ABSTRACT
The complex of climatic and geographical conditions of the Arctic determines the high intensity of the polysystem adaptive response of the organism, the duration of which is additionally influenced by individual genetic characteristics, social conditions, psychological and work loads. Taking into account the relevance of timely prevention and early diagnosis of stress-induced somatic pathology in EMERCOM employees working in unfavorable climatic and geographical zones, the authors evaluated the informative value of determining the level of steroid hormones and insulin as laboratory markers of adaptation to Arctic conditions. The expediency of developing objective criteria for the interpretation of the insulin/cortisol index and studying the informativeness of the 17ONprogesterone level as the earliest marker of adaptation to unfavorable climatic and geographical conditions of the Arctic is substantiated.
Subject(s)
Hydrocortisone , Insulins , Adaptation, Physiological , Arctic Regions , Biomarkers , HumansABSTRACT
Selection of inhalation anaesthetic when low-flow anaesthesia with automated control. A comparative evaluation of low-flow (0,5 l/min) and inhalation anaesthesia with sevoflurane and desfluranom with automated control of the concentration of inhaled anaesthetic on the exhale (Et-control), with the use of advanced monitoring in 76 patients operated on for the pathology of the spine and spinal cord is given. It was found that when using continuous measuring the achievement of the target concentration of the anaesthetic sevoflurane is faster in the group. Total consumption of desflurane was two times higher. Hemodynamic, SPI index were stable at all stages of the operation in both groups.
