ABSTRACT
Resumen Los lipomas son considerados los tumores de origen mesenquimatoso más comunes del tejido blando; de ellos el 13% del total se ubican en cabeza y cuello, pero es difícil encontrarlos en la región oral y maxilofacial. La localización más común de lipomas dentro de la región oral y maxilofacial ha sido reportada en la mucosa bucal, lengua y piso de boca. Los lipomas son neoplasias que se presentan típicamente como una masa suave, de superficie lisa, nodular, amarillenta y asintomática. Histopatológicamente, el lipoma clásico asemeja un tejido normal adiposo y tiene múltiples variantes. Este artículo presenta el reporte de caso de un lipoma oral extenso en un paciente femenino de 46 años de edad en la mucosa yugal, tratado quirúrgicamente con adecuada evolución. Asimismo se realiza la revisión de literatura con sus variantes histopatológicas.
Abstract Lipomas are considered the most frequent mesenchymal tumors of soft tissue, 13% are located in head and neck but it´s difficult to find them in the oral and maxillofacial region. The most common location of lipomas within the oral and maxillofacial region has been reported in the buccal mucosa, tongue and floor of the mouth. Lipomas are neoplasias that typically present as a soft, smooth-surfaced, nodular, yellowish, and asymptomatic mass. Histopathologically, the classical lipoma resembles normal adipose tissue and it has multiple variants. This article presents a case report of a relatively large oral classical lipoma in a 46 year-old woman on mandibular buccal vestibule, along with a review of the literature and its histopatho-logical variants.
Subject(s)
Humans , Female , Middle Aged , Mouth Neoplasms , Lipoma/diagnosis , MexicoABSTRACT
The congenital granular cell lesion most commonly occurs on the maxillary or mandibular alveolus of neonates. Extra-alveolar congenital granular cell lesion is exceptionally rare, with only 10 cases reported. Two additional cases occurring on the tongue are presented with a description of the clinical, histopathologic, and immunohistochemical features. The differential diagnosis is discussed, and the literature reviewed.
Subject(s)
Granular Cell Tumor/congenital , Tongue Neoplasms/congenital , Diagnosis, Differential , Female , Granular Cell Tumor/pathology , Granular Cell Tumor/surgery , Humans , Infant, Newborn , Tongue Neoplasms/pathology , Tongue Neoplasms/surgeryABSTRACT
Desde las primeras épocas de la historia, el hombre ha intentado restituir la función de los órganos dentarios perdidos. El sueño de la odontología es sustituir los materiales que se usan hoy en día por otros de origen biológico, basados en células que tengan las mismas características o semejantes a las naturales para poder así regenerar o reparar los tejidos perdidos. Las publicaciones recientes enfatizan el uso de las células troncales inducidas a pluripotencia (iPSC por sus siglas en inglés), como la posible solución al controvertido uso de células madre y la obtención de ellas; ésta es sólo una de las muchas posibilidades que se plantean para las futuras investigaciones; sin embargo, debido a que es la más acertada, la aplicación de estas técnicas en el ámbito odontológico es la forma más cercana de poder llegar a restituir los tejidos perdidos. Es así como la bioingeniería dental se abre a nuevos horizontes, esperando obtener mejores alcances en beneficio de la salud de nuestra población.
Subject(s)
Humans , Stem Cells/physiology , Tissue Engineering/trends , Bone Regeneration/physiology , Wound Healing/physiology , Dental Research , Tooth/embryologyABSTRACT
Two cases of leiomyomatous hamartoma (LH) in patients of Latin ancestry are reported here. The first lesion was detected on the incisive papilla of a 19-year-old woman; this is an unusual age because these lesions are commonly observed during the first years of life. The second lesion found on the middle-dorsum of the tongue was observed in a 5-month-old boy. The diagnosis was based on the histopathological appearance and confirmed by immunohistochemistry with positivity for smooth muscle actin, muscle-specific actin, S-100 protein and desmin. To date, only 16 cases have been reported in the English-language literature. Controversial epidemiological data, histogenesis, clinical/histopathological features, and differential diagnosis are discussed herein.
Subject(s)
Gingival Diseases/pathology , Hamartoma/pathology , Tongue Diseases/pathology , Adult , Diagnosis, Differential , Female , Gingival Diseases/surgery , Hamartoma/surgery , Humans , Infant , Leiomyoma/pathology , Leiomyoma/surgery , Male , Tongue Diseases/surgeryABSTRACT
Dejando de lado la patología infecciosa y traumática, la gran mayoría de las patologías odontológicas, tienen una base genética, en algunas de ellas identificada, en otras no. Para los estomatólogos es de gran importancia conocer las característicasclínicas y el tipo de alteración que acompañan a los síndromes de etiología genética, para poder ofrecer a los pacientes un tratamiento apropiado y multidisciplinario.Objetivo: Búsqueda intencional y descripción de la patología bucal en pacientes con diversas enfermedades genéticas.Diseño del estudio: Se realizó un estudio observacional y descriptivo reuniendo a 62 pacientes de la consulta de Genética del Instituto Nacional de Rehabilitación durante 4 meses. Se tomaron en cuenta, además de las manifestaciones bucales y la enfermedad genética relacionada a las mismas, el sexo, la edad, la presencia o no de consanguinidad, y endogamia, así como la localización de la manifestación bucal. La mayoría de los pacientes que presentan patología genética no tienen tratamiento curativo, pero sí podrán realizarse otros tratamientos para mejorar su calidad de vida, entre estos se cuentan los diversos tratamientos odontológicos.Resultados: Los padecimientos diagnosticados con mayor frecuencia fueron neuropatías periféricas hereditarias, displasias esqueléticas, malformaciones de miembros y distrofias musculares. Se describieron diversas manifestaciones que fueron registradas y agrupadas de acuerdo a su localización
Without considering infectious and traumatic diseases, the great majority of oral cavity diseases have a genetic base, in some cases identifiable, in others not. For the stomatologists it is of great importance to know the clinical characteristics and type of alteration that go with genetic etiology syndromes to be able to offer patients an adequate multidisciplinary treatment.Objective: Intentional search and description of oral pathology in patients with diverse genetic diseases.Study design: An observational and descriptive 4 month study of 62 patients from the Genetics Department of the NationalInstitute of Rehabilitation, was done. Taken into consideration, aside from oral manifestations and genetic disease, were age, sex, consanguinity and inbreeding. The majority of patients who have genetic pathology do not have curative treatment, but they can receive other treatments to improve their quality of life, among these are dental treatments.Results: The more common diseases we found were hereditary peripheral neuropathies, skeletal dysplasias, limb malformationand muscular dystrophies. Diverse features were described, registered and grouped according to their location.Conclusions: Presently it is important to look for the genetic etiology of all diseases to seek specific treatments and prevent them. This will change the practice of medicine and dentistry
Subject(s)
Male , Female , Child, Preschool , Child , Adolescent , Adult , Humans , Genetic Diseases, Inborn/genetics , Mouth Diseases/genetics , Consanguinity , Genetic Diseases, Inborn/classification , MexicoABSTRACT
UNLABELLED: Without considering infectious and traumatic diseases, the great majority of oral cavity diseases have a genetic base, in some cases identifiable, in others not. For the stomatologists it is of great importance to know the clinical characteristics and type of alteration that go with genetic etiology syndromes to be able to offer patients an adequate multidisciplinary treatment. OBJECTIVE: Intentional search and description of oral pathology in patients with diverse genetic diseases. STUDY DESIGN: An observational and descriptive 4 month study of 62 patients from the Genetics Department of the National Institute of Rehabilitation, was done. Taken into consideration, aside from oral manifestations and genetic disease, were age, sex, consanguinity and inbreeding. The majority of patients who have genetic pathology do not have curative treatment, but they can receive other treatments to improve their quality of life, among these are dental treatments. RESULTS: The more common diseases we found were hereditary peripheral neuropathies, skeletal dysplasias, limb malformation and muscular dystrophies. Diverse features were described, registered and grouped according to their location. CONCLUSIONS: Presently it is important to look for the genetic etiology of all diseases to seek specific treatments and prevent them. This will change the practice of medicine and dentistry.
