[Psychophysiology of suicide in prison: a contribution in terms of prevention]. / Psicofisiopatologia del suicidio in carcere: un contributo in termini di prevenzione.

Suicide in detention environment is a phenomenon that affects both prisoners and operators, especially prison service. Currently, in terms of suicide prevention, the interest is shifting from an etiology essentially endogenous to exogenous factors, seeing as the criticality of system has its origin in the lack of knowledge of the "detained person". This work neglects statistics and detection models to look at all those behaviors that are part of suicide, although the suicidal act is not genuine. This view allows to identify areas of risk and it is not just for have a look over "the death event". Aware that no definition is enough to shed light on this phenomenon where subjectivity is elusive, we must always bear in mind the behaviors that precede it and exogenous and endogenous factors. To better understand the phenomenon of suicide in prison it is necessary to be aware of the action that a "totalizing institution" has on the individual.

[Pharmacotherapy in the treatment of borderline personality disorder]. / Farmacoterapia nel trattamento del disturbo borderline di personalità.

The aim of this study is to bring together the previous studies on pharmacotherapy of borderline disorder from the oldest to the recent ones, mainly focusing on atypical antipsychotic, whose success has been underlined in recent medical literature with peculiar reference to olanzapine. Since the '80 the pharmacotherapy in borderline personality disorder has been playing an increasing role in the interest of scientific community and in the medical practice as indicated by APA guidelines (2000). Nowadays the pharmacological approach, supported by some experimental outcomes, follow a so called "dimensional" standard. The targets of this standard drug approach are specific psychopathological "dimensions" of the disorder and related neurotransmitters' changes in particular linked to serotoninergic and dopaminergic systems, both supported by experimental outcomes. The psychopathological dimensions to which pharmacological approach is more suitable are: impulsiveness and emotional dysregulation. During the last past years, effectiveness of atypical antipsychotic drugs became of major interest in medical treatment of borderline disorder, mainly related to their action toward the serotoninergic and dopaminergic systems.