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1.
Heliyon ; 9(7): e17957, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37483827

ABSTRACT

Over the last decade, pharmaceutical businesses have battled to standardize product traceability across the supply chain process, enabling counterfeiters to enter the market with counterfeit pharmaceuticals. As a result, an end-to-end product tracking system is crucial for ensuring product safety and eliminating counterfeit products across the pharmaceutical supply chain. In this paper, we introduce PharmaChain, a decentralized hyperledger fabric framework that leverages confidentiality, accountability, and interoperability. This system enables on-chain and off-chain storage for secured, rapid transactions, along with smart contracts establishing data provenance. To demonstrate security, we have provided double signing through the elliptic curve digital signature algorithm, hash data encryption, and 33% node attack. The purpose of this suggested framework is to engage particular governance disciplines to assess its effectiveness in improving drug traceability across the pharmaceutical supply chain to preserve public health by preventing counterfeit pharmaceuticals.

2.
Heliyon ; 8(10): e11052, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36254291

ABSTRACT

Question answering (QA) system in any language is an assortment of mechanisms for obtaining answers to user questions with various data compositions. Reading comprehension (RC) is one type of composition, and the popularity of this type is increasing day by day in Natural Language Processing (NLP) research area. Some works have been done in several languages, mainly in English. In the Bangla language, neither any dataset available for RC nor any work has been done in the past. In this research work, we develop a question-answering system from RC. For doing this, we construct a dataset containing 3636 reading comprehensions along with questions and answers. We apply a transformer-based deep neural network model to obtain convenient answers to questions based on reading comprehensions precisely and swiftly. We exploit some deep neural network architectures such as LSTM (Long Short-Term Memory), Bi-LSTM (Bidirectional LSTM) with attention, RNN (Recurrent Neural Network), ELECTRA, and BERT (Bidirectional Encoder Representations from Transformers) to our dataset for training. The transformer-based pre-training language architectures BERT and ELECTRA perform more prominently than others from those architectures. Finally, the trained model of BERT performs a satisfactory outcome with 87.78% of testing accuracy and 99% training accuracy, and ELECTRA provides training and testing accuracy of 82.5% and 93%, respectively.

3.
J Med Syst ; 35(3): 353-67, 2011 Jun.
Article in English | MEDLINE | ID: mdl-20703554

ABSTRACT

Cancer is increasing the total number of unexpected deaths around the world. Until now, cancer research could not significantly contribute to a proper solution for the cancer patient, and as a result, the high death rate is uncontrolled. The present research aim is to extract the significant prevention factors for particular types of cancer. To find out the prevention factors, we first constructed a prevention factor data set with an extensive literature review on bladder, breast, cervical, lung, prostate and skin cancer. We subsequently employed three association rule mining algorithms, Apriori, Predictive apriori and Tertius algorithms in order to discover most of the significant prevention factors against these specific types of cancer. Experimental results illustrate that Apriori is the most useful association rule-mining algorithm to be used in the discovery of prevention factors.


Subject(s)
Health Behavior , Neoplasms/prevention & control , Neoplasms/psychology , Risk Assessment/methods , Algorithms , Databases, Factual , Humans , Neoplasms/epidemiology , Neoplasms/physiopathology , Risk Factors
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