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2.
Radiats Biol Radioecol ; 37(3): 336-42, 1997.
Article in Russian | MEDLINE | ID: mdl-9244520

ABSTRACT

A comparison between biological effects of electron radiation (25 and 50 MeV) at doses of 100-300 Gy and with pulse recurrence frequencies from 3 to 2400 s-1, using general damage severity, distinctiveness of separate clinical manifestations and incidence of extremely severe forms of radiation sickness as criteria, has demonstrated some peculiarities of radiation pathology in rats under these circumstances. The pulse recurrence frequency influence varies with the criterion applied.


Subject(s)
Electrons/adverse effects , Radiation Injuries, Experimental/etiology , Animals , Brain Diseases/etiology , Dose-Response Relationship, Radiation , Intestinal Diseases/etiology , Male , Rats
3.
Radiobiologiia ; 30(5): 639-42, 1990.
Article in Russian | MEDLINE | ID: mdl-2251353

ABSTRACT

Certain peculiarities have been revealed in the development of radiation sickness in guinea pigs subjected to nonuniform irradiation with superlethal doses. With electron and gamma-neutron radiation LD50/1.5 was 116.11 and 114.48 Gy respectively, when delivered to whole body, and 133.40 and 111.72 Gy when delivered to the posterior part of the body.


Subject(s)
Radiation Injuries, Experimental/pathology , Animals , Electrons , Guinea Pigs , Lethal Dose 50 , Male , Neutrons , Radiation Dosage , Radiation Injuries, Experimental/mortality
4.
Radiobiologiia ; 29(4): 571-3, 1989.
Article in Russian | MEDLINE | ID: mdl-2780995

ABSTRACT

The RBE coefficient of neutrons (0.85 MeV) was 1.87 in comparison with that of electron radiation (8 MeV) as determined by the death rate of guinea pigs with the cerebral form of radiation sickness. LD50/1.5 amounted to 43.2 and 80.7 Gy. The dynamics of clinical symptoms at the height of the disease is discussed.


Subject(s)
Brain Diseases/etiology , Fast Neutrons , Neutrons , Radiation Injuries, Experimental/etiology , Animals , Brain Diseases/mortality , Electrons , Fast Neutrons/adverse effects , Gamma Rays , Guinea Pigs , Lethal Dose 50 , Male , Neutrons/adverse effects , Radiation Injuries, Experimental/mortality , Relative Biological Effectiveness
5.
Radiobiologiia ; 29(2): 164-7, 1989.
Article in Russian | MEDLINE | ID: mdl-2717708

ABSTRACT

Relative biological effectiveness (RBE) coefficient of 0.85 MeV neutrons was 1.87 in comparison with 0.66 MeV gamma radiation (137Cs) when estimated by the death rate of guinea pigs with intestinal form of radiation sickness. LD50/5 was 5.9 and 11.06 respectively. Features of the mortality rate dynamics, clinical picture and pathoanatomical changes are discussed.


Subject(s)
Intestinal Diseases/etiology , Neutrons , Radiation Injuries, Experimental/etiology , Animals , Gamma Rays , Guinea Pigs , Intestinal Diseases/mortality , Intestinal Diseases/pathology , Male , Radiation Injuries, Experimental/mortality , Radiation Injuries, Experimental/pathology , Relative Biological Effectiveness , Time Factors
6.
Radiobiologiia ; 27(3): 417-9, 1987.
Article in Russian | MEDLINE | ID: mdl-3615827

ABSTRACT

A comparative study was made of the death rate of guinea pigs after neutron (0.85 MeV) and 137Cs-gamma-radiation (0.66 MeV); LD50/30 were 1.58 and 3.44 Gy respectively. CRBE of neutrons was 2.2 as determined by median lethal dose values for guinea pigs.


Subject(s)
Longevity/radiation effects , Neutrons , Animals , Gamma Rays , Guinea Pigs , Lethal Dose 50 , Male , Relative Biological Effectiveness , Time Factors
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