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1.
Sci Prog ; 106(4): 368504231213788, 2023.
Article in English | MEDLINE | ID: mdl-38018091

ABSTRACT

The impact of aggressive capitalist approaches on social, economic and planet sustainability is significant. Economic issues such as inflation, energy costs, taxes and interest rates persist and are further exacerbated by global events such as wars, pandemics and environmental disasters. A sustained history of financial crises exposes weaknesses in modern economies. The Great Attrition, with many quitting jobs, adds to concerns. The diversity of the workforce poses new challenges. Transformative approaches are essential to safeguard societies, economies and the planet. In this work, we use big data and machine learning methods to discover multi-perspective parameters for multi-generational labour markets. The parameters for the academic perspective are discovered using 35,000 article abstracts from the Web of Science for the period 1958-2022 and for the professionals' perspective using 57,000 LinkedIn posts from 2022. We discover a total of 28 parameters and categorized them into five macro-parameters, Learning & Skills, Employment Sectors, Consumer Industries, Learning & Employment Issues and Generations-specific Issues. A complete machine learning software tool is developed for data-driven parameter discovery. A variety of quantitative and visualization methods are applied and multiple taxonomies are extracted to explore multi-generational labour markets. A knowledge structure and literature review of multi-generational labour markets using over 100 research articles is provided. It is expected that this work will enhance the theory and practice of artificial intelligence-based methods for knowledge discovery and system parameter discovery to develop autonomous capabilities and systems and promote novel approaches to labour economics and markets, leading to the development of sustainable societies and economies.

2.
J Clin Med ; 12(13)2023 Jun 26.
Article in English | MEDLINE | ID: mdl-37445316

ABSTRACT

Methanol poisoning is a challenging issue due to its inducing acute multiple organ failures, and especially due to a lack of preparedness, available antidotes, and management protocols. The current study presents six cases of methanol poisoning that attended the emergency department of King Abdul Aziz Specialist Hospital, Taif, Saudi Arabia, between March and November 2022. All of the patients suffered from severe metabolic acidosis and visual impairment following the ingestion of homemade alcoholic beverages and colonia. Three patients were comatose, suffered from post-cardiac pulmonary arrest, and, finally, died, while the other three were non-comatose and discharged from the ICU after improvement. Management was based on clinical symptoms and other laboratory findings due to a shortage of methanol level measurement resources. The antidote, fomepizole, was not given to all of the cases due to its deficiency, and ethanol was given only to one patient due to difficulties in administering it without monitoring its concentration. Methanol poisoning and its outbreak provide insights into the dangers of hazardous homemade alcohol and other pharmaceutical preparations that might be adulterated with methanol, particularly to the shortage of suitable diagnostic testing and antidotes in addition to poor resources for management of intoxicated patients in some regions of Saudi Arabia.

3.
Front Mol Biosci ; 10: 1277862, 2023.
Article in English | MEDLINE | ID: mdl-38274098

ABSTRACT

Personalized medicine in cancer treatment aims to treat each individual's cancer tumor uniquely based on the genetic sequence of the cancer patient and is a much more effective approach compared to traditional methods which involve treating each type of cancer in the same, generic manner. However, personalized treatment requires the classification of cancer-related genes once profiled, which is a highly labor-intensive and time-consuming task for pathologists making the adoption of personalized medicine a slow progress worldwide. In this paper, we propose an intelligent multi-class classifier system that uses a combination of Natural Language Processing (NLP) techniques and Machine Learning algorithms to automatically classify clinically actionable genetic mutations using evidence from text-based medical literature. The training data set for the classifier was obtained from the Memorial Sloan Kettering Cancer Center and the Random Forest algorithm was applied with TF-IDF for feature extraction and truncated SVD for dimensionality reduction. The results show that the proposed model outperforms the previous research in terms of accuracy and precision scores, giving an accuracy score of approximately 82%. The system has the potential to revolutionize cancer treatment and lead to significant improvements in cancer therapy.

4.
Biomed Res Int ; 2022: 3372296, 2022.
Article in English | MEDLINE | ID: mdl-36187499

ABSTRACT

Healthcare occupies a central role in sustainable societies and has an undeniable impact on the well-being of individuals. However, over the years, various diseases have adversely affected the growth and sustainability of these societies. Among them, heart disease is escalating rapidly in both economically settled and undeveloped nations and leads to fatalities around the globe. To reduce the death ratio caused by this disease, there is a need for a framework to continuously monitor a patient's heart status, essentially doing early detection and prediction of heart disease. This paper proposes a scalable Machine Learning (ML) and Internet of Things-(IoT-) based three-layer architecture to store and process a large amount of clinical data continuously, which is needed for the early detection and monitoring of heart disease. Layer 1 of the proposed framework is used to collect data from IoT wearable/implanted smart sensor nodes, which includes various physiological measures that have significant impact on the deterioration of heart status. Layer 2 stores and processes the patient data on a local web server using various ML classification algorithms. Finally, Layer 3 is used to store the critical data of patients on the cloud. The doctor and other caregivers can access the patient health conditions via an android application, provide services to the patient, and inhibit him/her from further damage. Various performance evaluation measures such as accuracy, sensitivity, specificity, F1-measure, MCC-score, and ROC curve are used to check the efficiency of our proposed IoT-based heart disease prediction framework. It is anticipated that this system will assist the healthcare sector and the doctors in diagnosing heart patients in the initial phases.


Subject(s)
Heart Diseases , Internet of Things , Delivery of Health Care , Heart Diseases/diagnosis , Humans , Machine Learning , Monitoring, Physiologic
5.
Chemosphere ; 303(Pt 2): 135065, 2022 Sep.
Article in English | MEDLINE | ID: mdl-35618070

ABSTRACT

Environmental distresses linked to heavy metal (HM) impurity in the water received significant attention among research communities. Recently, advancements in industrial sectors like paper industries, mining, non-ferrous metallurgy, electroplating, mineral paint production, etc. have resulted in massive heavy metals in wastewater. In contrast to organic pollutants, HMs are not recyclable and can be simply engrossed by living organisms. Recently, different solutions have been employed for removing HMs from water and wastewater, like membrane filtration, chemical precipitation, adsorption, ion-exchange, flotation, flocculation, etc. Sorption can be considered one of the efficient solutions for eradicating HMs from waste water. With this motivation, this article concentrates on the design of Remora Optimization with Deep Learning Enabled Heavy Metal Sorption Efficiency Prediction (RODL-HMSEP) model onto Biochar. The proposed RODL-HMSEP technique intends to determine the sorption performance of HMs of various biochar features. Initially, the density based clustering (DBSCAN) technique is applied to simulating the features of metal adsorption data and splitting them into clusters of identical features. Besides, deep belief network (DBN) model was employed for prediction and the efficiency of the DBN model is optimally adjusted with utilize of RO technique. The experimental validation of the RODL-HMSEP technique ensured the promising performance of the RODL-HMSEP technique on the prediction of sorption efficiency onto biochar over other methods The experimental validation of the RODL-HMSEP technique ensured the promising performance of the RODL-HMSEP technique on the prediction of sorption efficiency onto biochar over other methods.


Subject(s)
Deep Learning , Metals, Heavy , Water Pollutants, Chemical , Adsorption , Charcoal/chemistry , Metals, Heavy/analysis , Wastewater , Water Pollutants, Chemical/analysis
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