[Use of trental for correction of disorders in the system of hemostasys in patients with fibro-cavernous tuberculosis and chronic pulmonary heart].

The effect of trental on hemostasys system depending on the degree of heart failure was studied in patients with fibrocavernous pulmonary tuberculosis complicated by chronic pulmonary heart disease. Established the desirability of placing trental in the treatment regimen of patients with fibrocavernous pulmonary tuberculosis and compensated CPHD in order to correct violations of the microcirculation and prevention of circulatory decompensation.

[The composition of the cerebrospinal fluid in children with tuberculous meningitis with different patterns of the mycobacterial population]. / Sostav spinnomozgovoi zhidkosti detei, bol'nykh tuberkuleznym meningitom, pri razlichnom kharaktere mikobakterial'noi populiatsii.

Composition of the liquor with regard of mycobacterial population was investigated in 113 children with tuberculosis meningitis. The changes in the liquor were most pronounced in bacterial variant of the causative agent and were minimal in the absence of both bacterial and L-forms of M. tuberculosis. This, however, does not mean that tuberculosis etiology of meningitis is ruled out.

[Morphological heterogeneity and functional status of the alveolar macrophages from bronchoalveolar lavage during the development of tuberculous inflammation in guinea pigs]. / Morfologicheskaia geterogennost' i funktsional'nyi status al'veoliarnykh makrofagov bronkhoal'veoliarnogo lavazha pri razvitii tuberkuleznogo vospaleniia u morskikh svinok.

Alveolar macrophages (AM) isolated from bronchoalveolar lavage of guinea pigs obtained in the course of generalized tuberculosis development was studied by electron microscopy. The protein content, activity of cathepsins B and D, as well as macrophage and neutrophil elastase activity have been determined. It was shown that during the first month of specific process development an influx of young biosynthesizing AM building up the lysosomal apparatus was observed; phagocytic, digesting and secretory functions of mature cells were enhanced. Progressing of tuberculosis was accompanied by the inhibition of biosynthetic processes in AM, a decrease in digesting and secretory functions, which were manifested at the biochemical and then at the electron microscopic levels and were of a prognostic value.