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1.
Aviat Space Environ Med ; 83(5): 504-8, 2012 May.
Article in English | MEDLINE | ID: mdl-22606867

ABSTRACT

BACKGROUND: Airline pilots belong to a relatively high-income, healthy population, with sedentary behavior during their flight activity, who often eat unsuitable meals. We assessed the prevalence of metabolic syndrome (MS) and the levels of high sensitivity C-reactive protein (hs-CRP) in a population of airline pilot in order to study a possible relationship between the hs-CRP and MS. METHODS: MS was established according to the National Cholesterol Education Program, Adult Treatment Panel III. hs-CRP was classified into three categories: Low < 1 mg x L(-1); intermediate: 1-3 mg x L(-1); and high: > 3 mg x L(-1). RESULTS: The prevalence of MS was 14.8%. The hs-CRP level in the population studied was 1.68 +/- 1.79 mg x L(-1). hs-CRP significantly increased with age. The pilots with MS presented significantly higher hs-CRP levels (median = 1.9 with an interquartile range (IQR) = 2.5 mg x L(-1)) than the pilots without MS (median = 0.9 and IQR = 1.275 mg x L(-1)). MS significantly increased in the groups with high hs-CRP in comparison with pilots with intermediate hs-CRP levels and with those with low hs-CRP levels. A similar association was found between the levels of hs-CRP and the prevalence of MS in the three age groups. The levels of hs-CRP increased in pilots as they presented greater numbers of MS diagnostic criteria. DISCUSSION: hs-CRP rises significantly in pilots of increasing age, in pilots with MS as compared to those without the syndrome, and in pilots as they present greater numbers of MS diagnostic criteria. The prevalence of MS increased among the groups with higher levels of hs-CRP.


Subject(s)
C-Reactive Protein/analysis , Metabolic Syndrome/blood , Adult , Aerospace Medicine , Aged , Aging/blood , Cross-Sectional Studies , Humans , Male , Metabolic Syndrome/diagnosis , Middle Aged , Prevalence , Young Adult
2.
Med. segur. trab ; 58(226): 49-58, ene.-mar. 2012. ilus, tab, graf
Article in Spanish | IBECS | ID: ibc-103146

ABSTRACT

Introducción: Ácido úrico sérico y Síndrome Metabólico, son factores que se relacionan fuertemente con enfermedades cardiovasculares. Objetivo: conocer la prevalencia de Síndrome Metabólico así como la concentración de Ácido úrico sérico en una población aeronáutica y determinar qué posibles relaciones muestran unos niveles normales y/o patológicos de Ácido úrico con respecto a la presencia o ausencia de Síndrome Metabólico. Material y métodos: Población de 790 pilotos de líneas aéreas, todos varones. Se siguió el criterio del National Cholesterol Education Program para el diagnóstico de Síndrome Metabólico, pero modificado, utilizándose en lugar de circunferencia cintura el índice de masa corporal. Resultados: El 25,4% de los pilotos presentaron valores elevados de Ácido Úrico. El 19,9% de los pilotos presentó Síndrome Metabólico. El riesgo de presentar Síndrome Metabólico por tener el Ácido úrico elevado frente al riesgo que presentaron los que tienen el Ácido úrico normal (razón de prevalencias) fue de 2,6 con un intervalo de confianza al 95% entre 2 y 3,4 y con una significación de p<0,001. Existe una asociación lineal positiva entre el aumento de la concentración de Ácido úrico y el número de factores diagnósticos positivos de Síndrome Metabólico (p<0,001). Conclusiones: Nuestros resultados sugieren que la hiperuricemia puede ser una complicación relacionada son el propio Síndrome Metabólico; la obesidad abdominal puede condicionar un aumento en la concentración de Ácido úrico. Se hace preciso aumentar los estudios sobre poblaciones aeronáuticas respecto a estos factores metabólicos con objeto de aumentar la seguridad en vuelo (AU)


Fundamentals: Uric acid and metabolic syndrome are strongly related to cardiovascular disease. Objective: To assess the prevalence of metabolic syndrome as well as the levels of uric acid among aircrew members and to determine the relationship between the levels of uric acid and the prevalence of metabolic syndrome. Methods: We studied a population of 790 male airline pilots. We used the definition of metabolic syndrome of the National Cholesterol Education Program Adult Treatment Panel III, but modified by replacing waist circumference for the measurement of body mass index. Results: 25.4% of the pilots presented elevated level of uric acid. 19.9% of pilots presented metabolic syndrome. The risk to present metabolic syndrome in pilots with uric acid elevated in relation to those pilots with normal uric acid was 2.6 higher with a confidence interval of 95% between 2 and 3,4 with a significance of p<0.001. There is a positive linear association between the increased concentration of uric acid and the number of metabolic syndrome diagnostic criteria (p<0,001). Conclusions: Our results suggest that hyperuricemia can be a complication related to the metabolic syndrome. The abdominal obesity may condition an increased concentration of serum uric acid. It is necessary to increase the number of studies on aircrew members in relation to the above mentioned metabolic factors in order to increase the flight safety (AU)


Subject(s)
Humans , Male , Metabolic Syndrome/epidemiology , Uric Acid/blood , Hyperuricemia/epidemiology , Aviation , Body Mass Index , Risk Factors , Obesity, Abdominal/epidemiology
3.
Aviat Space Environ Med ; 78(8): 784-8, 2007 Aug.
Article in English | MEDLINE | ID: mdl-17760286

ABSTRACT

BACKGROUND: Disorders of the spine are common in fighter crewmembers. The high cost of training and experience for pilots makes it important to use all reasonable clinical means to restore grounded pilots to their flying duties, provided that all safety standards are maintained. To date, there has been limited research into specific surgical treatment of spine injury in pilots. This study was designed to examine the efficacy of surgical procedures in Spanish Air Force fighter pilots with injuries to the spine, as well as the aeromedical disposition of such pilots. METHODS: A retrospective study was conducted using the medical records of 14 fighter pilots with symptomatic spinal disorders treated by surgery. RESULTS: The 14 pilots underwent surgery: 12 cases involved fusion of vertebral structures (arthrodesis), while 2 pilots underwent discectomy. All pilots were subsequently given waivers to resume flying duties. DISCUSSION: The successful return to flight status of these pilots indicates the practical application of surgical techniques that safely stabilize the spine. However, due the sample limited size of the sample, further studies are needed.


Subject(s)
Arthrodesis , Diskectomy , Intervertebral Disc Displacement/surgery , Military Personnel , Occupational Diseases/surgery , Adult , Aerospace Medicine , Humans , Intervertebral Disc Displacement/rehabilitation , Occupational Diseases/rehabilitation , Retrospective Studies , Spain , Treatment Outcome
4.
Endocrinol. nutr. (Ed. impr.) ; 53(6): 382-387, jun. 2006. tab
Article in Es | IBECS | ID: ibc-046312

ABSTRACT

Se presenta el caso de una mujer que 5 años después de haber sido diagnosticada de feocromocitoma adrenal derecho e hiperparatiroidismo primario, desarrolló una acromegalia por adenoma hipofisario. Se descartó la existencia de carcinoma medular de tiroides y de mutación germinal en RET y en VHL. La determinación del gen MEN-1 también resultó negativa. Se dan en este caso la existencia de un tumor característico de la NEM-2 como el feocromocitoma, otro característico de la NEM-1 como el adenoma hipofisario secretor de GH e hiperparatiroidismo primario, que se da en ambas neoplasias endocrinas múltiples, pero sin mutaciones germinales en RET, VHL y MEN-1


We present the case of a 56-year-old woman who, 5 years after receiving a diagnosis of unilateral adrenal pheochromocytoma and primary hyperparathyroidism, was diagnosed with acromegaly caused by a growth hormone-secreting pituitary adenoma. No germ-line mutations in RET, VHL and MEN-1 gene were detected. Medullar thyroid carcinoma was also ruled out. Therefore, the present case shows coexistence of a tumor characteristic of MEN 2 syndrome (pheochromocytoma) with a growth hormone-secreting pituitary tumor characteristic of MEN 1 syndrome and primary hyperparathyroidism, which can be observed in both multiple endocrine neoplasia syndromes, but without germ-line mutations in RET, VHL and MEN-1


Subject(s)
Female , Middle Aged , Humans , Acromegaly/complications , Pheochromocytoma/complications , Hyperparathyroidism/complications , Prolactinoma/complications , Multiple Endocrine Neoplasia Type 2a/diagnosis , Multiple Endocrine Neoplasia Type 1/diagnosis , von Hippel-Lindau Disease/diagnosis
5.
Med. aeroesp. ambient ; 4(6): 263-267, jun. 2006. ilus, tab
Article in Es | IBECS | ID: ibc-052019

ABSTRACT

En una población de 762 pilotos de transporte pertenecientes a distintas líneas aéreas españolas se determinó glucemia plasmática basal en ayunas con motivo de su examen físico periódico. De ellos, 604 pilotos (79,3%) presentaron nivel de glucemia basal normal (= 100 y 126 mg/dl) y 8 pilotos (1%) fueron diagnosticados de diabetes mellitus (glucosa >= 126mg/dl), de acuerdo con los últimos criterios de la Asociación Americana de Diabetes (2003). La prevalencia de glucemia basal alterada, condición que predispone al desarrollo de diabetes y constituye un factor de riesgo cardiovascular aumenta con la edad y así de 9,5% en menores de 30 años, pasa a 12,9% en el grupo de 30 a 40 años, a 21,7% en el grupo de 40 a 50 años y a 32,4% en el grupo de más de 50 años. La prevalencia de diabetes mellitus aumenta con la edad y así mientras en menores de 30 años no se detectó ningún caso, en los pilotos de más de 50 años se detectaron 50 casos


In a sample of 762 transport pilots belonging to different Spanish airlines, the fasting plasma glucose was measured at the time of their periodical physical examination. According to last criteria established by the American Diabetes association (2003) 604 pilots (79,3%) presented a normal fasting plasma glucose (=100 y = 126mg/dl). The prevalence of impaired fasting glucose, condition that predisposes to diabetes and cardiovascular disease, increases with aging. In this regard, the prevalence of 9,55 inpilots under 30 years of age, increased to 12,9% in the group with 30 to 40 years of age, to 21,7% in the group of 40 to 50 years and up to 32,4% in pilots with 50 years and older. the prevalence of diabetes als rises with age and while in pilots under 30 years of age no single case of diabetes was detected, 5 cases were found in the group of 50 years and older, accounting for 2,9%


Subject(s)
Male , Adult , Middle Aged , Humans , Hyperglycemia/epidemiology , Diabetes Mellitus, Type 2/epidemiology , Aircraft , Aerospace Medicine
6.
Med. mil ; 56(1): 6-11, ene.-mar. 2000. tab, graf
Article in Es | IBECS | ID: ibc-37442

ABSTRACT

Introducción: La hipoxia es uno de los grandes problemas dentro del mundo aeronáutico. La falta de oxígeno afecta a la capacidad intelectual, psicomotora y estado de alerta del individuo. Las alteraciones pueden ser muy variadas. Esta variabilidad individual dependerá de muchos factores, uno de los factores que podría influir en la respuesta del SNC a los efectos de la deprivación de oxígeno es la edad. Objetivos. El objetivo de este trabajo es estudiar si existen diferencias, respecto a la edad, en la capacidad de actuación y reacción del personal de vuelo, bajo condiciones de hipoxia. Sujetos y métodos: Se estudiaron 161 tripulantes aéreos que realizaron un vuelo de entrenamiento en una cámara de baja presión. Se cuantificó el grado de alteraciones de las funciones cognitivas, mediante un test desarrollado durante un vuelo. Resultados: El grupo de sujetos cuyas edades estaban comprendidas entre 30 y 39 años obtuvieron estadísticamente (p<0,05) mejores resultados en el test que el grupo entre 20-29 años y aunque no es estadísticamente significativo, el primer grupo tiende a una mejor respuesta en el test sobre el grupo de mayores de 40 años. Conclusiones: Los tripulantes aéreos entre 30 y 39 años reúnen las condiciones idóneas de experiencia, por un lado y por otro se encuentran en una edad donde todavía no se ha manifestado el deterioro de las capacidades cognitivas y psicomotoras por el envejecimiento, para tolerar las condiciones de hipoxia (AU)


Subject(s)
Adult , Male , Middle Aged , Humans , Hypoxia/physiopathology , Altitude Sickness/physiopathology , Age Factors , Psychomotor Disorders/etiology , Oxygen Consumption/physiology , Arousal/physiology , Atmospheric Pressure , Aviation , Aerospace Medicine/methods , Atmosphere Exposure Chambers , Tobacco Use Disorder/epidemiology
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