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1.
Healthcare (Basel) ; 12(2)2024 Jan 09.
Article in English | MEDLINE | ID: mdl-38255042

ABSTRACT

Lifestyle behaviors are daily habits influenced by social and environmental factors. This study examined lifestyle behaviors and their associations with sociodemographics, comorbidities, and pain in Saudi university students during the academic year 2021 and 2022. All students received the study invitation via university emails to complete an online questionnaire. The questionnaire included four sections (sociodemographics, health-related information, desired health promotion activities, and a lifestyle behavior assessment) via Health-Promoting Lifestyle Profile II (HPLP-II). The associations between study variables were assessed using Pearson's correlation and multiple linear regression. The study questionnaire was completed by 1112 students. No correlation was found between sociodemographics and lifestyle-behavior-related factors except for students in the College of Science who appeared to have good lifestyle behaviors (an increase in HPLP II total scores of 3.69). Students with mental health issues have poorer lifestyle behaviors and spend more time sitting (p < 0.00). Students without disabilities have lower scores in health responsibility, physical activity, nutrition, and stress management, while auditory disability specifically lowers health responsibility (p < 0.00). Pain was not associated with any assessed lifestyle behaviors. This study identified several significant correlations and differences between variables such as age, sedentary behavior, sleep duration, disability status, college major, and lifestyle behaviors among PNU students. These findings provide insights into the factors that influence students' health-promoting behaviors and can help guide interventions for promoting healthier lifestyles on campus. Targeted health promotion strategies at an early age could help in decreasing overall noncommunicable disease incidents later in life. The study results should be interpreted taking into consideration that the collected data were cross-sectional and self-reported. In conclusion, the findings of this study clearly demonstrate the need for specific lifestyle and health-promoting programs that are directed toward university students.

2.
Appl Opt ; 62(23): 6163-6168, 2023 Aug 10.
Article in English | MEDLINE | ID: mdl-37707084

ABSTRACT

The optical multiplexer was created at a nanoscale plasmonic structure utilizing the finite element method (FEM) with COMSOL version 5.5 software to enable maximum light confinement, high-speed optical systems, and a tiny structure. The metal-insulator-metal technology at a nanoscale dimension is used for creating the 4×1 multiplexer. In this design, the transmission threshold (T t h r e s h o l d ) is selected to be 100% for separating between logic "1" and logic "0" at a 1310 nm operating wavelength. The modulation depth (MD), contrast ratio (CR), and insertion loss (IL) characteristics were explained to evaluate the performance of the multiplexer. The CR has 3.48 dB, the MD offers an ideal performance with 95.28 %, and the IL has 3.31 dB.

3.
J Med Life ; 16(12): 1756-1759, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38585532

ABSTRACT

Fatty acids, particularly omega-3, omega-6, and omega-9, play a vital role in various biological processes. As the body cannot synthesize omega-3 and omega-6, dietary sources of these fatty acids are essential. Each omega fatty acid has a distinct chemical structure, source, and function. Cisplatin (CP) treatment is known to cause acute kidney injury (AKI) due to its inflammatory effects. This study explored the renoprotective potential of omega-3-6-9 when co-administered with cisplatin in a mice model. We divided adult mice into five groups: a control group received 0.5 ml of liquid paraffin; a cisplatin-only group; two groups were treated with low (50 mg/kg) and high (100 mg/kg) doses of omega-3-6-9 plus cisplatin; and a final group received vitamin E before cisplatin administration. The administration of omega-3-6-9 significantly decreased pro-inflammatory modulators and kidney function markers such as TNF-α, IL-1ß, blood urea nitrogen, and creatinine, indicating potential renoprotective effects. Our research concluded that omega-3- 6- 9 had anti-inflammatory properties and was effective against the harmful effects of cisplatin.


Subject(s)
Acute Kidney Injury , Cisplatin , Mice , Animals , Cisplatin/pharmacology , Kidney , Acute Kidney Injury/chemically induced , Acute Kidney Injury/prevention & control , Acute Kidney Injury/drug therapy , Anti-Inflammatory Agents/pharmacology , Fatty Acids/adverse effects
4.
Article in English | MEDLINE | ID: mdl-36554560

ABSTRACT

During the COVID-19 pandemic, telemedicine was broadly adopted for patient care. Considering this experience, it is crucial to understand the perceptions of teleclinic healthcare professionals. In Saudi Arabia, telemedicine literature was restricted to physicians working in government and private hospitals. This study examined perceptions in relation to telemedicine among physicians and other healthcare professionals practicing in Saudi Arabian military hospitals in the Taif region. During COVID-19, telemedicine was implemented in military hospitals; consequently, this study assists in evaluating introduced practices and the perceptions of health professionals regarding these new practices. A quantitative, descriptive, correlational, and cross-sectional study was undertaken on healthcare professionals (N = 153). Twenty (20) items based on standardized measures were used to collect data using an online questionnaire. The measures contained three subscales: perceived usefulness, perceived ease, and behavioral intention. It was hypothesized that the perception of teleclinic usefulness and ease score by healthcare providers would be significantly correlated with behavioral intention. Descriptive statistics for mean, frequency, and standard deviation, as well as a Pearson correlation coefficient and regression analysis, were conducted to assess the relationship and predictive association between variables. In addition, a focus group discussion was organized to collect information directly from healthcare professionals. Most of the participants were approximately 40 years of age, Saudi Nationals (63%), medical specialists (62%), and were involved in teleclinic practices before the COVID-19 pandemic (60%). The reliability of all three scales was determined to be acceptable (α = 0.75-0.91). Perceived usefulness and perceived ease were shown to be significantly correlated with behavioral intention (r = 0.877, p = 0.05). In addition, the regression analysis indicated that perceived usefulness and perceived ease are predictors of the behavioral intention (R2 = 0.777, F (2,152) = 261.76, p = 0.001) of teleclinic practices among healthcare professionals. The positive perception of telemedicine integration in healthcare systems revealed by this study is a major catalyst for continuous adoption. On the other hand, certified telemedicine platforms, on-the-job training, Internet of things, and a flexible approach are required to find opportunities and enhancements in telemedicine interactions.


Subject(s)
COVID-19 , Delivery of Health Care, Integrated , Telemedicine , Humans , COVID-19/epidemiology , Saudi Arabia/epidemiology , Cross-Sectional Studies , Pandemics , Reproducibility of Results , Health Personnel , Surveys and Questionnaires , Perception
5.
Wiad Lek ; 75(5 pt 2): 1305-1308, 2022.
Article in English | MEDLINE | ID: mdl-35758448

ABSTRACT

OBJECTIVE: The aim: To assess nurses' infection control knowledge at basic health care clinics and knowledge in practices nurses on infection control. PATIENTS AND METHODS: Materials and methods: This is cross-sectional study, conducted in primary health care centers within descriptive research in Al-Hilla City, from 17th May, 2021 to 2nd October, 2021. The researcher created the instruments to achieve the study's objectives through non-probability sampling: the purposive sample is made from of 140 searched, who worked in the dressing and immunization units of primary health care centers were chosen, and two study instruments [questionnaire and demographic data] were used for proper data collection. RESULTS: Results: In this study revealed that (47.1%) at age groups (35-39) ages, the current study's findings revealed that (69.8%) of Males made up the sample and (60.7%) graduated from a nursing school (50%) have Training courses and (42.1%) consume (16-20) years of experience. And The nurses' general knowledge levels about infection control were good. CONCLUSION: Conclusions: The majority of health-care personnel' knowledge, attitude, and practice regarding basic precautions were adequate, favorable, and safe by the expected standard.


Subject(s)
Attitude of Health Personnel , Health Knowledge, Attitudes, Practice , Adolescent , Adult , Clinical Competence , Cross-Sectional Studies , Female , Humans , Infection Control , Iraq , Male , Primary Health Care , Surveys and Questionnaires , Young Adult
7.
J Diabetes Investig ; 11(5): 1344-1351, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32017439

ABSTRACT

AIMS/INTRODUCTION: Vitamin D levels are negatively correlated with prediabetes risk and hemoglobin A1c levels in individuals with prediabetes. The data are, however, scarce and inconsistent among different populations. We aimed to assess the association of vitamin D with prediabetes risk and hemoglobin A1c levels in young Saudi women with normoglycemia and prediabetes. MATERIALS AND METHODS: We analyzed the data of individuals without diabetes (without diabetes history and hemoglobin A1c <6.4%) from the Princess Nourah bint Abdulrahman University's non-communicable diseases student registry. Demographic data, anthropometric and blood pressure measurements, and hemoglobin A1c and vitamin D results were retrieved and analyzed. RESULTS: In total, 345 participants were included in the analysis. The prediabetes status showed no association with vitamin D levels, but it was significantly associated with the participants' weight and body mass index. Additionally, there was no correlation between the levels of vitamin D and hemoglobin A1c across the whole population, even after correction for body mass index. However, in the body mass index subgroups, when individuals with potentially harmful levels of vitamin D (>125 nmol/L) were excluded, a positive association was detected between vitamin D and hemoglobin A1c levels in the underweight individuals. Hemoglobin A1c values showed a positive correlation only with bodyweight and body mass index. CONCLUSIONS: Vitamin D levels did not predict prediabetes status and showed no correlation with hemoglobin A1c levels in this population. Vitamin D levels' effect on the risk of prediabetes might be small compared with other well-established risk factors, such as obesity.


Subject(s)
Biomarkers/blood , Blood Glucose/analysis , Diabetes Mellitus, Type 2/epidemiology , Glycated Hemoglobin/analysis , Prediabetic State/epidemiology , Vitamin D/blood , Vitamins/blood , Adolescent , Adult , Body Mass Index , Case-Control Studies , Diabetes Mellitus, Type 2/blood , Diabetes Mellitus, Type 2/pathology , Female , Follow-Up Studies , Humans , Prediabetic State/blood , Prediabetic State/pathology , Prognosis , Risk Factors , Saudi Arabia/epidemiology , Young Adult
8.
Blood ; 134(17): 1373-1384, 2019 10 24.
Article in English | MEDLINE | ID: mdl-31434707

ABSTRACT

Transferrin, the major plasma iron-binding molecule, interacts with cell-surface receptors to deliver iron, modulates hepcidin expression, and regulates erythropoiesis. Transferrin binds and releases iron via either or both of 2 homologous lobes (N and C). To test the hypothesis that the specificity of iron occupancy in the N vs C lobe influences transferrin function, we generated mice with mutations to abrogate iron binding in either lobe (TfN-bl or TfC-bl). Mice homozygous for either mutation had hepatocellular iron loading and decreased liver hepcidin expression (relative to iron concentration), although to different magnitudes. Both mouse models demonstrated some aspects of iron-restricted erythropoiesis, including increased zinc protoporphyrin levels, decreased hemoglobin levels, and microcytosis. Moreover, the TfN-bl/N-bl mice demonstrated the anticipated effect of iron restriction on red cell production (ie, no increase in red blood cell [RBC] count despite elevated erythropoietin levels), along with a poor response to exogenous erythropoietin. In contrast, the TfC-bl/C-bl mice had elevated RBC counts and an exaggerated response to exogenous erythropoietin sufficient to ameliorate the anemia. Observations in heterozygous mice further support a role for relative N vs C lobe iron occupancy in transferrin-mediated regulation of iron homeostasis and erythropoiesis.


Subject(s)
Erythropoiesis , Iron/metabolism , Transferrin/metabolism , Animals , Binding Sites , Erythrocyte Count , Erythropoietin/metabolism , Female , Homeostasis , Male , Mice , Mice, Transgenic , Mutagenesis, Site-Directed , Proto-Oncogene Proteins c-akt/metabolism , Transferrin/chemistry , Transferrin/genetics
9.
Rev Sci Instrum ; 81(7): 074901, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20687751

ABSTRACT

This article reports on the effect of aluminum (Al) volume fraction concentration on the thermal conductivity and thermal diffusivity of Al nanoparticles suspended in water, ethylene glycol, and ethanol based fluids prepared by the one step method. The Al nanoparticles were independently produced and then mixed with a base fluid to produce the nanoparticles suspension. The thermal conductivity and thermal diffusivity of the nanofluids were measured using the hot wire-laser beam displacement technique. The thermal conductivity and thermal diffusivity were obtained by fitting the experimental data to the numerical data simulated for Al in distilled water, ethylene glycol, and ethanol. The thermal conductivity and thermal diffusivity of the nanofluids increase with an increase in the volume fraction concentration.

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