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1.
Am J Emerg Med ; 35(11): 1787.e5-1787.e6, 2017 Nov.
Article in English | MEDLINE | ID: mdl-28801039

ABSTRACT

Kohler's disease is rare cause of foot pain and limping in the pediatric population. The exact etiology of Kohler's disease is unknown. It usually presents as sudden and unexplained foot pain and limping. We report a case of a 5-year-old male who presented to the Pediatric Emergency Department with foot pain and inability to bear weight for two days after overactivity and acute foot injury. The patient was eventually diagnosed with Kohler's disease (avascular necrosis of the navicular bone). Although Kohler's disease is not very common, it should be considered in the differential diagnosis of foot pain in the pediatric population, as it may prevent unnecessary tests and treatments.


Subject(s)
Osteochondrosis/diagnostic imaging , Osteonecrosis/diagnostic imaging , Tarsal Bones/diagnostic imaging , Child, Preschool , Diagnosis, Differential , Foot Injuries/diagnosis , Humans , Male
2.
Am J Case Rep ; 16: 146-8, 2015 Mar 10.
Article in English | MEDLINE | ID: mdl-25754813

ABSTRACT

BACKGROUND: When discussing known poisons and their clinical consequences, few physicians are aware of the deadly poison abrin. The common symptoms of abrin toxicity include nausea, vomiting, abdominal pain, and diarrhea with or without bloody stool. However, with an estimated fatal human dose of less than 1 microgram/kg, death due to complications such as liver failure, renal failure, and cerebral edema are possible. CASE REPORT: An 18-month-old male presented to the emergency department with an abrupt onset of fever, vomiting, diarrhea, and dehydration. The parents had assumed the child was suffering from a severe gastroenteritis until they noticed 3 consecutive diapers containing colorful seeds that were identified by poison control as belonging to the Abrus precatorius plant. The child's gastrointestinal symptoms were consistent with reported cases of abrin poisoning, but the patient also had an isolated and significantly elevated alkaline phosphatase, with testing unable to reveal the responsible pathological process. CONCLUSIONS: To reduce morbidity and possible mortality, parents and pediatricians alike should be conscious of the danger the Abrus precatorius seed poses to the pediatric population. Children are at a greater risk of ingesting these seeds due to their colorful appearance, and the consequences could be fatal. Through this case report we hope to raise public awareness regarding this toxin. This includes the management of known cases, as well as the possibility of encountering an isolated elevated alkaline phosphatase level as a laboratory finding if ingestion occurs.


Subject(s)
Abrin/poisoning , Abrus/poisoning , Plant Poisoning/diagnosis , Seeds/poisoning , Diarrhea/chemically induced , Humans , Infant , Male , Plant Poisoning/complications , Plant Poisoning/therapy , Vomiting/chemically induced
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