Efficacy of temporomandibular joint arthrocentesis with and without injection of sodium hyaluronate in treatment of internal derangements.

PURPOSE: This study was designed to investigate the efficacy of arthrocentesis with and without injection of sodium hyaluronate (SH) into the upper joint space in the treatment of temporomandibular joint (TMJ) internal derangements. PATIENTS AND METHODS: Forty-one TMJs in 5 males and 26 females aged 14 to 53 years comprised the study material. The patients' complaints were limited mouth opening, TMJ pain and tenderness, and joint noises during function. Patients were randomly divided into 2 groups in which only arthrocentesis was performed in 1 group and arthrocentesis plus intra-articular injection of sodium hyaluronate was performed in the other group. Both groups contained patients with disc displacement with reduction and with closed lock. Clinical evaluation of the patients was done before the procedure, immediately after the procedure, on postoperative day 1, and at 1, 2, 3, 4, 5, 6, 9, 12, 18, and 24 months postoperatively. Intensity of TMJ pain, jaw function, and clicking sounds in the TMJ were assessed using visual analog scales. Maximal mouth opening and lateral jaw movements also were recorded at each follow-up visit. RESULTS: Both techniques increased maximal mouth opening, lateral movements, and function, while reducing TMJ pain and noise. CONCLUSIONS: Although patients benefitted from both techniques, arthrocentesis with injection of SH seemed to be superior to arthrocentesis alone.

Effect of arthrocentesis and sodium hyaluronate injection on nitrite, nitrate, and thiobarbituric acid-reactive substance levels in the synovial fluid.

OBJECTIVE: To evaluate the effect of arthrocentesis and sodium hyaluronate (SH) injections on nitrite, nitrate, and thiobarbituric acid-reactive substance (TBA-RS) levels in temporomandibular joint internal derangements. STUDY DESIGN: Arthrocentesis was performed on 10 patients, and 15 patients received a supplemental injection of SH after arthrocentesis. All these patients received an SH injection 15 days after the first intervention. The synovial fluid samples were obtained before arthrocentesis on the first appointment and before the SH injection 15 days later. Nitrite and nitrate levels were measured with a highly sensitive and specific chemiluminescence detection method, and the concentration of lipid peroxidation products was assessed by means of the thiobarbituric acid reaction. RESULTS: Symptomatic improvement was seen in both groups. Nitrite, nitrate, and TBA-RS levels only decreased significantly (P <.05) with a supplemental SH injection after arthrocentesis. CONCLUSIONS: Intra-articular injections of SH may reduce nitrite, nitrate, and TBA-RS levels that play a role in the pathogenesis of various temporomandibular disorders.

Disturbances in oral and dental structures in patients with pediatric lymphoma after chemotherapy: a preliminary report.

OBJECTIVE: The purpose of this study was to evaluate the effects of chemotherapy on oral and dental structures and craniofacial growth in 30 survivors of childhood lymphoma. STUDY DESIGN: Eruption status, root malformations, premature apexification, agenesis, crown anomalies, soft tissue abnormalities, gingival and periodontal status, enamel defects and discolorations, and craniofacial growth status of the subjects were documented and compared with findings in 20 healthy children who served as controls. RESULTS: Statistically significant (P < .05) differences between the study and control groups were found for plaque index, enamel hypoplasias, discolorations, and agenesis. CONCLUSIONS: The results of the study suggest that antineoplastic therapy and/or childhood cancer can result in a higher prevalence of various malformations in teeth. Children treated in the early years of their lives displayed the most severe dental defects, suggesting that immature teeth are at a greater risk of developmental disturbances than fully developed teeth.

In vitro corrosion behaviour and microhardness of high-copper amalgams with platinum and indium.

Samples prepared from Luxalloy, GS-80, Permite-C and Logic and polished after 24 h by traditional methods were stored in polypropylene tubes containing phosphate-buffered saline solutions (pH 3.5 and 6.5) and distilled water. The amounts of mercury, silver, tin, copper, zinc, platinum and indium in the test solutions were determined at the first, second, eighth, 52nd and 78th week by atomic absorption spectrometry. At the end of the eighth week the amalgam samples were removed from solutions and evaluated by Rockwell Super Scial Microhardness tester. Statistically significant low amounts of metal ions were measured for Permite-C containing indium and Logic containing platinum. The microhardness test results showed that there were statistically significant increases in the microhardness of Permite-C and Logic. As a result it was shown that the amalgam samples were affected from corrosion conditions to different degrees. Sample of the Logic group that was stored in distilled water, showed smoother surface properties than other amalgam samples containing high copper. However, it was observed that samples of Permite-C group had the smoothest surface properties.

Tissue reaction to three subcutaneously implanted local hemostatic agents.

Soft tissue response to three subcutaneously implanted local hemostatic agents; oxidised regenerated cellulose (Surgicel), gelatin sponge (Spongostan) and collagen sponge (Hemostagen) were evaluated histopathologically 7, 14, 21, 30 and 45 days following their implantation in rats. The results showed that all materials were well tolerated by soft tissues. These materials neither seemed to impair nor contribute to wound healing.

Extracellular alkaline phosphatase activity as a possible marker for wound healing: a preliminary report.

PURPOSE: This study evaluated the use of extracellular alkaline phosphatase activity as a marker of wound healing. MATERIALS AND METHODS: Fifteen 8-week-old Wistar rats, weighing 180 to 220 g and of both sexes, made up the material of this study. Histopathologic aspects of the healing of full-thickness of wounds created on the dorsal skin of these rats were studied by means of alkaline phosphatase (ALP) enzyme histochemistry and routine microscopy. RESULTS: The current study showed an exclusive localization of extracellular ALP activity in the regions of granulation tissue formation. This localization was time related, and decreased as healing progressed. CONCLUSIONS: Although the biologic significance of ALP is still obscure, use of extracellular ALP activity as a simple and reliable histochemical process marker of the skin wound healing is proposed.

Postoperative pain control by single doses of piroxicam administered sublingually and aspirin.

The objective of this study is to evaluate and compare the analgesic efficacy of Piroxicam Fast Dissolving Dosage Formulation (FDDF) administered sublingually either preoperatively or postoperatively with that of aspirin and placebo. Hundred patients, undergoing surgical removal of mandibular third molars were given sublingually either piroxicam FDDF 40 mg or placebo or aspirin 500 mg according to a double blind experimental model. Pain scores and pain relief was recorded hourly for six hours following the operation. Rescue analgesics used during the trial and overall assessment of the drug were recorded at the end of six hours. Scores were evaluated statistically by student t test. Piroxicam FDDF was significantly (p < 0.05) more effective than aspirin and placebo for all variables, and less rescue analgesics were required in patients receiving piroxicam preoperatively. It was concluded that single doses of piroxicam FDDF administered sublingually either preoperatively or postoperatively appeared to be effective analgesic for the control of pain after third molar surgery with no side effects.

Serum alkaline phosphatase, calcium, and phosphate levels following clinical use of natural coral. Case reports.

Measurement of alkaline phosphatase enzymatic activity is the most commonly used serum marker to assess bone formation. In this present study serum alkaline phosphatase, calcium, and phosphate were measured in 12 patients where natural coral was implanted in surgical bony defects. Blood samples were obtained preoperatively which served as control, and at 1, 7, 15, and 30 days. No statistically significant increase in serum alkaline phosphatase, calcium, and phosphate was observed.

Bone reaction to subperiosteally implanted hydroxyapatite/collagen/glycosaminoglycans and coral in the guinea pig.

Tissue reactions and new bone formation at 30, 60, and 90 days after the subperiosteal implantation of hydroxyapatite/collagen/glycosaminoglycans and blocks of coral in 18 guinea pigs were evaluated histologically with the use of polarized light and light microscopy. Animals implanted with coral showed new bone formation at each time interval and resorption of coral was observed. Histopathologic evaluation of hydroxyapatite/collagen/glycosaminoglycans implants revealed no evidence of new bone formation and the hydroxyapatite particles were surrounded by fibrous connective tissue.

Lymphoepithelial cyst.

Lymphoepithelial cyst is thought to arise from the entrapment of salivary epithelium in lymphoid aggregates during embryogenesis. Such lesions are not common. It has been noted that there is a close association between the oral mucosal lymphoid tissue and the secretory ducts of minor salivary glands which is recognized as "Duct-associated lymphoid tissue" (DALT). A case of lymphoepithelial cyst with histologically documented close proximity between the excretory ducts of the minor salivary gland and lymphoid tissue in the cyst wall suggesting a DALT-like structure is presented.

[Role of odontomas on eruption difficulties of permanent teeth and surgical-orthodontical approach]. / Dislerin sürme güçlügünde odontomanin rolü ve cerrahi-ortodontik yakalasim (2 vaka nedeniyle).

In this case report 2 odontoma cases were presented as an example for surgical-orthodontic approach for the eruption difficulties of permanent teeth. In two cases which left central incisors couldn't erupt because of an odontoma. In both cases the odontomas were enucleated with their capsules and treated orthodontically thus the results were discussed.