ABSTRACT
The South African Menopause Society (SAMS) consensus position statement on menopausal hormone therapy (HT) 2014 is a revision of the SAMS Council consensus statement on menopausal HT published in the SAMJ in May 2007. Information presented in the previous statement has been re-evaluated and new evidence has been incorporated. While the recommendations pertaining to HT remain similar to those in the previous statement, the 2014 revision includes a wider range of clinical benefits for HT, the inclusion of non-hormonal alternatives such as selective serotonin reuptake inhibitors and serotonin noradrenaline reuptake inhibitors for the management of vasomotor symptoms, and an appraisal of bioidentical hormones and complementary medicines used for treatment of menopausal symptoms. New preparations that are likely to be more commonly used in the future are also mentioned. The revised statement emphasises that commencing HT during the 'therapeutic window of opportunity' maximises the benefit-to-risk profile of therapy in symptomatic menopausal women.
Subject(s)
Hormones/therapeutic use , Menopause , Societies, Medical , Female , Humans , Postmenopause , Practice Guidelines as Topic , South AfricaABSTRACT
A case of Cushing's syndrome caused by a right adrenal adenoma in a 16-week gravid patient is reported. After right adrenalectomy she was maintained on replacement doses of hydrocortisone, and at 38 weeks' gestation a healthy but small-for-gestational age infant was delivered vaginally.
Subject(s)
Adenoma/complications , Adrenal Gland Neoplasms/complications , Cushing Syndrome/etiology , Pregnancy Complications, Neoplastic , Adrenalectomy , Adult , Cushing Syndrome/surgery , Female , Humans , Pregnancy , Pregnancy Complications, Neoplastic/surgeryABSTRACT
An artificial insemination by donor (AID) service was started in the Infertility Clinic at Groote Schuur Hospital, Cape Town, in response to repeated requests by patients, doctors and social workers. The methods, results of treatment, and reasons for reorganizing the work of the clinic are presented. Future management at the clinic is also outlined. The clinic has been reorganized and work on semen cryopreservation is being carried out by the Andrology Service at Groote Schuur Hospital. A semen bank has also been established. The ethical, religious, legal and genetic aspects of AID are reviewed.
