Subject(s)
Thromboangiitis Obliterans/therapy , Adult , Amputation, Surgical , Hemodilution , Hemodynamics , Heparin/therapeutic use , Humans , Male , Middle Aged , Smoking , Sympathectomy, Chemical , Thromboangiitis Obliterans/etiology , Thromboangiitis Obliterans/pathology , Vasodilator Agents/therapeutic useABSTRACT
The effect of pharmacological doses of synthetic salmon calcitonin (CT) on the healing of experimental wounds in rats is studied. Subcutaneous administration of 20 IU/Kg body weight/day induces a significant increase in collagen content in the scars of treated animals at five, eight, ten and 15 days, as compared with the scars of non-treated animals. The scars of the treated animals also showed a greater tensile strength (TS) than those of the control group, except on day 8.
Subject(s)
Calcitonin/pharmacology , Wound Healing/drug effects , Animals , Cicatrix/metabolism , Collagen/metabolism , Hydroxyproline/metabolism , Rats , Rats, Inbred Strains , Skin/drug effects , Skin/metabolismABSTRACT
Ultrasound was used for the measurement of the flow of 50 dialysis fistulas. Mean flow was 806.2 ml/min. There was no difference between the flow of the different types of fistula. It has been observed that although the vein diameter determines the fistula flow, and the former continues to increase even after the fistula has matured, blood flow through the fistula does not increase as its velocity decreases with greater diameters. Flow measurements with ultrasound have important advantages and indications, which are commented.
Subject(s)
Arteriovenous Shunt, Surgical , Blood Circulation , Renal Dialysis , Ultrasonography , Adolescent , Adult , Aged , Blood Flow Velocity , Child , Female , Humans , Male , Middle AgedABSTRACT
With the help of the Doppler Ultrasound we have measured the radial artery blood flow of 20 healthy volunteers and the fistula flow of 40 uraemic patients. The measurements were made at rest and repeated one, three and five minutes after initiation of hand exercise, and one minute after the exercise had finished. Radial artery mean flow increased significantly with the exercise (p less than 0.001); radial arteries with greater baseline flow had less flow increase (p less than 0.002). However, we were not able to demonstrate any fistula flow increase with the hand exercise. Therefore, we conclude that there is no benefit in advising uraemic patients to squeeze a rubber ball which, otherwise, supposes an unnecessary preoccupation for these patients.
Subject(s)
Arteriovenous Shunt, Surgical , Blood Flow Velocity , Renal Dialysis , Adult , Female , Hand/physiopathology , Humans , Male , Middle Aged , Physical Exertion , UltrasonographyABSTRACT
We describe herein a technique by which surgical venous catheterization ("cut down") is easily and quickly performed with a minimal incision even in the obese patient or patient with shock, with the help of a slightly modified Doppler apparatus.
