ABSTRACT
The paper is concerned with the results of a long-term study of 16 children with a verified diagnosis of Reiter's syndrome. Preceding factors, the clinical symptom complex, laboratory findings and the evolution of the disease were described. Emphasis was placed on the necessity of early diagnosis and adequate therapy including antiinflammatory drugs and antibiotics to prevent serious complications, especially of the eyes.
Subject(s)
Arthritis, Reactive/diagnosis , Adolescent , Anti-Inflammatory Agents/therapeutic use , Arthritis, Juvenile/diagnosis , Arthritis, Reactive/drug therapy , Child , Child, Preschool , Diagnosis, Differential , Female , Humans , Infant , MaleSubject(s)
Penicillamine/adverse effects , Prednisolone/administration & dosage , Serositis/chemically induced , Stevens-Johnson Syndrome/drug therapy , Thrombocytopenia/chemically induced , Arthritis, Juvenile/complications , Arthritis, Juvenile/drug therapy , Aspirin/administration & dosage , Child , Female , Humans , Penicillamine/administration & dosage , Serositis/drug therapy , Thrombocytopenia/drug therapyABSTRACT
Juvenile rheumatoid arthritis (JRA) in the Union of Soviet Socialist Republics (USSR) and the United States (USA) shows a remarkable similarity in age of disease onset, subtype onset, frequency, and most laboratory measurements. There is variation in the therapeutic approach with heavier reliance on aspirin in the USA. The evolution of JRA from onset subtype to final subtype over 5 years was the same in both groups and was independent of the type of therapy.
