Subject(s)
Humans , Male , Female , Gram-Positive Bacterial Infections/drug therapy , Gram-Positive Bacterial Infections/epidemiology , Gram-Positive Bacterial Infections/physiopathology , Risk Factors , Anti-Bacterial Agents/therapeutic use , Bone Diseases, Infectious/drug therapy , Microbial Sensitivity Tests , Efficacy/trends , Treatment Outcome , Thrombocytopenia/complicationsSubject(s)
Acetamides/therapeutic use , Anti-Infective Agents/therapeutic use , Fracture Fixation, Internal/adverse effects , Gram-Positive Bacterial Infections/drug therapy , Osteomyelitis/drug therapy , Osteomyelitis/microbiology , Oxazolidinones/therapeutic use , Prosthesis-Related Infections/drug therapy , Aged , Drug Resistance, Multiple, Bacterial , Female , Gram-Positive Bacterial Infections/etiology , Humans , Linezolid , Male , Retrospective StudiesABSTRACT
Objetivo. Estudio y comparación del elastofibroma dorsi y distintas tumoraciones de la región escapular. Material y método. Se ha realizado un estudio retrospectivo de nueve tumoraciones de partes blandas que afectaron a la región escapular, analizando los métodos de diagnóstico y sus diferentes tratamientos. Resultados y conclusiones. De las nueve tumoraciones estudiadas, cinco correspondieron a elastofibroma dorsi, y las cuatro restantes a tumoraciones de diferente estirpe, dos liposarcomas mixoides, un lipoma intramuscular, y una ruptura muscular y hematoma secundario. Aun siendo los elastofibromas raros en la práctica clínica diaria, el conocimiento de las características de esta lesión debería disminuir los diagnósticos erróneos y hacer innecesarias cirugías agresivas y, probablemente, biopsias
Aim. Study and comparison of elastofibroma dorsi and other tumors of the scapular region. Materials and methods. Nine soft-tissue tumors of the scapular region were studied retrospectively to analyze diagnostic methods and treatments. Results and conclusions. Of the nine tumors studied, five were elastofibromata dorsi and the remaining four included two myxoid liposarcomas, one intramuscular lipoma, and a muscle tear with secondary hematoma. Although elastofibromas are rare in daily clinical practice, familiarity with the characteristics of this lesion would reduce erroneous diagnoses and reduce the need for biopsy and aggressive surgery
Subject(s)
Female , Adult , Middle Aged , Humans , Fibroma/pathology , Scapula/pathology , Soft Tissue Neoplasms/pathology , Retrospective Studies , Diagnosis, Differential , Elastic Tissue/pathologySubject(s)
Abscess/diagnosis , Hip Joint/diagnostic imaging , Mycobacterium tuberculosis/isolation & purification , Thigh/microbiology , Tuberculosis, Osteoarticular/diagnosis , Abscess/microbiology , Abscess/therapy , Antitubercular Agents/therapeutic use , Diagnosis, Differential , Hip Joint/microbiology , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Orthopedic Procedures/methods , Radiography , Soft Tissue Neoplasms/diagnosis , Thigh/diagnostic imaging , Thigh/pathology , Treatment Outcome , Tuberculosis, Osteoarticular/microbiologyABSTRACT
No disponible
Subject(s)
Middle Aged , Male , Humans , Thigh , Tuberculosis, Osteoarticular , Orthopedic Procedures , Treatment Outcome , Mycobacterium tuberculosis , Antitubercular Agents , Diagnosis, Differential , Abscess , Magnetic Resonance Imaging , Hip Joint , Soft Tissue NeoplasmsABSTRACT
The objective of this study was to evaluate the diagnostic value of fat-suppressed T2-weighted (FS-T2) images or short tau inversion recovery (STIR) imaging in distinguishing lipoma from lipoma-like subtype of well-differentiated liposarcoma. Spin-echo T1-weighted and STIR or fat-suppression T2-weighted sequences were performed in 60 lipomas and 32 lipoma-like well-differentiated liposarcomas, histologically proven, looking for thick septa or nodules in T1-weighted images and linear, nodular, or amorphous hyperintensities on FS-T2/STIR sequences. Fourteen lipomas (23.3%) showed thick septa and/or nodules on T1, whereas on FS-T2 or STIR sequences only seven (11.7%) displayed hyperintense nodules and/or septa. All well-differentiated liposarcomas contained these signs on FS-T2 or STIR sequences. The presence of hyperintense septa or nodules in a predominantly lipomatous tumor on FS-T2/STIR sequences helps to differentiate malignant tumors from lipomas. Employing the presence of hyperintense nodules and/or septa as criteria of malignancy specificity was 76.6% and sensitivity 100%. Overdiagnoses of well-differentiated liposarcoma can occur due to the presence of non-lipomatous areas within lipomas.
Subject(s)
Artifacts , Image Enhancement/methods , Image Processing, Computer-Assisted/methods , Lipoma/diagnosis , Liposarcoma/diagnosis , Magnetic Resonance Imaging/methods , Soft Tissue Neoplasms/diagnosis , Adipose Tissue/pathology , Connective Tissue/pathology , Diagnosis, Differential , Extremities , Humans , Lipoma/pathology , Liposarcoma/pathology , Retrospective Studies , Sensitivity and Specificity , Soft Tissue Neoplasms/pathologyABSTRACT
INTRODUCTION: The diagnosis and treatment of posterior plagiocephaly is one of the most controversial aspects of craniofacial surgery. PATIENTS AND METHODS: The purpose of this study is to describe a recent increase in the incidence of occipital plagiocephaly without synostosis in our hospital during the last 6 months. The shift in the referral patterns is roughly contemporaneous with the American Academy of Pediatrics recommendations regarding infant sleep position. The temporal coincidence of this increase with the recommendation to avoid the prone sleeping position, to reduce the risk of sudden infant death syndrome, suggests a possible causal relationship. If the association is causal, education regarding the need of head position rotation coupled with that for sudden infant death syndrome should obviate positional occipital plagiocephaly. CONCLUSIONS: The feature of true lambdoid synostosis versus those of deformational plagiocephaly secondary to positional molding are inadequately described in the literature and poorly understood; the differential diagnosis is important in relation to a conservative diagnostical and therapeutical intervention in patients with positional molding.
Subject(s)
Occipital Bone/injuries , Supine Position , Craniosynostoses/diagnosis , Diagnosis, Differential , Female , Humans , Incidence , Infant , Male , Occipital Bone/abnormalities , Occipital Bone/pathology , Patient Education as Topic , Pregnancy , Spain/epidemiology , Sudden Infant Death/prevention & controlABSTRACT
We describe a 14 year old male, diagnosed of Ewing sarcoma in left astragalus. We performed two 201-Thallium scan for evaluating the response to chemotherapy (before and after the treatment). The scan performed after chemotherapy showed patchy uptake in astragalus, calcaneus and some joints of the foot. The following radiology and scintigraphy diagnosed a reflex sympathetic dystrophy in the left foot due to disuse of the limb. The 201-Thallium overestimated viability of the tumour for this reason. We must discard the presence of this kind of associated pathology in order that they could be cause of false positives.
Subject(s)
Bone Neoplasms/diagnostic imaging , Radiopharmaceuticals , Reflex Sympathetic Dystrophy/diagnostic imaging , Sarcoma, Ewing/diagnostic imaging , Talus/diagnostic imaging , Thallium Radioisotopes , Adolescent , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bone Neoplasms/complications , Bone Neoplasms/drug therapy , Calcaneus/diagnostic imaging , Diagnosis, Differential , False Positive Reactions , Humans , Male , Neoplasm Invasiveness/diagnostic imaging , Radionuclide Imaging , Radiopharmaceuticals/pharmacokinetics , Reflex Sympathetic Dystrophy/etiology , Sarcoma, Ewing/complications , Sarcoma, Ewing/drug therapy , Thallium Radioisotopes/pharmacokineticsABSTRACT
The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicenter, randomized double-blind study. The study was carried out at 5 centers and involved a total of 143 patients with endoscopically documented active duodenal ulcer. The patients received either famotidine (1 40 mg tablet at night) or ranitidine 2 150 mg tablets at night). Endoscopic examinations were performed at 4 and 6 weeks of active treatment. Day and nocturnal pain were also monitored, and the laboratory and clinical profiles evaluated. One hundred and thirty-three patients fulfilled the evaluation criteria (66 patients in the famotidine group and 67 in the ranitidine group). Healing rates at weeks 4 or 6 of treatment showed no significant differences between the famotidine group and the ranitidine group. The healing rates were 78% at week 4 and 96% at week 6 in the famotidine group, and 76% at week 4 and 95% at week 6 in the ranitidine group. Similar results were observed in both treatment groups with regard to pain resolution, decrease in antacid intake and safety profile.
Subject(s)
Anti-Ulcer Agents/administration & dosage , Duodenal Ulcer/drug therapy , Ranitidine/administration & dosage , Thiazoles/administration & dosage , Adult , Anti-Ulcer Agents/therapeutic use , Clinical Trials as Topic , Double-Blind Method , Drug Administration Schedule , Famotidine , Female , Humans , Male , Middle Aged , Multicenter Studies as Topic , Random Allocation , Ranitidine/therapeutic use , Thiazoles/therapeutic useABSTRACT
In a preliminary study of the immunological aspects of intestinal inflammatory disease we found an immunological deficit of T helper lymphocytes, decreased monocytes and chemotaxis and poor response to nonspecific mitogen stimulus. Based on these findings, the study was repeated in the same patients three years later to confirm the evolution of this deficit. Recuperation was observed in the cases in which the disease evolved favorably, suggesting that certain aspects of the immune disorder might be secondary.
Subject(s)
Colitis, Ulcerative/immunology , Crohn Disease/immunology , Follow-Up Studies , Humans , Immunity, Cellular , Inflammatory Bowel Diseases/immunology , Lymphocytes/immunologyABSTRACT
The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicentre, randomized, double-blind study. The study was carried out in five centres which included a total of 143 patients with endoscopically documented active duodenal ulcer. The patients received either famotidine (one tablet of 40 mg at night) or ranitidine (two tablets of 150 mg at night). Endoscopic examinations were performed at 4 and 6 weeks of active treatment. Daytime and nocturnal pain were also monitored, and the laboratory and clinical profiles evaluated. One hundred and thirty-three patients fulfilled the evaluation criteria (66 patients in the famotidine group and 67 in the ranitidine group). Healing rates at 4 or 6 weeks of treatment showed no significant differences between the famotidine and ranitidine groups. The healing rates were 80% at week 4 and 97% at week 6 in the famotidine group, and 77% at week 4 and 96% at week 6 in the ranitidine group. Similar results were observed in both treatment groups with regard to pain resolution, decrease in antacid intake and safety profile.
Subject(s)
Duodenal Ulcer/drug therapy , Famotidine/therapeutic use , Ranitidine/therapeutic use , Adult , Aged , Antacids/administration & dosage , Antacids/therapeutic use , Double-Blind Method , Famotidine/adverse effects , Female , Humans , Male , Middle Aged , Ranitidine/adverse effects , Smoking/physiopathologyABSTRACT
The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicenter, randomized double-blind study. The study was carried out in 5 centers which included a total of 143 patients with endoscopically documented active duodenal ulcer. The patients received either famotidine (1 tablet of 40 mg at night) or ranitidine (2 tablets of 150 mg at night). Endoscopic examinations were performed at 4 and 6 weeks of active treatment. Day and nocturnal pain were also monitored and the laboratory and clinical profiles evaluated. One hundred and thirty-three patients fulfilled the evaluation criteria (66 patients in the famotidine group and 67 in the ranitidine group). Healing rates at weeks 4 or 6 of treatment showed no significant differences between the famotidine and the ranitidine groups. The healing rates were 79% at week 4 and 96% at week 6 in the famotidine group, and 77% at week 4 and 95% at week 6 in the ranitidine group. Similar results were observed in both treatment groups with regard to pain resolution, decrease in antacid intake and safety profile.
Subject(s)
Anti-Ulcer Agents/administration & dosage , Duodenal Ulcer/drug therapy , Ranitidine/administration & dosage , Thiazoles/administration & dosage , Adult , Anti-Ulcer Agents/therapeutic use , Double-Blind Method , Drug Administration Schedule , Famotidine , Female , Humans , Male , Multicenter Studies as Topic , Random Allocation , Ranitidine/therapeutic use , Thiazoles/therapeutic use , Time Factors , Wound HealingSubject(s)
Hyperparathyroidism/etiology , Pancreatitis/etiology , Acute Disease , Adult , Aged , Female , Humans , MaleSubject(s)
Cysts/complications , Hemangioma/complications , Liver Diseases/complications , Liver Neoplasms/complications , Cysts/diagnosis , Cysts/diagnostic imaging , Female , Hemangioma/diagnosis , Hemangioma/diagnostic imaging , Humans , Liver Diseases/diagnosis , Liver Diseases/diagnostic imaging , Liver Neoplasms/diagnosis , Liver Neoplasms/diagnostic imaging , Middle Aged , Radionuclide Imaging , Tomography, X-Ray Computed , UltrasonographySubject(s)
Hemangioma, Cavernous/pathology , Liver Neoplasms/pathology , Celiac Artery/diagnostic imaging , Hemangioma, Cavernous/diagnostic imaging , Hemangioma, Cavernous/surgery , Hepatic Artery/diagnostic imaging , Humans , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/surgery , Male , Middle Aged , RadiographyABSTRACT
In a review of our experience with the extraction of foreign bodies using the fiberendoscope in 57 patients who ingested true foreign bodies and had food bolus impaction, we found 17 of the foreign bodies to be big metallic wires. The extraction technique used and the complications as a result of the object or the technique are given herein.
Subject(s)
Duodenum , Endoscopy , Esophagus , Foreign Bodies/therapy , Stomach , Adolescent , Adult , Aged , Deglutition Disorders/etiology , Esophagoscopy , Fiber Optic Technology , Foreign Bodies/complications , Foreign Bodies/diagnostic imaging , Humans , Middle Aged , RadiographyABSTRACT
A case of an ulcer of the rectum in a 20-year-old patient with rectal pain and rectal bleeding is reported. Histological examination of the endoscopic biopsy showed the presence of gastric or fundic mucosa. The patient was treated with Cimetidine and alkaline drugs, with positive results. Ulcer cicatrization was verified at subsequent endoscopic examinations, and biopsies obtained at different levels of the colon revealed a normal histological picture.