ABSTRACT
The present report aimed to describe the main characteristics of the parotid salivary mucocele in an adult male rabbit, which presented with a painless fluctuating mass with fluid content. Owing to the need for repeated fluid drainage, surgical excision was the chosen mode of treatment. Preoperative evaluation included radiography and blood analysis. The patient underwent surgical excision of the affected gland. Inhalation anesthesia was maintained by means of isoflurane and the cardio-respiratory parameters were monitored throughout the surgery. A bipolar electrocautery was used to assist in the incision and polyglactin 910 and nylon were the suture materials used in the wound closure technique. Post-operative medications included analgesics, anti-inflammatory agents and antibiotics. Histopathology of the excised glandular tissue revealed a mixed inflammatory infiltrate, fibroblasts, hemorrhage and hyperemia. The observations in this case suggest that surgical excision of the affected gland is the treatment of choice for the management of mucocele in companion rabbits, which has already been identified for other animals. Periodic acid-reactive Schiff staining confirmed the diagnosis of salivary mucocele. The complementary investigations helped to rule out the differential diagnosis and indicated a favorable prognosis, in view of the fact that the case was successfully resolved without complications or recurrence.(AU)
O presente relato teve como objetivo descrever as principais características da mucocele salivar parotídea em um coelho macho adulto, que apresentou uma massa flutuante indolor e com um conteúdo líquido em seu interior. Devido à necessidade de repetidas punções deste fluido, optou-se pela excisão cirúrgica como forma de tratamento. A avaliação pré-operatória incluiu radiografias e análises sanguíneas. O paciente foi submetido ao tratamento cirúrgico com excisão da glândula afetada. A anestesia inalatória foi mantida com isoflurano e os parâmetros cardio-respiratórios foram monitorados durante a cirurgia. Um eletrocautério bipolar foi utilizado para auxiliar na incisão e os fios poliglactina 910 e nylon foram utilizados na técnica de sutura. As medicações pós-operatórias incluíram agentes analgésicos, anti-inflamatórios e antibióticos. A histopatologia do tecido glandular removido revelou infiltrado inflamatório misto, fibroblastos, hemorragia e hiperemia. As observações neste caso sugerem que a remoção cirúrgica da glândula afetada seja o tratamento de escolha no manejo da mucocele em coelhos de companhia, o que já vem sendo identificado para outros animais. A coloração do ácido periódico reativo de Schiff confirmou o diagnóstico da mucocele salivar. Os exames complementares ajudaram a excluir as doenças que fazem parte do diagnóstico diferencial e indicaram um prognóstico favorável, tendo em vista o fato que este caso foi resolvido com sucesso, sem complicações ou recorrência.(AU)
Subject(s)
Animals , Male , Rabbits , Salivary Glands/surgery , Parotid Region/surgery , Mucocele/veterinary , Periodic Acid-Schiff Reaction/veterinaryABSTRACT
Obstructive Sleep Apnoea Syndrome (OSAS) is believed to be associated with craniofacial and neuromuscular changes, although the interplay among these variables still is poorly recognised. The objective of this study was to identify hyoid, muscular and swallowing changes associated with OSAS, and to correlate these alterations with OSAS severity. Cross-sectional study, in a tertiary referral centre. Seventy-two adult individuals participated in this study: 12 controls (without apnoea) and 60 patients with apnoea (mild, moderate and severe OSAS-20 individuals in each group). All participants were initially evaluated by otorhinolaryngologist and neurologist and underwent polysomnography for OSAS stratification. Cephalometric data, clinical myofunctional status and swallow videofluoroscopy exam were assessed. A hybrid effect model was used to analyse swallowing parameters; dependent variables were age, body mass index (BMI) and cephalometric measures. Individuals with OSAS presented lower hyoid position and narrower posterior airway distance when compared to controls. These parameters correlated to OSAS severity. Additionally, OSAS patients exhibited significantly lower myofunctional scores. Both velum and hyoid contraction times were significantly lower in the OSAS group at videofluoroscopy, regardless of its severity. Premature leakage into pharynx was more common in OSAS groups. Laryngeal penetration phenomenon occurred only in two patients (both from OSAS group). Our results suggest that hyoid bone position is associated with OSAS severity. Muscular pattern and swallowing are impaired in OSAS patients, irrespective of OSAS severity and facial profile. These findings indicate a higher predisposition of OSAS patients to present an inferior hyoid positioning, accompanied by myofunctional and swallowing disorders.
Subject(s)
Cephalometry , Deglutition Disorders/physiopathology , Deglutition/physiology , Hyoid Bone/physiology , Polysomnography , Sleep Apnea, Obstructive/physiopathology , Adult , Body Mass Index , Cross-Sectional Studies , Deglutition Disorders/diagnostic imaging , Deglutition Disorders/etiology , Female , Fluoroscopy , Humans , Hyoid Bone/diagnostic imaging , Male , Pilot Projects , Severity of Illness Index , Sleep Apnea, Obstructive/complications , Sleep Apnea, Obstructive/diagnostic imagingABSTRACT
Background: Major abdominal oncology surgery is associated with substantial postoperative loss of functional capacity, and exercise may be an effective intervention to improve outcomes. The aim of this study was to assess efficacy, feasibility and safety of a supervised postoperative exercise programme. Methods: We performed a single-blind, parallel-arm, randomized trial in patients who underwent major abdominal oncology surgery in a tertiary university hospital. Patients were randomized to an early mobilization postoperative programme based on supervised aerobic exercise, resistance and flexibility training or to standard rehabilitation care. The primary outcome was inability to walk without human assistance at postoperative day 5 or hospital discharge. Results: A total of 108 patients were enrolled, 54 into the early mobilization programme group and 54 into the standard rehabilitation care group. The incidence of the primary outcome was nine (16.7%) and 21 (38.9%), respectively (P=0.01), with an absolute risk reduction of 22.2% [95% confidence interval (CI) 5.9-38.6] and a number needed to treat of 5 (95% CI 3-17). All patients in the intervention group were able to follow at least partially the exercise programme, although the performance among them was rather heterogeneous. There were no differences between groups regarding clinical outcomes or complications related to the exercises. Conclusions: An early postoperative mobilization programme based on supervised exercises seems to be safe and feasible and improves functional capacity in patients undergoing major elective abdominal oncology surgery. However, its impact on clinical outcomes is still unclear. Clinical trial registration: NCT01693172.
Subject(s)
Abdominal Neoplasms/rehabilitation , Abdominal Neoplasms/surgery , Exercise Therapy/methods , Exercise Tolerance , Program Evaluation/methods , Aged , Feasibility Studies , Female , Humans , Male , Middle Aged , Single-Blind Method , Treatment OutcomeABSTRACT
O objetivo deste trabalho foi estimar parâmetros genéticos de frutos, sementes e plântulas de Jatropha ribifolia (Pohl) Baill., subsidiando futuros programas de melhoramento e conservação genética. Foram selecionadas 20 matrizes da espécie e os frutos coletados em área de Caatinga, no Município de Jequié - BA / Brasil. Para descrição morfológica foram observadas características de 50 frutos e 50 sementes. Para germinação foi utilizado o delineamento experimental inteiramente casualizado com 20 tratamentos (progênie) e três repetições de 20 sementes. O fruto de J. ribifolia é seco, cápsula loculicida e septicida, endocarpo lenhoso e deiscência explosiva (autocórica). A semente é oval, endospérmica, de testa lisa, com diferentes colorações e carúncula presa na parte ventral. O hilo é visível e a rafe bem marcada longitudinalmente. A germinação é hipógea-criptocotiledonar. O tempo médio para germinação foi de 10 a 40 dias. As matrizes de J. ribifolia estudadas apresentaram variabilidade genética significativa para a maioria dos caracteres estudados.
The aim of this study was to estimate genetic parameters of fruits, seeds and seedlings of Jatropha ribifolia (Pohl) Baill, subsidizing future breeding and genetic conservation programs. Twenty matrices of the species and the fruits collected in the Caatinga area in the city of Jequié - BA / Brazil were selected. For morphological description, the features of 50 fruits and 50 seeds were observed. For germination, completely randomized design was used with 20 treatments (progeny) and three replicates of 20 seeds. J. ribifolia fruit is dry and has loculicidal and septicidal capsule, woody endocarp and explosive dehiscence (autochory). The seed is oval, endospermic and has smooth testa and different colors, with caruncle attached to the ventral part. The hilum is visible and the raphe is longitudinally marked. Germination is hypogeal-cryptocotylar. The average time for germination was from 10 to 40 days. The matrices of J. ribifolia showed significant genetic variability for most of the studied traits.
Subject(s)
Seeds/genetics , Jatropha/genetics , Fruit/genetics , Plants, Medicinal/classification , Seedlings/geneticsABSTRACT
Industrial noise can be successfully mitigated with the combined use of passive and active noise control (ANC) strategies. In a noisy area, a practical solution for noise attenuation may include both the use of baffles and ANC. When the operator is required to stay in movement in a delimited spatial area, conventional ANC is usually not able to adequately cancel the noise over the whole area. Control strategies need to be devised to achieve acceptable spatial coverage. A three-dimensional vibration-acoustic model is proposed in this paper. The signal of an accelerometer attached to the bulk of a centrifugal pump installed in an empty room was used as the input of this model. The signal of a microphone that changes its position in a spatial grid inside this room is the output. In the first stage, the ARX models are used to describe a SISO system where the input is the machine vibration and the output is the noise level measured at a certain point. In the second stage, spatial interpolation is used to estimate the model parameters. Results show good agreement between experimental data and model predictions, indicating the potential of using the model for the design of ANC.
Subject(s)
Sweet Syndrome/complications , Takayasu Arteritis/complications , Female , Humans , Middle AgedABSTRACT
The suitability of high resolution, in situ dc-sheet resistance monitoring (SRM) as a simplified and reliable sensing technique towards detection and tracking of protein immobilization has been explored. Non-specific adsorption of bovine serum albumin (BSA) onto a very thin gold film, acting as the sensing resistor, has been employed as a model system. For comparison, the novel sensing method was combined with surface plasmon resonance (SPR) spectroscopy, using the same flow cell and sensing surface. Two different, well known adsorption states, involving a composite layer of irreversibly and reversibly bound BSA, were clearly resolved by both methods. Clearly structured, pronounced and fully reproducible film resistance modulations have been resolved in the associated SRM data. The transition from reversibly bound BSA to the diluted protein phase is associated with an unusually large decrease in the dc-sheet resistance. The observed resistance modulation magnitude for an adsorbed BSA monolayer corresponds to approximately 1%, and up to 100 mOmega at a 10 Omega sensing resistor. The sheet resistance of irreversibly bound BSA was determined to 0.24 kOmega/cm2, and the associated specific resistivity estimated to 1-2x10(4) Omega cm.
Subject(s)
Biosensing Techniques/methods , Coated Materials, Biocompatible/analysis , Electric Impedance , Electrochemistry/methods , Materials Testing/methods , Metals/chemistry , Serum Albumin, Bovine/analysis , Adsorption , Biosensing Techniques/instrumentation , Coated Materials, Biocompatible/chemistry , Electrochemistry/instrumentation , Materials Testing/instrumentation , Microelectrodes , Protein Binding , Reproducibility of Results , Sensitivity and Specificity , Serum Albumin, Bovine/chemistryABSTRACT
PURPOSE: To evaluate safety and usefulness of dipyridamole-radionuclide ventriculography (D-RVG), soon after acute myocardial infarction (MI), in the prediction of future cardiac events. Traditionally performed tests were also compared. PATIENTS AND METHODS: Forty-one patients (4 females) with recent MI underwent rest and dipyridamole (0.58 mg/kg of body weight) radionuclide ventriculography. The criteria for a positive test for ischemia was failure to increase left ventricular ejection fraction in 0.05 from baseline value. All patients had also coronary angiography and 36 patients underwent thallium-201 scintigraphy for comparison. The mean follow-up was 16 +/- 3 months. The following findings were considered future for events: cardiac death, reinfarction, significant angina or heart failure. RESULTS: During the follow-up 18 of the 20 patients who had cardiac events had shown positive dipyridamole-RVG, as opposed to 5 of 21 event-free patients (p less than 0.01). The ventriculographic criteria for a positive test and dipyridamole left ventricular ejection fraction were the strongest predictors of those medical events (p less than 0.01 and p less than 0.001). Among the 36 patients who had thallium-201 imaging, 16 subsequently had cardiac events and the scans were positive in 82% (p less than 0.01). Twelve (29%) patients experienced reactions during dipyridamole infusion although no fatal complications were noted. CONCLUSION: Dipyridamole-RVG is relatively safe and a sensitive predictor of future cardiac events soon after acute MI, although additional experience is required before this new technique should be routinely recommended as an alternative approach.
Subject(s)
Dipyridamole , Myocardial Infarction , Radionuclide Ventriculography , Coronary Angiography , Female , Humans , Male , Prognosis , Prospective Studies , Thallium RadioisotopesABSTRACT
Os autores tecem comentarios a respeito da necessidade de uma sistematizacao no atendimento extra-hospitalar do politraumatizado e, em particular, do traumatizado de torax e do abdome. Enfantizam a necessidade de um melhor treinamento para todos aqueles que se propoem a esse tipo de atendimento, alem das melhorias das ambulancias no tocante a seus recursos terapeuticos disponiveis.Chamam tambem atencao quanto a importancia da comunicacao, em tadas as fases do atendimento, do medico com o setor de emergencia
