ABSTRACT
Acute tubular necrosis (ATN) is a serious medical condition characterized by the rapid destruction of renal tubular epithelial cells, resulting in acute kidney injury, given its multifactorial etiologies, which can include nephrotoxic agents, ischemic insults, hypovolemia, and sepsis. We report the case of a young male patient who presented with recurrent worsening kidney function with bland sediment that was confirmed with multiple kidney biopsies as recurrent attacks of ATN of unclear etiology, which did not respond to supportive measures but did respond to steroids.
ABSTRACT
Acute intermittent porphyria (AIP) is an autosomal, dominant, rare metabolic disturbance that results from a defect in the activity of the heme biosynthesis. It has a heterogeneous presentation, making a prompt diagnosis challenging. We report a case of acute intermittent porphyria in a young female who underwent in vitro fertilization (IVF) and presented with recurrent abdominal pain and posterior reversible encephalopathy syndrome (PRES), progressing to acute progressive quadriparesis post-delivery.
ABSTRACT
BACKGROUND: Alzheimer's disease (AD) is a major health problem, which is of increasing concern because of rising yearly incidence and estimated cost. Early diagnosis and treatment is essential to manage AD effectively and improve the outcomes. Inadequate knowledge can delay the diagnosis. General practitioners should play a more effective role in the identification and diagnosis of AD, and medical education is key to solving this issue. OBJECTIVES: This study aimed to assess the knowledge of undergraduate medical students and to identify the factors that influenced their knowledge. METHODS: This study used a quantitative cross-sectional evaluation of 327 Saudi Arabian medical students from the first and final years in Riyadh, Saudi Arabia, who participated in an online survey via email between March and May 2018. Knowledge of AD was assessed using the 12-item AD Knowledge Test for Health Professionals from the University of Alabama at Birmingham (UAB ADKT). General linear models were used to identify the most significant influence on AD knowledge scores. RESULTS: Only 10.73% of first-year and 33.33% of final-year students scored ≥ 50% on the UAB ADKT. Students pursuing specialties related to AD (adult neurology, geriatrics, or psychiatry) and students aged ≥ 27 years had higher scores (P < 0.05). CONCLUSION: Undergraduate medical students lacked proper knowledge of AD, suggesting that improvements in education programs can help. Future studies are needed to assess the quality and effectiveness of AD education in the curriculum of Saudi medical schools.
