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Int J Biol Macromol ; 146: 763-772, 2020 Mar 01.
Article in English | MEDLINE | ID: mdl-31778696

ABSTRACT

N/S-doped carbon supported AgNPs has been synthesized at low-cost, and scalable method using silver complex of chitosan based polymer. The fabricated nanocomposites exhibited excellent electrocatalytic performance as a glucose sensor. Remarkably, the fabricated glucose sensor is exhibited an ultrahigh sensitivity of 35.22 mAmM-1 cm-2 with a very low detection limit (0.046 mM) and long-term durability (30 days). Under optimized conditions, a wide linear response was obtained from 5 µM to 3 mM with an excellent linear response (R2 = 0.9940) was also obtained by AgNPs/NSC modified electrode. The presence of the heteroatom and AgNPs into the carbon matrix greatly enhances the selectivity for glucose over potential interferences in aqueous solution, with interfering agents. Overall, the present methodology demonstrates an efficient, robust, and aqueous-media-tolerable nanocomposite material as an electrochemical sensor and a potential alternative tool for the detection of glucose.


Subject(s)
Biosensing Techniques/methods , Chitosan/chemistry , Electrochemical Techniques/methods , Glucose/analysis , Metal Nanoparticles/chemistry , Nanocomposites/chemistry , Polymers/chemistry , Silver/chemistry , Carbon , Electrochemistry , Electrodes , Formaldehyde/chemistry , Limit of Detection , Reproducibility of Results , Thiourea/chemistry
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