Moving forward with a culturally inclusive PTSD Criterion A: Commentary on Marx et al. (2023).

In response to Marx et al.'s (2023) article, "The PTSD Criterion A debate: A brief history, current status, and recommendations for moving forward," this commentary offers agreement with the recommendation to conduct population-based studies to inform future Criterion A changes. However, to fully address the debate as to whether Criterion A should be expanded, limited, eliminated, or remain unchanged, it is critical that future population-based research focus on cultural inclusivity and the addition of potentially traumatic experiences that are collective and/or cumulative versus individual and discrete. To further understand the etiology of mental health distress and disorder and the role of adverse life experiences, it is also recommended that adverse event specifiers be added to disorders not currently considered to be event-related. The ability to identify the potential long-term effects of adverse life experiences in relation to disorders other than posttraumatic stress disorder (e.g., major depressive disorder) could help validate experiences, reduce stigma, and further advance research on etiology and interventions.

Parallel processes of posttraumatic stress and cardiometabolic dysfunction: A systemic illness of traumatic stress.

OBJECTIVE: To determine if and how cardiometabolic conditions (MetC) may be associated with posttraumatic stress disorder (PTSD) symptoms over time when controlling for the influence of potentially confounding variables. METHOD: Parallel process latent growth modeling was applied to self-reported longitudinal data collected from 35,788 World Trade Center 9/11 survivors to determine how the development and course of PTSD symptoms and MetC influence each other when controlling for age, sex, race/ethnicity, preexisting traumas, physical health problems, general psychological distress, smoking, and alcohol use. RESULTS: A unidirectional relationship was found in which the intercept of PTSD symptoms predicted the slope of MetC. Hyperarousal (ß = .172) and emotional numbing (ß = .171) PTSD symptoms demonstrated the strongest association with MetC changes over and above the effects of control variables and potential confounders. Post hoc analyses indicated that utilization of PTSD-related psychotherapy was associated with decreased early presentations of MetC following trauma, which may have vital implications for the integrated treatment of trauma-exposed individuals. CONCLUSIONS: Findings have strong theoretical and clinical implications for conceptualizing traumatic stress reactions as systemic processes and utilizing integrated treatment practices following psychological trauma. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The Middle-Out Approach to reconceptualizing, assessing, and analyzing traumatic stress reactions.

Alternative models of traumatic stress and broader psychopathology have been proposed to address issues of heterogeneity, comorbidity, clinical utility, and equitable representation. However, systematic and practical methods and guidelines to organize and apply these models remain scarce. The Middle-Out Approach is a novel, integrative, contextually informed framework for organizing and applying existing empirical methods to evaluate current and alternative traumatic stress reactions. Rather than beginning to identify traumatic stress reactions from the top-down (i.e., disorder-first approach) or bottom-up (i.e., symptom-first approach), constructs are evaluated from the middle out (i.e., presentation-first approach), unconstrained by higher-order disorders or lower-order diagnostic symptoms. This approach provides innovation over previous methods at multiple levels, including the conceptualization of traumatic stress reactions as well as the type of assessments and data sources used and how they are used in statistical analyses. Conceptualizations prioritize the identification of middle-order phenotypes, representing person-centered clinical presentations, which are informed by the integration of multidimensional, transdiagnostic, and multimodal (e.g., psychosocial, physiological) assessments and/or data sources. Integrated data are then analyzed concurrently using person-centered statistical models to identify precise, discrete, and representative health outcomes within broader heterogeneous samples. Subsequent variable-centered analyses are then used to identify culturally sensitive and contextually informed correlates of phenotypes, their clinical utility, and the differential composition within and between broader traumatic stress reactions. Examples from the moral injury literature are used to illustrate practical applications that may increase clinical utility and the accurate representation of health outcomes for diverse individuals and communities.

Youth Exposure to Gun, Knife, and Physical Assaults: Assessing PTSD Symptoms Across Types of Assaults, Race, Ethnicity, Sex, and Context.

This study examined posttraumatic stress disorder (PTSD) symptoms in relation to physical assaults and weapons-related victimization, as well as the moderating roles of demographic characteristics and the context of victimization. The sample consisted of 910 racially and ethnically diverse adolescents and young adults from an urban commuter college in the Northeast U.S. Findings include significant sex differences and racial differences in reported victimization and symptoms. Men reported significantly more physical assaults, gun victimizations, and knife victimizations than women. Black participants reported significantly more gun victimization than all other groups, and Black, White, and Asian participants reported significantly more physical assault experiences than Latinx participants. Individuals victimized by physical assault or by gun victimization were more than twice as likely to report clinically significant PTSD symptoms than individuals without such experiences, even after adjusting for demographic differences. In addition, for gun victimization in the community, a two-way interaction (gun victimization by race) and a three-way interaction (gun victimization by race by sex) were significantly associated with clinically significant PTSD symptoms. Gun victimization in the community, which disproportionately impacts Black men, was the only context in which PTSD symptoms were highest for men compared to women. The overall finding of lower PTSD symptoms among men suggests that clinical practice must include an intentional focus on violence victimization, including the use of weapons, as well as the various ways that distress might manifest among men. In addition to symptoms of PTSD, other symptoms of distress, including substance use, anger, and retaliatory aggression, should be considered. Public policy and public health must also direct attention to the use of weapons in violence victimization and the proliferation of weapons violence.

Introduction to the Special Issue: Disproportionate trauma, stress, and adversities as a pathway to health disparities among disenfranchised groups globally.

Globally, individuals and communities that are marginalized based on their identities are at heightened risk for exposure to traumatic stress and socioeconomic hardship. Marginalization and disproportionate risk for many types of adversities correspond with disparities in physical health, mental health, and overall well-being. Together, the 12 empirical studies, one systematic review, and commentary in this special issue of the Journal of Traumatic Stress highlight the impact of discrimination and disproportionate adversity among groups marginalized based on race, ethnicity, nativity, caste, gender identity, sexual orientation, economic status, and medical status. Although most studies in this issue focus on the United States, the articles that focus on disparities and risk factors in India, El Salvador, Uganda, and Burundi provides a multicontinent global perspective. The global perspective, including the impact of the global pandemic, invites further examination of how disproportionate exposure to traumatic stress and adversity are associated with inequitable burden and health disparities worldwide. This special issue further highlights the developmental and multigenerational burden of systemic marginalization by including studies of children, young adults, adults, and parent-child dyads. Pathways for change and intervention are illustrated through a liberatory consciousness perspective, with one study utilizing liberatory media skills (e.g., positive media images and messages) to mitigate the adverse effects of trauma exposure on at-risk young adults of color. Worldwide, research on the effects of trauma, stress, and adversities must examine contextual factors (e.g., economic hardship), marginalization (e.g., discrimination, identity factors), and the differential impact on health among individuals and communities.

Profiles of home violence and posttraumatic stress symptoms among young adults: Distinguishing between trauma and adversity using latent class analysis.

OBJECTIVE: Home violence exposure (HVE) varies by type and frequency of exposure, which can lead to uncertainty when determining what is traumatic and what is not, particularly when assessing posttraumatic stress symptoms (PTSS) and disorder (PTSD). The current study examined whether specific types of HVE were associated with specific types of PTSS to help determine what experiences may rise to the level of trauma. METHOD: Participants included 988 racially and ethnically diverse college students (74.1% women). Two latent class analyses were performed, examining types of HVE and types of PTSS to determine how classifications of HVE were associated with classifications of PTSS. RESULTS: Four classifications of HVE were identified: high exposure (21.7%), vicarious exposure (28.9%), victimization (10.5%), and low exposure (38.9%). Four classifications of PTSS were also identified: high PTSS (20.9%), dysphoric arousal (17.4%), anxious arousal (21.3%), and low PTSS (40.4%). Even when considering other potentially traumatic events, participants with experiences of victimization were 2.55 times more likely than those with low exposure to meet criteria for PTSD. Victimization was uniquely associated with dysphoric arousal as well as all other PTSS. High exposure was associated with high PTSS and anxious arousal, with vicarious exposure associated only with anxious arousal. CONCLUSIONS: Findings provide unique evidence for the potentially traumatic effects of victimization in the home. Frequent and cumulative effects of HVE that do not meet DSM criteria for a potentially traumatic event may be associated with elevated PTSS, particularly symptoms of anxious and dysphoric arousal. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Developmental and Measurement Implications of Using the UCLA PTSD Reaction Index with College Students.

Studies measuring Posttraumatic Stress Disorder (PTSD) symptoms from childhood into adulthood have been hampered by use of different measures across different developmental stages. Use of one measure across age groups would reduce measurement error and strengthen our understanding of the developmental progression of trauma. Thus, this study examined whether the UCLA PTSD Reaction-Index (PTSD-Index), which was developed for use with children and adolescents (aged 7 to 18), could be used with young adults. The utility of the measure was examined among three age groups of college students (17-18, 19-20, and 21-25). Sex differences and race/ethnicity differences were also examined. Findings indicate that the PTSD-Index is internally consistent and reliable when used with college students. Furthermore, the factor structure for the measure is similar for adolescents and for emerging adults. In sum, the PTSD-Index appears to be an appropriate screener for PTSD symptoms among young adults. The findings are relevant for both the DSM-IV and DSM-5 screening measures, and the findings have both research and clinical implications. The findings are particularly important for longitudinal studies that are challenged with addressing developmental progression of PTSD symptoms among participants, while also addressing changes in the PTSD nosology.

Time and support do not heal all wounds: Mental health correlates of past bullying among college students.

Objective: We examined whether perceptions of being bullied during middle and high school were associated with depressive, anxiety, and posttraumatic stress disorder (PTSD) symptoms during college. We also examined whether perceived social support (PSS) mediated the association between bullying and symptoms, and explored whether parental, peer, or other sources of support was most beneficial. Participants: Undergraduates (N = 270) from an urban commuter college in the Northeast participated during Spring 2013 or Fall 2015. Methods: Psychometrically sound self-report measures were used to assess symptoms and perceptions of bullying and social support. Results: As hypothesized, bullying was associated with more symptoms, and PSS significantly mediated the associations between bullying and symptoms of PTSD and depression. Conclusion: The college years provide another opportunity to address the effects of middle and high school bullying. Receiving current support for past bullying is beneficial but is not enough, college counseling services are needed to reduce symptoms.

Posttraumatic Stress Trajectories in World Trade Center Tower Survivors: Hyperarousal and Emotional Numbing Predict Symptom Change.

There is a paucity of knowledge concerning the underlying symptomatology of heterogeneous posttraumatic stress symptom (PTSS) trajectories following mass trauma, such as a terrorist attack. This study examined longitudinal PTSS trajectories using latent growth mixture modeling in 2,355 World Trade Center (WTC) tower survivors surveyed by the WTC Health Registry an average of 2.5, 5.5, and 10.5 years after the September 11, 2001 terrorist attacks. Covariates included sociodemographic characteristics, WTC-related exposure, and other traumas/stressors. Four curvilinear PTSS trajectories were identified: low symptom (74.9%), recovering (8.0%), worsening (6.7%), and chronic (10.4%). The majority of WTC survivors (85.3%) maintained stable symptom trajectories over time, with PTSS changes occurring less often. Although WTC-related exposure was associated with initial PTSS severity, exposure was not associated with chronicity or change of PTSS over time. Male gender and a higher number of post-WTC disaster life-stressors were associated with worsening symptom severity over time. Individuals with more severe hyperarousal symptoms at Wave 1, particularly of anxious arousal, were more likely to have PTSS that worsened over time, adjusted odds ratio (aOR) = 1.55. Less severe emotional numbing symptoms, particularly of dysphoria, at Wave 1, were marginally significantly associated with subsequent PTSS recovery, aOR = 0.75. Interventions that target hyperarousal and emotional numbing symptoms may mitigate a worsening of symptoms and facilitate posttraumatic recovery following future mass traumas, such as terrorist attacks. Further clinical implications are discussed.

Spanish Abstracts by Asociación Chilena de Estrés Traumático (ACET) Trayectorias de estrés postraumático en sobrevivientes de la torre del World Trade Center: Hiperactivación y adormecimiento emocional predicen un cambio en los síntomas TRAYECTORIAS DE TEPT RELACIONADAS CON EL WORLD TRADE CENTER Existe una escasez de conocimientos sobre la sintomatología subyacente de las trayectorias heterogéneas de los síntomas de estrés postraumático (TEPT) después de un trauma masivo, como un ataque terrorista. Este estudio examinó las trayectorias longitudinales de TEPT utilizando modelos de mezcla de crecimiento latente en 2.355 sobrevivientes de las torres del World Trade Center (WTC), encuestados por el Registro de Salud de WTC con un promedio de 2.5, 5.5 y 10.5 años después de los ataques terroristas del 11 de septiembre de 2001. Las covariables incluyeron características sociodemográficas, exposición relacionada con el WTC y otros traumas/factores estresantes. Se identificaron cuatro trayectorias curvilíneas de TEPT: síntomas bajos (74.9%), recuperación (8,0%), empeoramiento (6,7%) y crónico (10,4%). La mayoría de los sobrevivientes del WTC (85.3%) mantuvieron trayectorias de síntomas estables a lo largo del tiempo, con cambios en TEPT que ocurren con menos frecuencia. Aunque la exposición relacionada con el WTC se asoció con la gravedad inicial del TEPT, la exposición no se asoció con la cronicidad o el cambio del TEPT a lo largo del tiempo. El género masculino y un mayor número de factores estresantes de vida después del WTC se asociaron con el empeoramiento de la gravedad de los síntomas con el tiempo. Las personas con síntomas de hiperactivación más severos en la primera evaluación (1), particularmente de agitación ansiosa, tenían más probabilidades de tener TEPT, el cual empeoró a través del tiempo, la razón de probabilidades ajustada (aOR) = 1.55. Los síntomas de adormecimiento emocional menos severos, particularmente de disforia, en la primera evaluación (1), se asociaron marginalmente de manera significativa con la recuperación subsecuente de TEPT, aOR = 0.75. Las intervenciones dirigidas a los síntomas de hipersensibilidad y adormecimiento emocional pueden mitigar el empeoramiento de los síntomas y facilitar la recuperación postraumática después de futuros traumas masivos, como los ataques terroristas. Se discuten las implicaciones clínicas.

Stress through the mind of the beholder: preliminary differences in child and maternal perceptions of child stress in relation to child cortisol and cardiovascular activity.

The present study examined associations among parent and child reports of youth's stressful life events (SLEs), perceived stress, and biological measures of stress activity (i.e. cortisol and cardiovascular activity). Examining these aspects of youth stress presents several challenges. Unlike adult studies of individual differences in which information regarding SLEs, perceptions of events, and biological activity are gathered from one individual, assessment of individual differences among children usually involves other informants (e.g. parent). However, parent and child reports of SLEs and the child's psychological response to such events are often discordant. Moreover, examinations of youth perception of stress are hampered by limitations of child cognitive processes, as well as parents' limited knowledge of their child's perception of stress. In a preliminary effort to unscramble the complex effects of youth SLEs and perceived stress in relation to biological response to acute stressors, this study examined 51 boys and girls aged 7-16, with no history of psychopathology or medical concerns. Contrary to hypotheses, findings revealed that compared to actual experiences of stress, perceived stress has greater associations with both cortisol and cardiovascular activity. That is, perceived stress is more biologically salient relative to actual stress. Results also suggest that informant differences may explain some previous inconsistent findings in studies of youth's stress reactivity. The current findings mirror the adult studies that show appraisal and perception of traumatic and stressful events may be more predictive of negative health and mental health outcomes than the severity of the events. Further studies are needed to understand the impact of youth's perceptions of stress on their biological stress reactions and later health outcomes such as clinical disorders.

Negative cognitions as a moderator in the relationship between PTSD and substance use in a psychiatrically hospitalized adolescent sample.

Adolescents exposed to trauma are more likely to engage in alcohol and marijuana use compared to their nontrauma-exposed counterparts; however, little is known about factors that may moderate these associations. This study examined the potential moderating effect of cognitions relevant to exposure to trauma (i.e., negative view of self, world, and future) in the association between posttraumatic stress disorder (PTSD) diagnosis and substance use among a psychiatric inpatient sample of 188 adolescents. Findings were that PTSD diagnosis was not significantly associated with substance-use diagnoses, but was associated with substance-use symptoms, accounting for 2.9% and 9.6% of the variance in alcohol and marijuana symptoms, respectively. The association between PTSD diagnosis and substance use symptoms, however, was moderated by negative cognitions, with PTSD and high negative cognitions (but not low negative cognitions) being significantly positively associated with substance use symptoms. The relevant cognitions differed for alcohol symptoms and marijuana symptoms. Children and adolescents who experience trauma and PTSD may benefit from early interventions that focus on cognitive processes as one potential moderator in the development of posttrauma substance use.

Posttrauma numbing of fear, detachment, and arousal predict delinquent behaviors in early adolescence.

This study elaborated on associations between youth's trauma-related emotional numbing across multiple affective domains (e.g., fear, sadness, happiness, anger) and delinquent behaviors. The study also examined whether the effects of posttrauma emotional numbing varied by the occurrence of posttrauma arousal symptoms. Participants were 123 middle school boys and girls from working-class, urban communities. Emotional numbing, particularly diminished fear, was related to both home and community violence exposure. Numbing of fearful emotions was associated with all types of delinquent behaviors examined. In addition, numbing of sadness was associated with aggression. Interactions between numbing of fear and hyperarousal suggested a complex pattern of emotional processing following exposure to traumatic events in which numbing related to delinquent behavior only in the context of high posttrauma arousal. These patterns may coalesce to place youth at risk for early involvement in delinquent behaviors.

Direct and moderating links of salivary alpha-amylase and cortisol stress-reactivity to youth behavioral and emotional adjustment.

Recent studies have revealed evidence for interactions between autonomic nervous system (ANS) activity, indexed by saliva alpha amylase (sAA), and hypothalamic-pituitary-adrenocortical activity, in predicting psychological functioning. The present study extends this work by examining individual differences in sAA and cortisol stress reactivity in relation to behavioral and emotional adjustment in youth. Participants were 56 healthy children (age 7-16). sAA, cortisol, and other physiological and affective responses were measured before, during, and after stressor tasks (either performance or peer rejection). Basal and stress responsive sAA and cortisol as well as their interactions were assessed in relation to externalizing and internalizing behaviors and trait anxiety. sAA was positively related to anxiety, while sAA reactivity moderated associations between cortisol reactivity and problem behavior. Results highlight the importance of measuring multiple physiological systems to elucidate mechanisms underlying behavioral and emotional dysregulation.

Social information processing in children: specific relations to anxiety, depression, and affect.

Two studies examined shared and unique relations of social information processing (SIP) to youth's anxious and depressive symptoms. Whether SIP added unique variance over and above trait affect in predicting internalizing symptoms was also examined. In Study 1, 215 youth (ages 8-13) completed symptom measures of anxiety and depression and a vignette-based interview measure of SIP. Anxiety and depression were each related to a more negative information-processing style. Only depression was uniquely related to a less positive information processing style. In Study 2, 127 youth (ages 10-13) completed measures of anxiety, depression, SIP, and trait affect. SIP's relations to internalizing symptoms were replicated. Over and above negative affect, negative SIP predicted both anxiety and depression. Low positive SIP added variance over and above positive affect in predicting only depression. Finally, SIP functioning partially mediated the relations of affect to internalizing symptoms.

The Children's Evaluation of Everyday Social Encounters Questionnaire: comprehensive assessment of children's social information processing and its relation to internalizing problems.

Two studies describe the development of a comprehensive, vignette-based measure of social information processing (SIP) particularly relevant for children with internalizing problems. Study 1 (N = 219 3rd-6th graders) describes the creation of the Children's Evaluation of Everyday Social Encounters Questionnaire (ChEESE-Q) and evidence for its reliability and validity, including internal structure and relation of SIP variables to depressive and anxious symptoms. Study 2 (N = 127 5th-6th graders) replicated the factor structure and validity evidence found in Study 1 and provided support for the reliability of alternate forms of the ChEESE-Q. Overall, results supported ChEESE-Q scores' moderate temporal stability and internal consistency in assessing SIP. Results also supported the presence of positive- and negative-valenced SIP patterns. Child internalizing symptoms were strongly related to a negative SIP style across both depression and anxiety, whereas only depressive symptoms were negatively associated with positive aspects of SIP.

Children's trauma and adjustment reactions to violent and nonviolent war experiences.

OBJECTIVE: According to most studies, more than half of children exposed to war meet criteria for posttraumatic stress disorder (PTSD). Although we know that children are adversely affected by atrocities of war, we do not know which specific war events are associated with children's stress reactions. For example, it is unclear whether differences exist in response to violent versus nonviolent war-trauma experiences. This study examined the relationship of violent and nonviolent war experiences to children's trauma reactions and adjustment in a group of children from Bosnia. METHOD: During the 1994 siege in Sarajevo, 791 children aged 6 to 16 years participated in a study of trauma experience and response, in which assessment questionnaires (Impact of Event Scale, PTSD Reaction Index, Children's Depression Inventory, Child Behavior Checklist, and War Experience Questionnaire) were completed by children and their teachers. RESULTS: In this sample 41% had clinically significant PTSD symptoms. Children were adversely affected by exposure to both violent and nonviolent war-traumas. An additive effect of trauma exposure on trauma reactions was also found. However, many war experiences were not associated with children's adjustment and trauma reactions. CONCLUSIONS: Additive effects of violence and deprivations during war may overwhelm the coping skills of children and leave them vulnerable to externalizing and internalizing adjustment difficulties and symptoms of PTSD.