ABSTRACT
PURPOSE: To evaluate the volume reduction rate (VRR) of thyroid nodules over a long period of time after radiofrequency (RF) ablation treatment in both solid and mixed nodules; to determine ablation parameters; and to evaluate complications and success rates and safety of RF ablation. MATERIAL AND METHODS: In this prospective study, 24 patients (83% females and 17% males; age 50.17 ± 13.6 years) underwent ultrasound-guided percutaneous RF ablation of benign thyroid nodules with radiologic follow-up at 1, 3, 6, 12, 24, and 36 months after treatment. All patients presented with compressive or cosmetic complaints and with Thyroid Imaging Reporting and Data System 1 or 2 nodules under ultrasound and were confirmed to be Bethesda Category II after 2 fine-needle aspirations. RESULTS: A total of 24 nodules (54.2% solid, 37.5% solid predominance, and 8.3% cystic predominance) were included in this study. Significant results in VRR (%) were found at 24 months and 36 months of 69.92 ± 19.23 and 76.84 ± 15.92, respectively. Furthermore, a logarithmic relationship was found when VRR was plotted over time, in both solid and mixed nodules. No correlations were found with any of the ablation parameters. The success rate reached 72.22% at 12 months, and the total complication rate was 16.67% (12.5% minor complications and 4.2% major complications-1 laryngeal nerve palsy), reaching an 83.3% safety. CONCLUSIONS: RF ablation can be an alternative treatment modality in the management of benign symptomatic thyroid nodules. The results show that it is a safe and effective treatment if trans-isthmic approach and moving-shot techniques are correctly followed.
Subject(s)
Radiofrequency Ablation , Thyroid Nodule/surgery , Adult , Female , Humans , Male , Middle Aged , Postoperative Complications/etiology , Prospective Studies , Radiofrequency Ablation/adverse effects , Risk Factors , Thyroid Nodule/diagnostic imaging , Time Factors , Treatment Outcome , Ultrasonography, InterventionalABSTRACT
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Subject(s)
Humans , Drainage/methods , Pancreatic Pseudocyst/surgery , Cystostomy , Gastrostomy , Jejunostomy , Octreotide/therapeutic useABSTRACT
Los tumores tipo oat cell localizados en la vía biliar principal son extremadamente raros. Desbribimos el caso de un paciente de 76 años que presentaba una ictericia de piel y mucosas de 15 días de evolución sin síndrome constitucional, diagnosticado de tumoración en porción media de colédoco. Tras la resección quirúrgica, la anatomía patológica reveló el diagnóstico de carcinoma de células pequeñas tipo oat cell. El tratamiento de estos tumores es multidisciplinario y se instaura tras la cirugía tratamiento con quimio y radioterapia (AU)
Oat cell tumors in the common bile duct are extremely rare. We describe the case of a 76-year-old man with skin and mucous jaundice of 15 days' duration without constitutional syndrome. A tumor was diagnosed in the mid portion of the common bile duct. After surgical resection, pathological analysis revealed small-cell (oat cell) carcinoma. The treatment of these tumors is multidisciplinary. Surgery is followed by chemo- and radiotherapy (AU)
Subject(s)
Male , Middle Aged , Humans , Carcinoma/complications , Carcinoma/diagnosis , Tomography, Emission-Computed/methods , Cholecystectomy/methods , Cholangiography/methods , Bile Duct Neoplasms/complications , Bile Duct Neoplasms/diagnosis , Bile Duct Neoplasms/surgery , Common Bile Duct/pathology , Common Bile Duct/surgery , Abdomen , Common Bile Duct , Carcinoma, Small Cell/complications , Carcinoma, Small Cell/surgery , Carcinoma, Small Cell , Adenoma, Bile DuctABSTRACT
Oat cell tumors in the common bile duct are extremely rare. We describe the case of a 76-year-old man with skin and mucous jaundice of 15 days' duration without constitutional syndrome. A tumor was diagnosed in the mid portion of the common bile duct. After surgical resection, pathological analysis revealed small-cell (oat cell) carcinoma. The treatment of these tumors is multidisciplinary. Surgery is followed by chemo- and radiotherapy.
