ABSTRACT
TITLE: Paralisis aislada de la mano debido a un infarto isquemico.
Subject(s)
Brain Ischemia/complications , Frontal Lobe/physiopathology , Hand , Paralysis/etiology , Aged , Brain Ischemia/diagnostic imaging , Diagnosis, Differential , Dyslipidemias/epidemiology , Female , Frontal Lobe/diagnostic imaging , Functional Laterality , Hand Strength , Humans , Hypertension/epidemiology , Intracranial Arteriosclerosis/complications , Ischemic Attack, Transient/complications , Magnetic Resonance Imaging , Male , Middle Aged , Neuroimaging , Paralysis/epidemiology , Paralysis/physiopathology , Prospective Studies , Risk FactorsABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Cerebral Infarction/complications , Hand/physiopathology , Paralysis/etiology , Magnetic Resonance Imaging , Cerebral Infarction/diagnostic imagingABSTRACT
BACKGROUND: Autism Spectrum Disorders (ASD) and psychosis share deficits in social cognition. The insular region has been associated with awareness of self and reality, which may be basic for proper social interactions. METHODS: Total and regional insular volume and thickness measurements were obtained from a sample of 30 children and adolescents with ASD, 29 with early onset first-episode psychosis (FEP), and 26 healthy controls (HC). Total, regional, and voxel-level volume and thickness measurements were compared between groups (with correction for multiple comparisons), and the relationship between these measurements and symptom severity was explored. RESULTS: Compared with HC, a shared volume deficit was observed for the right (but not the left) anterior insula (ASD: p = 0.007, FEP: p = 0.032), and for the bilateral posterior insula: (left, ASD: p = 0.011, FEP: p = 0.033; right, ASD: p = 0.004, FEP: p = 0.028). A voxel-based morphometry (VBM) conjunction analysis showed that ASD and FEP patients shared a gray matter volume and thickness deficit in the left posterior insula. Within patients, right anterior (r = -0.28, p = 0.041) and left posterior (r = -0.29, p = 0.030) insular volumes negatively correlated with the severity of insight deficits, and left posterior insular volume negatively correlated with the severity of 'autistic-like' symptoms (r = -0.30, p = 0.028). CONCLUSIONS: The shared reduced volume and thickness in the anterior and posterior regions of the insula in ASD and FEP provides the first tentative evidence that these conditions share structural pathology that may be linked to shared symptomatology.
Subject(s)
Autism Spectrum Disorder/pathology , Cerebral Cortex/pathology , Magnetic Resonance Imaging/methods , Psychotic Disorders/pathology , Adolescent , Autism Spectrum Disorder/diagnostic imaging , Cerebral Cortex/diagnostic imaging , Child , Female , Humans , Male , Psychotic Disorders/diagnostic imagingABSTRACT
OBJECTIVE: To prenatally identify pregnant women at risk of developing congenital infection due to human cytomegalovirus (HCMV). METHODS: One thousand one hundred and thirty-one pregnant women from three municipalities from Havana City were serologically screened for HCMV infection (IgM/IgG, IgG avidity) from January 2007 to January 2008. Demographical, epidemiological, and clinical variables were correlated to serologic status to identify predictors of seroconversion in pregnancy. RESULTS: The majority of women were seropositive to HCMV (92.6%); 27 women (2.4%) developed HCMV active infection during pregnancy, defined by the detection of IgG+ and IgM+ (7 women), IgM+ and IgG- (2 women), and IgG seroconversion (18 women). Susceptibility of active HCMV infection during pregnancy was associated with maternal age < 20 years and nulligravidity. Primary infection was detected in 20 pregnant women (1.8%), whereas 7 patients (0.6%) had active non-primary infection. CONCLUSION: Although pregnant women in Cuba have high seroprevalence rates for HCMV, those younger than 20 years and nulligravidae are at risk of acquiring infection during pregnancy.
Subject(s)
Cytomegalovirus Infections/epidemiology , Pregnancy Complications, Infectious/epidemiology , Adult , Age Distribution , Cuba/epidemiology , Female , Follow-Up Studies , Humans , Pregnancy , Seroepidemiologic Studies , Young AdultABSTRACT
No disponible
