ABSTRACT
Background: In orthodontic procedures, mini-implants are routinely used as temporary anchorage devices. Early failure is primarily attributed to a variety of issues, which are mostly connected to the quality and geometry of the screw that lead to insufficient primary stability. Objectives: To evaluate the primary stability of different sizes and brands of orthodontic mini-implants by optimizing the insertion torque value (ITV) and to clear out which one has the greatest primary stability among the most widely used mini-implants by orthodontists. Methods: Eighty-two self-drilling mini-implants from three different brands with different sizes were used (Optimus Ortho System (Osteonic made in Korea), Smart anchor (GNI made in Korea) (1.4 × 6, 1.6 × 8 and 1.8 × 10mm) and Morelli (made in Brazil) (1.5 × 6, 1.5 × 8 and 1.5 × 10mm), made from (Ti 6Al 4V). All were drilled at a 60° angle on Sixty artificial bone blocks made from polyurethane foam with a digital torque meter device (Orthonia, Jeil made in Korea), pullout strength (tensile force) was measured with a universal testing machine to find out the best brand and size in the mean of primary stability. Data were analyzed using SPSS Version 25 and JMP Pro Version 16 software using the One-way ANOVA test, the Post hoc and Tukey HCD tests. Results: There were significant differences between the pullout strength of different sizes for the GNI and OSTEONIC brands, while for the MORELLI brand there were no significant differences between the three different sizes considering ITV (10Ncm) whereas for ITV (20Ncm) there was a significant difference between the different sizes for the pullout of all three brands. GNI was the best brand for all the selected sizes with ITV (10Ncm) and size 1.4 × 6 for ITV (20Ncm), whereas OSTEONIC sizes 1.6 × 8 and 1.8 × 10 were the best for ITV (20Ncm) in term of primary stability. Conclusion: GNI screws were demonstrated higher primary among the three widely used brands followed by OSTEONIC for size 1.6 × 8 and 1.8 × 10 while MORELLI was the least resistant to dislodgement for the two torque insertion values 10 N/cm and 20 N/cm.
ABSTRACT
OBJECTIVES: The present study aims to reveal the systemic effects of submucosal injection of plasma-rich platelets (PRP) on blood inflammatory markers which was used in an attempt to reduce the retraction time of the upper canine following extraction of upper maxillary premolars for patients with bimaxillary protrusion. HYPOTHESIS: No change on comparing the values of blood inflammatory markers before and after submucosal injection of PRP. METHODS: Eighteen female patients with bimaxillary protusion were selected from patients seeking orthodontic treatment from the College of Dentistry/University of Sulaimai, whose maxillary and mandibular first premolars were decided to be extracted after proper diagnosis. Thirty-three blood markers (twenty hematological and thirteen biochemical markers) were estimated before orthodontic bracketing, 24 hours and 7 days following submucosal injection of PRP (5 cc) to reveal the systematic effect of PRP on blood inflammatory markers that were used in an attempt to reduce the retraction time of the upper canine following extraction of upper maxillary premolars for patients with bimaxillary protrusion. RESULTS: The results indicate nonsignificant differences in the values of all blood markers except for gamma GT (GGT), PDWa, serum albumin, serum total protein, and total calcium. Gamma level significantly increased for both test intervals. On the other hand, there was a significant drop in the value of PDWa while for alkaline phosphatase, there was a drop within the first 24 hr of PRP injection while after 7 days the value was significantly increased. On the other hand, there was a drop in the level of serum albumin, while there was an increase in the serum total protein and total calcium. CONCLUSION: Submucosal injection of PRP could lead to systematic alteration of blood parameters including ALK phosphatase, gamma GT, serum albumin, and serum total protein, which may be related to liver function in addition to increase in the level of PDWa and serum calcium. We present evidence that PRP contains and may trigger systemic effect. Thus, further investigation is recommended to follow up the patient for a longer period of time and on a larger sample. This trial is registered with U1111-1221-8829 by Sri Lanka Clinical Trial Registry, SLCTR/2018/040, and No. 64 on 6th August 2018 at the local clinical studies database, College of Dentistry.
