An improved breast cancer classification with hybrid chaotic sand cat and Remora Optimization feature selection algorithm.

Breast cancer is one of the most often diagnosed cancers in women, and identifying breast cancer histological images is an essential challenge in automated pathology analysis. According to research, the global BrC is around 12% of all cancer cases. Furthermore, around 25% of women suffer from BrC. Consequently, the prediction of BrC depends critically on the quick and precise processing of imaging data. The primary reason deep learning models are used in breast cancer detection is that they can produce findings more quickly and accurately than current machine learning-based techniques. Using a BreakHis dataset, we demonstrated in this work the viability of automatically identifying and classifying BrC. The first stage is pre-processing, which employs an Adaptive Switching Modified Decision Based Unsymmetrical Trimmed Median Filter (ASMDBUTMF) to remove high-density noise. After the image has been pre-processed, it is segmented using the Thresholding Level set approach. Next, we propose a hybrid chaotic sand cat optimization technique, together with the Remora Optimization Algorithm (ROA) for feature selection. The suggested strategy facilitates the acquisition of precise functionality attributes, hence simplifying the detection procedure. Additionally, it aids in resolving problems pertaining to global optimization. Following the selection, the best characteristics proceed to the categorization procedure. A DL classifier called the Conditional Variation Autoencoder is used to discriminate between cancerous and benign tumors while categorizing them. Consequently, a classification accuracy of 99.4%, Precision of 99.2%, Recall of 99.1%, F- score of 99%, Specificity of 99.14%, FDR of 0.54, FNR of 0.001, FPR of 0.002, MCC of 0.98 and NPV of 0.99 were obtained using the proposed approach. Furthermore, compared to other research using the current BreakHis dataset, the results of our research are more desirable.

Identification and Localization of Indolent and Aggressive Prostate Cancers Using Multilevel Bi-LSTM.

Identifying indolent and aggressive prostate cancers is a critical problem for optimal treatment. The existing approaches of prostate cancer detection are facing challenges as the techniques rely on ground truth labels with limited accuracy, and histological similarity, and do not consider the disease pathology characteristics, and indefinite differences in appearance between the cancerous and healthy tissue lead to many false positive and false negative interpretations. Hence, this research introduces a comprehensive framework designed to achieve accurate identification and localization of prostate cancers, irrespective of their aggressiveness. This is accomplished through the utilization of a sophisticated multilevel bidirectional long short-term memory (Bi-LSTM) model. The pre-processed images are subjected to multilevel feature map-based U-Net segmentation, bolstered by ResNet-101 and a channel-based attention module that improves the performance. Subsequently, segmented images undergo feature extraction, encompassing various feature types, including statistical features, a global hybrid-based feature map, and a ResNet-101 feature map that enhances the detection accuracy. The extracted features are fed to the multilevel Bi-LSTM model, further optimized through channel and spatial attention mechanisms that offer the effective localization and recognition of complex structures of cancer. Further, the framework represents a promising approach for enhancing the diagnosis and localization of prostate cancers, encompassing both indolent and aggressive cases. Rigorous testing on a distinct dataset demonstrates the model's effectiveness, with performance evaluated through key metrics which are reported as 96.72%, 96.17%, and 96.17% for accuracy, sensitivity, and specificity respectively utilizing the dataset 1. For dataset 2, the model achieves the accuracy, sensitivity, and specificity values of 94.41%, 93.10%, and 94.96% respectively. These results surpass the efficiency of alternative methods.