[Rheologic properties of some pharmaceutical excipients in drug forms and cosmetic preparation technology].

The establishment of mechanisms and principles of the formation of deformation (fracture) of spatial structure of bentonite solutions and various solutions and disperse systems is one or the most important problems of modern pharmaceutical technology. The article presents the results of a long-term research of influence of high-molecular compounds and surfactants on the properties of designed dosage drug forms and cosmetic preparation. Research data, as the basis for drug combinations "gel" with dekamitoksin, extract Aesculus hippocastanum L and probiotics.

[Echocardiographic diagnosis of the origin of the aorta and pulmonary artery from the right heart ventricle]. / Ekhokardiograficheskaia diagnostika otkhozhdeniia aorty i legochnoi arterii ot pravogo zheludochka serdtsa.

The origin of the aorta and pulmonary artery from the right ventricle is a congenital heart disease whose anatomical and echocardiographic criteria are the object of wide current discussion. The classification of the disease has been developed at the Bakulev Institute of Cardiovascular Surgery, USSR AMS. It is based on identification of the anatomical differences in the types of origin of the aorta and pulmonary artery from the right ventricle (RV OAPA). The present research was devoted to the study of the possibilities of echocardiography in the differential diagnosis of the types of the anomaly in the RV OAPA complex and the possibilities of noninvasive differential diagnosis of RV OAPA and adjacent anomalies of the conotruncus. The results of the study allow the conclusion that location of intracardiac structures with purposeful use of ultrasonic projections provides the possibility of making the differential diagnosis of the types of the anomaly in the RV OAPA complex and that the obtained echocardiographic criteria may serve for establishing the differential diagnosis of RV OAPA and other congenital anomalies of the conotruncus.

[Propionic acid cocci and their taxonomic position]. / Propionovokislye kokki i ikh sistematicheskoe polozhenie.

In order to determine the taxonomic position of propionic cocci, the authors studied their morphological, cultural and biochemical properties, the fatty acid composition of cells, and established the degree of homology for the DNAs of cocci and classical propionic bacteria using the method of molecular hybridization. The cocci were found to have the activities of catalase and superoxide dismutase which were higher than in the studied propionic bacteria. The propionic cocci and propionic bacteria were shown to be similar in terms of their fatty acid composition and to contain the C15-saturated acid in the form of anteiso isomer as the main type of fatty acids. Their fatty acid composition was most similar to that of the species Propionibacterium jensenii (P. technicum). The propionic cocci and bacteria are related in the structure of their genomes, particularly, in the case of the bacterium P. jensenii (P. raffinosaceum)--49%. On the basis of studying the phenotypic characteristics, the fatty acid composition, the nucleotide composition of DNA, and the high degree of homology between the DNAs of the cocci and the bacterial species P. jensenii (P. raffinosaceum), the authors propose to assign the cocci to the genus Propionibacterium as a new species Propionibacterium coccoides.