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1.
Chest ; 130(4): 1138-42, 2006 Oct.
Article in English | MEDLINE | ID: mdl-17035448

ABSTRACT

BACKGROUND: Chylothorax occurring during thoracic aortic surgery is an infrequent but serious complication. The purpose of this study was to analyze our experience with this complication and the resulting outcomes. METHODS: From January 1991 to July 2005, we performed 1,233 descending thoracic and thoracoabdominal aortic surgical procedures. A retrospective review was performed to analyze and identify preoperative and operative risk factors as well as management outcomes of postoperative chylothorax (PCT). RESULTS: PCT developed in five patients (0.4%). All five cases occurred with descending thoracic aortic aneurysm repair, and 80% (four of five patients) were undergoing aortic reoperation. All patients were managed successfully with no mortality. Risk factors for the development of chylothorax were descending thoracic aortic repair (p = 0.006) and thoracic aortic reoperations (p = 0.0003). Nonoperative management was successful in 60% (three of five patients). Two patients required left thoracotomy with direct ligation. Mean hospital length of stay was 35 days (range, 15 to 60 days). Mean follow-up was 33 months (range, 3 to 69 months) with no recurrence of chylothorax or additional morbidity or mortality. CONCLUSIONS: Chylothorax is more likely to occur with reoperations and repairs involving the descending thoracic aorta. Although PCT is associated with longer hospital length of stay, it is not associated with increased infectious complications. Early identification and prompt treatment may decrease both early and late morbidity and mortality.


Subject(s)
Aortic Aneurysm, Abdominal/surgery , Aortic Aneurysm, Thoracic/surgery , Aortic Dissection/surgery , Chylothorax/etiology , Postoperative Complications/etiology , Aged , Chylothorax/surgery , Drainage , Female , Humans , Length of Stay , Ligation , Male , Middle Aged , Parenteral Nutrition, Total , Postoperative Complications/surgery , Reoperation , Retrospective Studies , Risk Factors , Thoracic Duct/surgery , Thoracotomy
2.
Circulation ; 114(1 Suppl): I384-9, 2006 Jul 04.
Article in English | MEDLINE | ID: mdl-16820605

ABSTRACT

BACKGROUND: Currently, the optimal treatment of acute type B aortic dissection remains controversial. The purpose of this study was to report early clinical outcomes of medical management for acute type B aortic dissection. METHODS AND RESULTS: Between January 2001 and March 2005, 129 consecutive patients with the confirmed diagnosis of acute type B aortic dissection were studied. Mean age was 61 years (range, 29 to 94), with 33.3% (43/129) female. Acute type B aortic dissection protocol was instituted with the intent to manage all patients medically. Indications for surgical intervention included rupture, aortic expansion, malperfusion, and intractable pain. All patients were followed-up after discharge. Hospital mortality was 10.1% (13/129), 19% (4/21) when vascular intervention was required, and 8.3% (9/108) when medical management was maintained. Early intervention was required in 21 cases (16.2%), 19 (14.7%) open vascular/aortic cases and 2 cases (1.6%) of percutaneous aortic interventions. Morbidity included rupture (4.7%), stroke (4.7%), paraplegia (8.5%), bowel ischemia (7%), acute renal failure (21%), dialysis requirement (13%), and peripheral ischemia (4.7%). Late vascular-related procedures were performed in 5.2% (6/116) of cases. Univariate risk factors for early mortality were rupture (P<0.0001), need for laparotomy (P<0.008), acute renal failure (P<0.0001), need for dialysis (P<0.0001), and lower extremity ischemia (P<0.0004). The only independent risk factors for hospital mortality by multiple logistic regression was rupture (P<0.0009), and independent risk factors for midterm death were history of chronic obstructive pulmonary disease (P<0.002) and low glomerular filtration rate (<57 mL/min; P<0.0001). CONCLUSIONS: Medical management for acute type B aortic dissection is associated acceptable outcomes. Outcomes of other management strategies, eg, endovascular stenting, for acute type B aortic dissection need to be compared with these results.


Subject(s)
Antihypertensive Agents/therapeutic use , Aortic Aneurysm, Thoracic/drug therapy , Aortic Dissection/drug therapy , Acute Disease , Acute Kidney Injury/etiology , Acute Kidney Injury/therapy , Adult , Aged , Aged, 80 and over , Aortic Dissection/complications , Aortic Dissection/mortality , Aortic Dissection/surgery , Anticoagulants/therapeutic use , Aortic Aneurysm, Thoracic/complications , Aortic Aneurysm, Thoracic/mortality , Aortic Aneurysm, Thoracic/surgery , Aortic Rupture/etiology , Aortic Rupture/mortality , Aortic Rupture/surgery , Case Management , Critical Care , Disease Progression , Female , Follow-Up Studies , Hematoma/etiology , Hospital Mortality , Humans , Intestines/blood supply , Ischemia/etiology , Male , Middle Aged , Monitoring, Physiologic , Paraplegia/etiology , Prospective Studies , Pulmonary Disease, Chronic Obstructive/epidemiology , Renal Dialysis , Risk Factors , Stroke/epidemiology , Treatment Outcome , Venous Thrombosis/prevention & control
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