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J Reprod Med ; 48(3): 201-3, 2003 Mar.
Article in English | MEDLINE | ID: mdl-12698780

ABSTRACT

BACKGROUND: Induction of ovulation in the course of infertility treatment is increasingly commonplace in the 21st century. As a consequence, it can be expected that previously unrecognized complications of the procedure will be reported. CASE: A 36-year-old woman presented with severe pelvic pain and hyponatremia after ovarian stimulation with gonadotropins. After admission with a presumptive diagnosis of ovarian hyperstimulation syndrome, a further family history revealed acute intermittent porphyria. A 24-hour urine collection confirmed the diagnosis. CONCLUSION: Hormonal therapy for induction of ovulation in the course of infertility treatment may precipitate attacks of acute intermittent porphyria. A careful history must be undertaken prior to administration of such hormonal preparations.


Subject(s)
Follicle Stimulating Hormone/adverse effects , Hormones/adverse effects , Ovulation Induction/adverse effects , Porphyria, Acute Intermittent/chemically induced , Adult , Female , Humans , Porphyria, Acute Intermittent/diagnosis , Porphyria, Acute Intermittent/therapy , Pregnancy
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