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1.
Three dinucleotide markers on chromosome 21.
de Souza, A P; Allamand, V; Richard, I; Brenguier, L; Beckmann, J S.
Hum Mol Genet ; 3(2): 381, 1994 Feb.
Article in English | MEDLINE | ID: mdl-8004115

Subject(s)
Chromosomes, Human, Pair 21 , Genetic Markers , Alleles , Base Sequence , Chromosome Mapping , DNA Primers , Gene Frequency , Humans , Molecular Sequence Data , Oligodeoxyribonucleotides
2.
Two dinucleotide repeats tightly linked to D12S91.
de Souza, A P; Allamand, V; Richard, I; Brenguier, L; Beckmann, J S.
Hum Mol Genet ; 3(2): 382, 1994 Feb.
Article in English | MEDLINE | ID: mdl-8004117

Subject(s)
Chromosomes, Human, Pair 12 , Genetic Markers , Polymorphism, Genetic , Repetitive Sequences, Nucleic Acid , Alleles , Base Sequence , DNA Primers , Gene Frequency , Genetic Linkage , Humans , Molecular Sequence Data , Oligodeoxyribonucleotides
3.
Targeted development of microsatellite markers from inter-Alu amplification of YAC clones.
de Souza, A P; Allamand, V; Richard, I; Brenguier, L; Chumakov, I; Cohen, D; Beckmann, J S.
Genomics ; 19(2): 391-3, 1994 Jan 15.
Article in English | MEDLINE | ID: mdl-8188274

ABSTRACT

Primary genetic maps based on highly informative markers are now available. The local density of these markers may, however, not be sufficient. There is thus a need for new means to generate polymorphic markers from targeted regions of the genome. This can be achieved by selectively cloning and sequencing (CA)n-positive human inter-Alu sequences from targeted YAC clones. This method was tested on 21 YACs and led to the development of seven new polymorphic microsatellite markers.


Subject(s)
Chromosome Mapping/methods , DNA, Satellite/genetics , Genetic Markers , Base Sequence , Chromosomes, Artificial, Yeast , Cloning, Molecular , Gene Amplification , Humans , Molecular Sequence Data , Polymerase Chain Reaction , Polymorphism, Genetic , Repetitive Sequences, Nucleic Acid
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