ABSTRACT
We present a case of craniofacial dermoid cyst in a 50-year-old female. The patient's complaint was persistent refractory headaches with no other significant neurological symptoms. Diagnostic imaging revealed the presence of a lesion in the left fronto-zygomatic region. Surgical intervention involved a craniotomy that led to a successful excision of the dermoid cyst. The diagnosis was subsequently confirmed by histopathological analysis. This case underscored the importance of considering DC as a potential diagnosis for any craniofacial lesion, given their diverse presentations and associated complications.
ABSTRACT
Sellar xanthogranulomas are extremely rare intracranial lesions, particularly in pediatric patients, and their diagnostic and therapeutic challenges prompt thorough investigation. We describe a case of a two-year-old toddler diagnosed with sellar xanthogranuloma, highlighting the challenges encountered in its diagnosis and management. The child presented with symptoms, including headache, ptosis of the left eye, and neurological deficits. Brain computed tomography (CT) and magnetic resonance imaging (MRI) revealed a hypodense sellar lesion. The patient underwent a left pterional craniotomy for resection of the mass. Histopathological examination suggested the diagnosis of sellar xanthogranuloma, characterized by foamy macrophages, giant cells, lymphocytic infiltrates, fibrous proliferation, necrotic detritus, and hemosiderin deposits. Further diagnostic precision was achieved through immunohistochemical staining, including CD1a and langerin, which successfully ruled out the possibility of Langerhans cell histiocytosis (LCH), reinforcing the diagnosis of sellar xanthogranuloma. The successful surgical resection of the lesion led to a favorable outcome, evidenced by the significant alleviation of symptoms as well as the restoration of normal neurological function. Post-operative assessments demonstrated a marked improvement in the patient's quality of life, and there were no observed complications or recurrence of the lesion during the follow-up period. In summary, our case report not only highlights the rarity and diagnostic challenges of sellar xanthogranulomas but also emphasizes the importance of collaborative medical expertise in achieving accurate diagnosis and successful therapeutic outcomes in pediatric patients. The successful management of this case offers valuable insights into the clinical presentation, diagnostic complexities, and treatment strategy of sellar xanthogranulomas, further enriching our understanding of this uncommon intracranial pathology.
ABSTRACT
Cerebello-pontine angle (CPA) tumors account for only less than 10 % of intracranial tumors, it usually affects children at a young age with the midline being the most favorable location. Our adult patient demonstrated a very unusual site for medulloblastoma at the CPA. Less than 50 cases all around the world have been reported in the English literature for Medulloblastoma to be located at the CPA, and most of them in pediatric age group. We report a 43 year old female patient who presented to our neurosurgical ward in Jerusalem with a 4 months history of progressive decreased hearing at the left side, accompanied with tinnitus, dizziness, and imbalance on walking. Medulloblastoma at the CPA was one of the differential diagnosis and was confirmed at our histopathology unit after gross total resection of the tumor, the surgery followed by radiotherapy and the patient was well after 9 months after procedure. MB-CPA is a relatively rare tumor, and the early diagnosis make a difference in the management, prognosis, and outcomes, so it should be considered as a differential diagnosis of a lesion of the CPA.
ABSTRACT
BACKGROUND: Clear cell sarcoma is a very rare malignant tumor originating from neural crest cells, the tumor most commonly affects the lower limbs but there have been few cases reported to affect the trunk and para spinal area. Patients with Para spinal sarcoma have a variety of clinical presentations and a variable prognosis depending on several prognostic factors including tumor size. CASE PRESENTATION: A 14-year-old male patient presented with paraplegia for one month duration and he was diagnosed later on to have a paraspinal clear cell sarcoma at D12-L1 level. A wide local excision was made and patient was referred for oncology treatment. However, the patient came back to the same hospital after two months due to the recurrence of the tumor at the same site. CONCLUSION: Clear cell sarcoma, although rare, can affect the spine and present with weakness, paraplegia and backache. It also affects people from all age groups and can have a high metastatic rate and a high recurrence rate.
ABSTRACT
INTRODUCTION: Cerebellar liponeurocytoma is a rare tumor of the central nervous system occurring mainly in the posterior fossa, which shows neuronal and variable astrocytic differentiation, along with foci of lipomatous differentiation. CASE PRESENTATION: Herein, we describe a 50-year-old female patient who presented to the hospital complaining of headache, tinnitus, and vertigo with positive cerebellar signs. MRI revealed a left cerebellar tumor. After tumor resection, histological examination and immunohistochemistry were done and the diagnosis of cerebellar liponeurocytoma was confirmed. DISCUSSION: Liponeurocytoma may be mistaken as a medulloblastoma with lipidized cells or a lipomatous ependymoma. Histopathological examination, reinforced by immunohistochemistry and electron microscopy, are required to distinguish between these entities. The rarity of this tumor and paucity of pertinent information regarding its biological potential and natural history have resulted in the application of various treatment modalities. CONCLUSION: Liponeurocytoma is a rare benign tumor with cerebellum is the typical site for it. Although surgery is the treatment of choice; however, postoperative radiotherapy may have a role in case of incomplete tumor resection or recurrence.
