Correlation between cytogenetic abnormalities in cells and metabolic shifts in children with spinal deformities.

We studied the relationship between cytogenetic abnormalities in buccal epithelial cells and metabolic shifts in children with scoliosis and kyphosis. The incidence of nucleus abnormalities and the corresponding metabolic shifts were found to depend on the presence of spinal deformities and ecological factors. The problem of formation of risk groups for spinal deformities in ecologically unfavorable regions is discussed.