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Introduction: In diabetes mellitus (DM) patients, obtaining a good night's sleep is crucial for maintaining body caloric intake, controlling insulin levels, and reducing the likelihood of engaging in unhealthy behavior. Patients with poor sleep quality may experience impaired glycemia, playing a significant role in the development of chronic complications. This study aims to explore the effects of DM complications on sleep quality among Saudi Arabian patients. Patient and Methods: This is a cross-sectional study conducted among patients with diabetes. A self-administered, validated questionnaire translated into Arabic was distributed among diabetic patients using an online survey. The questionnaire includes sociodemographic characteristics (i.e. age, gender, marital status, etc.), the medical history of the patients, and a questionnaire about sleep quality. Results: Out of 4171 patients involved, 52.7% were females and 27.7% were aged between 40 and 60 years old. The prevalence of patients with perceived poor sleep quality was 24.1%. Significant predictors of poor sleep quality were the gender female, having social stressors, comorbid sleep disorders, associated comorbidities, increasing HbA1c levels, being overweight/obese, and diabetes complications. Furthermore, sleep disturbance, taking sleep medications, daytime sleepiness, and having bad dreams during sleep were also identified as prognostic factors for poor sleep quality. Conclusion: The subjective poor sleep quality of patients with diabetes was 24.1%. Poor sleep quality was significantly demonstrated by females who were having social stressors, comorbid sleep disorders, comorbidities, uncontrolled HbA1c levels, elevated BMI levels, and complications of diabetes. However, regular physical activity and adequate sleep were estimated to be the protective factors against poor sleep quality. Further research is needed to establish the effect of sleep quality among patients with DM.
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[This corrects the article DOI: 10.5334/aogh.2912.].
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This paper provides a rudimentary insight into the influence of heat transfer on the transport characteristics of a second-grade dusty fluid flown in a flexible tube with walls subjected to the peristaltic motion. Both dust particles and fluid movements were modeled using the coupled differential equations. The effects of different types of parameters such as Reynolds number, Prandtl number, Grashof number, wave number, wave amplitude ratio, second grade parameter as well as nature of the heat source and sink are studies on the dust particles velocity, fluid velocity, temperature, pressure profiles of the fluid and streamline patterns of the fluid. The derived equations were solved analytically via the standard perturbation method to determine the fluid temperature, streamline pattern and velocity of the dust particles as well as fluid. The values in the increase of pressure and frictional forces were calculated numerically using DSolve of the Mathematica 11 software ( https://www.wolfram.com/mathematica/new-in-11/ ). In addition, the trapping mechanisms were ascertained by computing the streamlines and various physical parameters. The obtained results were validated with the state-of-the-art literature reports. It was claimed that our systematic approach may constitute a basis for accurately examining the impact of heat transfer on the peristaltic transport of a complex fluid through narrow tubes, useful for diverse medical applications such as the gastric fluid flow through the small intestine during endoscopy. Numerical results are computed and discussed numerically and presented through graphs. The impacts of pertinent parameters on the aforementioned quantities are examined by plotting graphs on the basis of computational results. The results indicate that the effect of parameters is very pronounced. A suitable comparison has been made with the prior results in the literature as a limiting case of the considered problem.
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Stem cells play a critical role in regulatory operations, overseeing tissue regeneration and tissue homeostasis. In this paper, a mathematical model is proposed and analyzed to study the impact of stem cell transplantation on the dynamical behavior of stroke therapy, which is assumed to be based on transplanting dead brain cells following a stroke. We transform the method of using hierarchical cell systems into a method of using different compartment variables by using ordinary differential equations, each of which elucidates a well-defined differentiation stage along with the effect of mature cells in improving the brain function after a stroke. Stem cells, progenitor cells, and the impacts of the stem cells transplanted on brain cells are among the variables considered. The model is studied analytically and solved numerically using the fourth-order Runge-Kutta method. We analyze the structure of equilibria, the ability of neural stem cells to proliferate and differentiate, and the stability properties of equilibria for stem cell transplantation. The model is considered to be stable after transplantation if the stem cells and progenitor cells differentiate into mature nerve cells in the brain. The results of the model analysis and simulation facilitate the identification of various biologically probable parameter sets that can explain the optimal time for stem cell replacement of damaged brain cells. Associating the classified parameter sets with recent experimental and clinical findings contributes to a better understanding of therapeutic mechanisms that promote the reconstitution of brain cells after an ischemic stroke.
Subject(s)
Neural Stem Cells , Stroke , Brain , Cell Differentiation , Cell Proliferation , Humans , Stroke/therapyABSTRACT
Background: Waterpipe smoking (WPS), also called shisha, has considerable short and long-term effects on human health. WPS has become increasingly popular among the youth in Jazan society. Hence, this study is aimed to assess the prevalence, predictors, and characteristics (knowledge and attitude) of WPS among male and female students at Jazan University. Methods and materials: A descriptive, cross-sectional study was conducted among 405 students. Data were collected using a self-administered validated questionnaire. The prevalence and predictors of WPS and the association between important socio-demographic factors (sex, type of college, parents smoking, home mate smoking and close friend smoking) were studied. Results: The prevalence of WPS among students was high, approximately 34.0%. The prevalence rate was significantly higher in males (42.5%, n = 74) than in females (27.0%, n = 57) (p = 0.001). The main predictors of WPS were: being male (OR = 1.99, 95% CI [1.30, 3.06], p = 0.001), believing that shisha smoking is less harmful & addictive than cigarettes (OR = 3.84, 95% CI [1.88, 7.83], p < 0.001 and 3.80, 95% CI [2.0, 7.11], p < 0.001, respectively), and having a close friend who smokes (OR = 6.85, 95% CI [3.84, 12.22], p < 0.001). Conclusions: WPS prevalence among Jazan University students was high, and the most influential factors were being male, having smoker housemates and friends, and having incorrect thoughts and beliefs.
