ABSTRACT
Gastrointestinal stromal tumors (GISTs) are considered the most common mesenchymal tumors of the digestive system. However, they make up less than 1% of all GI tumors. GISTs arise from the interstitial cells of Cajal and are commonly found in the stomach and small intestine, and rarely in the colon and esophagus. In this case report, we present a 57-year-old male, a known diabetic, who complained of abdominal pain. He was diagnosed with cholelithiasis and a GIST in the jejunum, which was managed laparoscopically without complications. Most of the time, patients with GIST present with vague symptoms, or sometimes, they are asymptomatic. The most common symptoms are abdominal pain, GI bleeding, and an abdominal mass. These symptoms are usually related to the site of tumor growth, tumor size, and tumor rupture or perforation. Regardless of the tumor location, surgical excision is the gold standard for treating GISTs.
ABSTRACT
Introduction Breast cancer is the leading type of cancer in women globally, contributing significantly to cancer-related deaths. In Saudi Arabia, it ranks as the second most common cancer among women. Studies have highlighted a lack of awareness about breast cancer, negatively impacting breast self-examination practices. The Eastern Province has particularly high incidence rates. Knowledge of risk and protective factors can aid in prevention and early detection. While some studies show good awareness, this research aims to assess women's knowledge and attitudes about breast cancer risk factors and warning signs in the Eastern Province. Methodology This is a cross-sectional study conducted in Saudi Arabia's Eastern Province from June to October 2023 to assess breast cancer awareness among adult females. Data were collected via an online survey. Data were cleaned in MS Excel (Microsoft Corporation, Redmond, Washington) and analyzed in IBM SPSS Statistics for Windows, Version 23 (Released 2015; IBM Corp., Armonk, New York). Results Our study assessed breast cancer awareness in 697 participants in Saudi Arabia's Eastern Province. Most were aged 20-24 years (30.3%), married (49.2%), and Saudi nationals (97.6%), with higher education (59.4%). Significantly, 69.2% received education on breast cancer risk factors/signs. Some had personal breast cancer diagnoses (5.0%), and 31.7% had affected family members. Participants showed good awareness of various risk factors and warning signs. Significant associations were found between nationality, personal breast cancer diagnosis, and knowledge and attitudes about risk factors. Age, marital status, occupation, education on breast cancer, and personal breast cancer diagnosis influenced knowledge and attitudes about warning signs. Conclusion Our study findings indicate generally good awareness of breast cancer risk factors and warning signs among participants. Age, marital status, occupation, education on breast cancer, and personal breast cancer diagnosis influenced knowledge and attitudes about risk factors and warning signs. Educational efforts should target lesser-known risk factors to enhance prevention and early detection.
ABSTRACT
Migraine, a widespread and incapacitating neurological disorder, affects numerous individuals worldwide, causing severe headaches and impairing their quality of life. The interplay of genetic, environmental, and neurovascular factors underlies the pathophysiology of migraine. This report highlights the case of a 25-year-old woman with recurrent, severe headaches, predominantly in the right frontal and temporal regions. She was diagnosed with migraine with aura, a diagnosis supported by her family history. No previous history of seizures was reported. A comprehensive work-up, including neuroimaging, revealed left internal carotid artery hypoplasia with compensatory collateral circulation. The coexistence of severe migraines and left internal carotid artery hypoplasia underscores the complex interrelationship between cerebrovascular anomalies and neurological symptoms. The rarity of this vascular variation emphasizes the need for attentive clinical evaluation and consideration of anatomical deviations in migraine patients. As medical knowledge progresses, further research is essential to unravel the mechanisms connecting vascular anomalies and neurological disorders, ultimately leading to personalized interventions for improved patient outcomes.
ABSTRACT
BACKGROUND: Gynecomastia, defined as a benign proliferation of the breasts in males, is a common pathology of breasts among adolescent males. The root cause behind the condition is the hormonal imbalance between androgens and estrogens at the time of puberty. Different treatment options can be used; however, surgery is the preferred option. The quality of life (QoL) of affected Individuals is usually affected in all aspects. OBJECTIVES: The aim of the study is to assess the QoL of male Saudi patients diagnosed with gynecomastia and their desire to undergo surgical treatment. METHODS: A cross-sectional study was conducted using an Arabic self-administered online questionnaire that targeted males in Saudi Arabia and was distributed throughout the kingdom. RESULTS: A total of 681 participants were involved in this study. Most of the participants were Saudi (n = 607; 90.6%) and married (n = 158; 79%). Approximately, half of the participants were between 18 and 29 years of age (n = 337; 49.5%), while 41.1% and 9.3% were between 30 and 49 years and more than 50 years old, respectively. About 29.5% of the participants were from the middle region, while 26.7% of them were from the northern region, followed by 19.5% of participants from the western region, and only 14.4% and 9.8% from the eastern or southern region. On analysis of different domains, there was no statistically significant difference between participants with gynecomastia and the control group in QoL. CONCLUSIONS: Patients showed no statistically significant change in the QoL between those diagnosed with gynecomastia and those in the control group. Also, more than one-third of our patients did not want to undergo breast reduction surgery.
