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1.
Tsitologiia ; 50(6): 528-34, 2008.
Article in Russian | MEDLINE | ID: mdl-18727404

ABSTRACT

Distributions of nuclear morphology anomalies in transplantable rabdomiosarcoma RA-23 cell populations were investigated under effect of ionizing radiation from 0 to 45 Gy. Internuclear bridges, nuclear protrusions and dumbbell-shaped nuclei were accepted for morphological anomalies. Empirical distributions of the number of anomalies per 100 nuclei were used. The adequate model of reentrant binomial distribution has been found. The sum of binomial random variables with binomial number of summands has such distribution. Averages of these random variables were named, accordingly, internal and external average reentrant components. Their maximum likelihood estimations were received. Statistical properties of these estimations were investigated by means of statistical modeling. It has been received that at equally significant correlation between the radiation dose and the average of nuclear anomalies in cell populations after two-three cellular cycles from the moment of irradiation in vivo the irradiation doze significantly correlates with internal average reentrant component, and in remote descendants of cell transplants irradiated in vitro - with external one.


Subject(s)
Cell Nucleus/pathology , Cell Nucleus/radiation effects , Models, Statistical , Rhabdomyosarcoma/ultrastructure , Animals , Cell Line, Tumor , Dose-Response Relationship, Radiation , Gamma Rays , Interphase/radiation effects , Neoplasm Transplantation , Rats , X-Rays
2.
Mikrobiologiia ; 76(3): 390-404, 2007.
Article in Russian | MEDLINE | ID: mdl-17633415

ABSTRACT

A laboratory model of a cyano-bacterial mat with mineral layers of carbonates was used to examine the dynamics of the transformation of calcium-magnesium carbonate under the conditions of a soda lake. The activity of various organisms of the cyanobacterial community results in conditions under which the Ca-Mg carbonate precipitate undergoes changes. The crystal lattice of the initial carbonate is restructured; its mineralogical composition changes depending on the conditions of the mat. In magnesium calcites, which are formed under such low-temperature conditions, a rudimentary cation adjustment can occur with the formation of dolomite domains. These experiments confirm the hypothesis that the dolomite found in stromatolites is of a secondary origin and can be formed in the course of transformation of Ca-Mg carbonates under alkaline conditions in an alkaliphilic cyanobacterial community.


Subject(s)
Calcium Carbonate/chemistry , Cyanobacteria/metabolism , Magnesium/chemistry , Biomass , Chemical Precipitation , Cyanobacteria/ultrastructure , Evolution, Chemical , Fresh Water , Geologic Sediments/chemistry , Geologic Sediments/microbiology , Microscopy, Electron , Microscopy, Electron, Scanning
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