ABSTRACT
Sixteen samples of some Nigerian indigenous beverages and foodstuffs were analyzed for their aflatoxin content. All the eight samples of beverages tested were found to be contaminated with aflatoxin. Of the eight samples of foodstuffs tested, all contained aflatoxin except ewedu, dawadawa and shoko yokoto. All the beverages used as culture media for Aspergillus flavus (UBMI) supported the growth of the fungus and aflatoxin elaboration. A. flavus was found to grow luxuriantly on all samples of foodstuffs, except dawadawa. However, growth of the fungus on foodstuffs was not synonymous with aflatoxin production.
Subject(s)
Aflatoxins/biosynthesis , Aspergillus flavus/metabolism , Beverages/analysis , Food Contamination , Plants, Edible/microbiology , Food Analysis , Food Microbiology , NigeriaSubject(s)
Aflatoxins/pharmacology , Dietary Fats/pharmacology , Lipids/blood , Animals , Cercopithecus , Cholesterol/blood , Haplorhini , Phospholipids/bloodABSTRACT
A single i.p. dose of aflatoxin B1 had no significant effect on the thrombotest clotting times of monkeys subsisting on low-fat and high-fat dietary regimens, respectively. There was a significant interaction between aflatoxin and dietary fat level.
Subject(s)
Aflatoxins/pharmacology , Blood Coagulation/drug effects , Dietary Fats , Thrombin/physiology , Animals , Cercopithecus , HaplorhiniABSTRACT
Aflatoxin B1 significantly depressed serum lipid levels in specimens of Cercopithecus aethiops, Cercopithecus mona, Erythrocebus patas and Papio anubis. Serum cholesterol, total phospholipids and total lipids were not affected to the same extent.
Subject(s)
Aflatoxins/pharmacology , Haplorhini/blood , Lipids/blood , Animals , Cercopithecus/blood , Chlorocebus aethiops/blood , Cholesterol/blood , Erythrocebus patas/blood , Papio/blood , Phospholipids/bloodSubject(s)
Aflatoxins/pharmacology , Blood Coagulation/drug effects , Animals , Body Weight/drug effects , Cercopithecus , Diet , Haplorhini , Time FactorsABSTRACT
The blood clotting time and serum lipid values of newly-captured Nigerian monkeys were determined during the period of adaptation. Large fluctuations in serum free and total cholesterol and phospholipid values were observed throughout the 12-week period of investigation. The variations in blood clotting time were not significant (p greater than 0.05). These wide variations in lipid values suggest the need for caution in interpreting data from newly-captured subhuman primates.
