[Ischemic stroke at a young age on the context of chronic myeloleukosis]. / Ishemicheskii insul't v molodom vozraste na fone khronicheskogo mieloleikoza.

The article describes the clinical search for diagnosis and treatment of a patient who developed a severe ischemic stroke at a young age, when specifying the cause of which chronic myeloleucosis was identified. The unavailability of patient compliance and non-compliance with the recommended examination at the outpatient stage led to the development of severe complications. It would seem that the diagnosis of chronic myeloid leukemia, which does not represent excessive complexity, with the development of an acute condition in a young patient, such as an ischemic stroke, results in a complex diagnostic search, complicated by developing comorbidities due to general decompensation of the body.

[An analysis of postoperative cognitive dysfunction in different methods of coronary artery bypass]. / Analiz posleoperatsionnoi kognitivnoi disfunktsii pri razlichnykh metodakh operatsii aortokoronarnogo shuntirovaniia.

AIM: To evaluate changes in cognitive functions in patients with coronary heart disease before and after coronary artery bypass grafting (CABG) in a planned manner. MATERIAL AND METHODS: The study included 192 patients divided into 3 groups: in group 1 patients (n=88) underwent standard CABG; in group 2 (n=61) different methods of CABG were used; a control group consisted of 43 people. MMSE, FAB, Clock drawing test, Shultz tables, semantic verbal fluency, Wechsler adult intelligence scale were used for neurological testing. RESULTS AND CONCLUSION: Postoperative cognitive dysfunction develops 3.2 times more often in patients after standard CABG. Patients in the group with a differentiated approach show a trend towards the improvement of cognitive functions after surgery.

[The application of the Multi-Touch pad for the evaluation of the fine motor activity of the wrist]. / Otsenka tonkoi motoriki kisti s ispol'zovaniem sensornoi paneli mul'ti-tach.

AIM: The objective of the present study was to elaborate the method for the evaluation of the fine motor activity of the wrist in the patients presenting with wrist movement disorders resulting from central hemiparesis and to demonstratee the reliability of such method through the calculation of the standard error of measurements and minimal the detectable change (MDC95%). MATERIAL AND METHODS: The study population was comprised of 42 patients who had undergone ischaemic stroke and suffered from the impairment of the upper limb functions . The deficit of the fine motor skills was estimated with the use of the original multi-touch diagnostic technique. The results of the assessment were compared with those of the measurement of upper limb motor activity based on the validated scales, such as the Fugl-Meyer Assessment (FMA) scale and the Nine Hole Peg Test (PHT). RESULTS: The study with the application of the multi-touch method for diagnostics of the fine motor skills has demonstrated the high internal consistency of the measurements, with the Cronbach's Alpha Reliability Coefficient amounting to 0.98. The re-test reliability was high, with the ICC=0.98 (95% CI 0.97-0.99). The Spearman rank-order correlation with the locomotion scale estimates gave evidence of the good associative links, with the Fugl-Meyer Assessment scale correlation coefficient making 0.55-0.66 and the Nine Hole Peg Test findings being -0.7. The Minimal Detectable Change (MDC95%) for the multi-touch method was found to be 12.67%. CONCLUSION: The objective diagnostics of the fine motor skill disturbances with the use of the original multi-touch method has demonstrated its high reliability and a high degree of correlation with the estimates obtained with the application of the modern validated scales in the patients who had undergone ischaemic stroke. Therefore, this method can be recommended for clinical use.