentação tem como objetivo, expor as práticas pedagógicas inovadoras vinculadas a práticas de simulação no ensino clínico que levaram adiante docentes da Faculdade de Medicina da Universidade Nacional do Nordeste, buscando identificar a influência das mesmas na aprendizagem dos estudantes. Metodologicamente enquadramo-nos no paradigma qualitativo, do tipo descritivo-explicativo a partir do estudo de casos. Neste espaço vamos comunicar os resultados das análises que temos realizado dentro da "Prática Final Obrigatória" da carreira de Medicina, e especificamente no "Gabinete de Simulação". Entre os resultados sobressalientes mencionamos que o espaço estaria dentro da Abordagem Didática Problematizadora, identificando que os docentes se apresentam como mediadores entre os estudantes e a prática clínica, proporcionando ajudas necessárias para que o sujeito avance progressivamente na apropriação de saberes e o exercício das práticas profissionais. A modo de conclusão, consideramos que esses docentes, promoveram à inovação educativa como uma "mudança justificada" . Palavras chaves:-práticas pedagógicas-inovação educativas-simulação crítica

Use of Primary Care Services, Care Specialized and Drug Use by Population 65 Years and More in the Community of Madrid, Spain. / Utilización de servicios de atención primaria, atención especializada y consumo de medicamentos por la población de 65 años y más en la Comunidad de Madrid.

BACKGROUND: Ageing of the Spanish population results in an increase in health services required. Therefore, determine the frequency of the health services utilization in this age group and analyze their determinants has a great interest.The aim was to analyze the utilization of health services among older people living in two urban neighborhoods of northern Madrid. METHODS: A cross-sectional population-based study. It is studied a cohort of 1327 individuals ≥ 65 years, stratified by age and sex. Nine utilization indicators were defined. For each indicator frequencies and the association of each with the other variables were calculated by multivariate analysis. RESULTS: The distribution of indicators expressed as a percentage of the user population is: GP appoiments/month 64.8% (95%CI 62.3 to 67.4); nursing appoiments/month 44.6% (95% CI 41.2 to 47.2); home medical visits/month 3.1% (95%CI 2.2 to 4.1); home nursing visits/month 3% (95%CI 2.1 to 3.9); hospitalization/year 16.4% (95%CI 14.4 to 18.4); appoiments rheumatologist/orthopedic/year 25.1% (95%CI 22.7 to 27.4); physiotherapist appoiments/year 12.9% (95% CI 11.1 to 14.7); podiatrist appoiments/year 30.6% (95%CI 28.1 to 33.1) and polypharmacy (≥5 drugs) 55.7% (95% CI 53 to 58.4). Comorbidity was the best predictor of health care utilization ranging from OR 4.10 (95%CI: 3.07-5,49) to OR 1.39 (95%CI: 0.97-1.99) in polymedicated and visit the physiotherapist respectively. Cardiovascular disease (OR 1.34; 95%CI 1.03-1,76) and diabetes (OR 1.46; 95%CI: 1.05 -2.02) were independently associated with increased use of family doctor. Dependence was the main determinant for home healthcare (OR 3.38; 95%CI: 1.38-8.28) and nurses (OR 9.71; 95%CI: 4.19-22.48) Mood disorders were associated to polypharmacy (OR 2.06; 95%CI: 1,48-2.86) and to visits to family doctor (OR 1.52; 95%CI: 1,13-2.04). CONCLUSIONS: The comorbidity is the strongest predictor of health services utilization. Cardiovascular diseases and diabetes are independently associated to greater use. Dependence is the main determinant of home care. Mood disorders associated with polypharmacy and increased attendances to the General Practitioner.

OBJETIVO: El envejecimiento de la población española se traduce en un aumento de las prestaciones sanitarias requeridas por la población mayor, por ello conocer la frecuencia de la utilización de los servicios sanitarios de este grupo de edad y analizar sus factores determinantes es de especial interés. El objetivo fue analizar la utilización de servicios sanitarios de la población mayor residente en dos barrios urbanos del norte de Madrid. METODOS: Estudio transversal de base poblacional. Se estudió una cohorte de 1.327 individuos igual o mayor a 65 años, estratificada por edad y sexo. Se definieron 9 indicadores de utilización durante el mes anterio o durante el último año. Para cada indicador se calcularon las frecuencias y la asociación con el resto de variables mediante análisis multivariante. RESULTADOS: la distribución de los indicadores expresada como proporción de la población usuaria fue: consultas médico/mes 64,8% (IC95%:62,3-67,4); consultas enfermería/mes 44,6% (IC95%:41,2-47,2); domicilios médico/mes 3,1% (IC95%:2,2-4,1); domicilios enfermería/mes 3%(IC95%:2,1-3,9); hospitalización/año 16,4% (IC95%:14,4-18,4); consultas reumatólogo/traumatólogo/año 25,1% (IC95%:22,7-27,4); consultas fisioterapeuta/año 12,9% (IC95%:11,1-14,7); consultas podólogo/año 30,6% (IC95%:28,1-33,1) y polimedicados (≥5 fármacos) 55,7% (IC95%: 53-58,4). La comorbilidad fue la variable que mejor predijo la utilización de servicios sanitarios oscilando entre OR 4.10 (IC95%:3.07-5,49) y OR 1,39 (IC95%: 0.97-1.99) para estar polimedicado y visitar al fisioterapeuta respectivamente. Enfermedades cardiovasculares (OR 1,34; IC95%:1.03-1,76) y diabetes (OR 1,46; IC95%:1,05-2,02) se asociaron de forma independiente a mayor utilización del médico de familia. La dependencia fue el principal determinante de atención domiciliaria para el médico (OR 3,38; IC95%: 1,38-8,28) y para enfermería (OR 9.71; IC 95%: 4.19-22.48). Trastornos del ánimo se asociaron a mayor polimedicación (OR 2.06; IC95%: 1,48-2.86) y visitas al médico de familia (OR 1,52; IC 95%:1,13-2.04). CONCLUSIONES: La comorbilidad fue la variable que mejor predijo la utilización de servicios sanitarios. Las enfermedades cardiovasculares y la diabetes se asocian de forma independiente a mayor utilización de servicios. Los trastornos del ánimo se asocian a mayor polimedicación y más visitas al médico de familia.

Calidad del registro del diagnóstico de demencia en atención primaria. La situación en España en el periodo 2002-2011 / Quality of registration of dementia diagnosis in primary care: The situation in Spain in 2002-2011

OBJETIVO: Comprobar el diagnóstico asociado al tratamiento específico para demencia en la historia clínica electrónica de atención primaria (HCE-AP) y analizar los factores asociados a la calidad del registro. MÉTODO: Estudio descriptivo de los pacientes con anticolinesterásicos o memantina registrados en la Base para Investigación Farmacoepidemiológica en atención primaria (BIFAP) 2011: 24.575 pacientes entre 2002 y 2011. Los diagnósticos asociados a la primera prescripción de estos fármacos se agruparon en 5 categorías: «demencia», «alteraciones de memoria», «enfermedades relacionadas con demencia», «procesos intercurrentes» y «códigos de conveniencia». Se calculó la prevalencia de cada categoría por edad y sexo en cada año de estudio (IC 95%) y se analizaron asociaciones y tendencia 2002-2011, utilizando diferencias de proporciones para muestras independientes y regresión logística binaria. RESULTADOS: El 56,5% (IC 95%: 55,8-57,1) de los pacientes tenían asociado código «demencia» a la primera prescripción. Se registró mejor en mujeres (OR: 1,09 [IC 95%: 1,03-1,15]) y al aumentar el tiempo transcurrido (OR: 1,07 [IC 95%: 1,06-1,08] por cada año de seguimiento). Los «códigos de conveniencia» (16,3% [IC 95%: 15,8-16,7]) se utilizaron más en mujeres y ≥ 80 años; las «alteraciones de memoria» (12,4% [IC 95%: 12,0-12,8]), «enfermedades relacionadas» (4,6% [IC 95%: 4,4-4,8]) y «procesos intercurrentes» (10,3% [IC 95%: 9,9-10,6]) más en hombres y < 80 años. De 2002 a 2011 mejoró el uso de «códigos de conveniencia». CONCLUSIONES: Casi la mitad de los pacientes con anticolinesterásicos o memantina no tienen registrado diagnóstico de demencia en su HCE-AP. El registro mejora al aumentar el tiempo de seguimiento. Se requieren mejoras de la HCE-AP, coordinación asistencial adecuada y actitud activa para aumentar la calidad del registro de demencia

OBJECTIVE: To ascertain the diagnosis associated with specific treatment for dementia in the Primary Care Electronic Clinical Record (PC-ECR) and to analyse the factors associated with the quality of registration. METHODS: Descriptive study of patients taking cholinesterase inhibitors or memantine registered in Database for pharmacoepidemiological research in PC (BIFAP) 2011: 24,575 patients between 2002 and 2011. Diagnoses associated with first prescription of these drugs were grouped into 5 categories: 'dementia', 'memory impairment', 'dementia-related diseases', 'intercurrent processes' and 'convenience codes'. We calculated the prevalence of each category by age and sex for each study year (95% CI) and analysed the associations and trend for 2002-2011 using difference in proportions in independent samples and binary logistic regression. RESULTS: A code of 'dementia' was associated with first prescription in 56.5% (95% CI: 55.8-57.1) of PATIENTS: It was higher in women [OR 1.09 (95% CI: 1.03-1.15)] and with increasing follow-up time [OR 1.07 (95% CI: 1.06-1.08) for each year of follow-up]. 'Convenience codes' [16.3% (95% CI: 15.8-16.7)] were coded more frequently in women and in those ≥ 80 years; 'Memory impairment' [12.4% (95% CI: 12.0-12.8)], 'related diseases' [4.6% (95% CI: 4.4-4.8)] and 'intercurrent processes' [10.3% (95% CI: 9.9-10.6)] were used more in men and in persons < 80 years. Between 2002 and 2011 improved the use of 'convenience codes'. CONCLUSIONS: Almost half of the patients taking cholinesterase inhibitors or memantine do not have a diagnosis of dementia registered in their PC-ECR. Registration improves with increasing time of follow-up. Improvements are needed in the PC-ECR, adequate care coordination, and proactive approach to increase the quality of dementia registration

[Quality of registration of dementia diagnosis in primary care: The situation in Spain in 2002-2011]. / Calidad del registro del diagnóstico de demencia en atención primaria. La situación en España en el periodo 2002-2011.

OBJECTIVE: To ascertain the diagnosis associated with specific treatment for dementia in the Primary Care Electronic Clinical Record (PC-ECR) and to analyse the factors associated with the quality of registration. METHODS: Descriptive study of patients taking cholinesterase inhibitors or memantine registered in Database for pharmacoepidemiological research in PC (BIFAP) 2011: 24,575 patients between 2002 and 2011. Diagnoses associated with first prescription of these drugs were grouped into 5 categories: "dementia", "memory impairment", "dementia-related diseases", "intercurrent processes" and "convenience codes". We calculated the prevalence of each category by age and sex for each study year (95%CI) and analysed the associations and trend for 2002-2011 using difference in proportions in independent samples and binary logistic regression. RESULTS: A code of "dementia" was associated with first prescription in 56.5% (95%CI: 55.8-57.1) of patients. It was higher in women [OR1.09 (95%CI: 1.03-1.15)] and with increasing follow-up time [OR1.07 (95%CI: 1.06-1.08) for each year of follow-up]. "Convenience codes" [16.3% (95%CI: 15.8-16.7)] were coded more frequently in women and in those ≥80 years; "Memory impairment" [12.4% (95%CI: 12.0-12.8)], "related diseases" [4.6% (95%CI: 4.4-4.8)] and "intercurrent processes" [10.3% (95%CI: 9.9-10.6)] were used more in men and in persons <80 years. Between 2002 and 2011 improved the use of "convenience codes". CONCLUSIONS: Almost half of the patients taking cholinesterase inhibitors or memantine do not have a diagnosis of dementia registered in their PC-ECR. Registration improves with increasing time of follow-up. Improvements are needed in the PC-ECR, adequate care coordination, and proactive approach to increase the quality of dementia registration.