ABSTRACT
Two domestic shorthair cats (6 and 9 months old) were presented for examination of ocular opacities. One cat had bilateral persistent pupillary membranes, unilaterally accompanied by persistent hyperplastic tunica vasculosa lentis, persistent hyperplastic primary vitreous (PHTVL/PHPV), and cataract. The second cat had bilateral PHTVL/PHPV with dense white plaques in the posterior lens capsule and subcapsular cortex.
Subject(s)
Cat Diseases/diagnosis , Eye Abnormalities/veterinary , Lens, Crystalline/abnormalities , Vitreous Body/abnormalities , Animals , Cat Diseases/congenital , Cat Diseases/diagnostic imaging , Cat Diseases/pathology , Cats , Diagnosis, Differential , Eye Abnormalities/diagnosis , Hyperplasia/veterinary , Male , UltrasonographyABSTRACT
OBJECTIVE: To review 12 cases of histologically confirmed feline eosinophilic conjunctivitis, their clinical, cytologic, histologic and electronmicroscopic findings, results on PCR for FeHV-1, treatment and outcome. ANIMALS STUDIED: Twelve naturally occurring cases presented during a period of 26 months. PROCEDURES: Thorough ophthalmologic examination, conjunctival scrapings performed with the cytobrush method; histologic samples from the palpebral conjunctiva; PCR for FeHV-1 on Schirmer Tear Test (STT) strips; saliva and nasal swabs, and retrospective evaluation of all results. RESULTS: The breed most commonly affected was the Domestic Shorthair (n = 8), followed by Persians (n = 2), Somali (n = 1) and Siamese (n = 1). Age at presentation was 1-15 years with a mean age of 7.2 years. Nine cats were castrated males; three cats were females: two of them were spayed. Unilateral (n = 7) or bilateral (n = 5) involvement with depigmentation and erosions of lid margin, blepharospasm, swelling and redness of conjunctiva and third eyelid were the most common clinical findings. Frequency of eosinophils in cytologic samples was more than 10% in every patient. PCR for FeHV-1 on STT was negative in all cases. Histologically, eosinophils, lymphocytes, plasma cells, mast cells and macrophages were involved. On electronmicroscopy, viral particles were not detected. Ten cases needed long-term anti-inflammatory treatment. CONCLUSIONS: The 12 reviewed cases suggest that feline eosinophilic conjunctivitis is a chronic inflammatory uni- or bilateral disease of the adult cat. Typically the lid margin was also involved, and was thickened, depigmented and erosive. Cytological examination of conjunctival scrapings was a valuable tool for detecting eosinophilic conjunctivitis. The cytological findings correlated well with the histopathological findings in our patients. Topical or systemic anti-inflammatory drugs resolved the clinical symptoms in our cases within a short period of time. Neither electronmicroscopy nor PCR were able to detect involvement of FHV1 in the represented cases. The etiopathogenic role of FeHV-1 remains undetermined.
Subject(s)
Cat Diseases/diagnosis , Conjunctivitis/veterinary , Eosinophilia/veterinary , Animals , Anti-Inflammatory Agents/therapeutic use , Cat Diseases/drug therapy , Cat Diseases/pathology , Cat Diseases/virology , Cats , Conjunctivitis/diagnosis , Female , Herpesviridae/genetics , Herpesviridae/isolation & purification , Male , Polymerase Chain Reaction/veterinaryABSTRACT
The magnetic resonance imaging appearance of the feline middle ear is described in three healthy cats and in five cats with middle ear disease. Owing to the good spatial resolution, multiplanar slice orientation as well as display high contrast resolution of soft tissue, in particular fluids, MR imaging was helpful prior to surgery. It is superior to radiography which failed to allow identification of the abnormality in two of our five cats. MR imaging for middle ear disease should include dorsal and transverse plane images using T1- and T2-weighted sequences. In the presence of a mass within the bulla or the external ear canal application of contrast medium is helpful.
Subject(s)
Cat Diseases/diagnosis , Magnetic Resonance Imaging , Otitis Media/veterinary , Animals , Cat Diseases/pathology , Cat Diseases/surgery , Cats , Ear, Middle/anatomy & histology , Female , Male , Osteotomy , Otitis Media/diagnosis , Otitis Media/pathology , Otitis Media/surgeryABSTRACT
Ten cases of uni- or bilateral restrictive ventromedial strabismus in young dogs of different breeds are reported. Clinically, abnormalities were restricted to the extraocular muscles with sparing of the masticatory muscles and limb muscles. This was supported in some cases by imaging studies, electrophysiology, and immunocytochemical assay for antibodies against type 2M fibers. Histologically, there was variable lymphocytic plasmacytic mononuclear cell infiltration and fibrosis. This disorder is similar in many aspects to chronic masticatory myositis with focal myositis and subsequent fibrosis. Surgical correction may restore eye position and vision.
ABSTRACT
A guinea pig with multicentric lymphosarcoma and conjunctival manifestation is described. Primary clinical signs were bilateral infiltrative conjunctival masses. Antemortem diagnosis was based on the cytology of biopsies of conjunctival tissue, fine-needle aspirates of peripheral lymph nodes, and peripheral blood smears.
ABSTRACT
A case of a 6.5-year-old castrated male European Shorthair Cat with an unilateral lesion of the oculomotor nerve is described. Nuclear magnetic resonance imaging revealed a mass in the area of the pituitary gland which could be identified as a somatotrope adenoma by immunochemistry. Unlike the feline somatotrope adenoma cases described in the literature this cat showed clinically no acromegalic features or hyperglycemia. An oculomotor nerve lesion in conjunction with a feline somatotropic pituitary adenoma has also not been described before.
