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1.
J Pharm Bioallied Sci ; 16(Suppl 2): S1641-S1646, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38882900

ABSTRACT

Electronic cigarettes, frequently referred to as e-cigarettes, have emerged as a controversial and rapidly growing phenomenon in the realm of tobacco and nicotine consumption worldwide. This study reports the prevalence of respiratory symptoms among e-cigarette users. This study also helps to understand the potential harmful effects and importance of quitting e-cigarette smoking. An observational cross-sectional study was carried out in Saudi Arabia. The study period was from September 2022 to August 2023. The sample size was 447 participants. Among recent e-cigarette users in this Saudi study, usage varied, with 44.1% using 1-5 days, 33.6% using 6-30 days, and 22.4% using e-cigarettes previously but not in the previous month. Vape devices were predominant (42.7%). There were significant associations emerged between e-cigarette use frequency and symptoms such as fatigue, breathlessness, and shortness of breath. E-cigarette use was notably linked to asthma-related symptoms, underscoring its concerning impact on respiratory health (P < 0.05). E-cigarette consumption has a significant impact on respiratory effects and specifically asthma-related symptoms among this Saudi population.

2.
Cureus ; 15(5): e39784, 2023 May.
Article in English | MEDLINE | ID: mdl-37398780

ABSTRACT

BACKGROUND: Headaches are a common complaint among asthma patients. However, there is no study to assess the relationship between asthma and headaches or to assess the prevalence of headaches among asthma patients in Saudi Arabia. We aim to study the relationship between asthma and headaches and also to assess the prevalence of headaches among asthma patients. RESEARCH METHODOLOGY: We conducted a cross-sectional study among 528 asthmatic patients. Participants were selected through non-probability sampling from the system of four hospitals (King Fahad Specialist Hospital, King Saud Hospital, Buraidah Central Hospital, and Qassim University Hospital). The duration of our study was one year from 11 September 2022 to 14 May 2023. Data collection was performed by using a pre-tested and self-administered questionnaire. Data were analyzed through IBM SPSS Statistics for Windows, Version 24 (Released 2016; IBM Corp., Armonk, New York, United States) by using the chi-square test to assess the relationship between the qualitative variables and independent t-test and ANOVA for comparing the quantitative variables with a significant level set at p-value < 0.05. RESULTS: Five hundred and twenty-eight asthmatics were studied for demographics, asthma management, and headaches. Most of the patients were male, married, and university-educated. Sixty-one percent had uncontrolled asthma, and 47.3 percent of individuals had headaches, mostly migraines. Uncontrolled asthma was linked to greater headache prevalence. Gender, educational level, and headache type did not affect headache prevalence in demographic and asthma control subgroups. Co-occurring asthma and migraines may benefit from asthma control and treatment. CONCLUSION:  The research emphasizes the significant frequency of uncontrolled asthma and headaches among asthmatic patients. The association between asthma control and headache prevalence was statistically significant, highlighting the necessity for appropriate management and treatment techniques for both disorders. These findings have significant implications for health care providers and politicians seeking to improve the quality of life for those with asthma and co-occurring headaches.

3.
Cureus ; 14(11): e31079, 2022 Nov.
Article in English | MEDLINE | ID: mdl-36475162

ABSTRACT

Objectives This study aimed to assess the general population's knowledge of rheumatoid arthritis (RA), its health consequences, and the impact of mass media on their knowledge and attitudes in Qassim, Saudi Arabia. Methods A cross-sectional study was used through an online questionnaire to determine the general characteristics of participants and the influence of mass media on their knowledge, attitudes, and fears toward RA. An online pretested and standardized questionnaire was distributed through social media using combined convenience and snowball sampling that targeted the general population residing in Qassim, Saudi Arabia, between 10 January and 11 March 2022. Frequencies and percentages were employed as descriptive statistics. To examine the statistical differences in knowledge scores between various sociodemographic factors, the student's t-test and analysis of variance were used. Results A total of 419 participants were included. About 20.3% of the participants were unaware of RA. Mean knowledge showed very low scores of 2.5 ± 2.24 out of 15. There were no significant differences in knowledge when it was compared with different sociodemographic variables, except for marital status and monthly income. There was a positive attitude toward the seriousness of RA. The correlation of knowledge scores with attitude and fear scores showed a poor or negligible correlation (rho= 0.130, p=0.008), whereas, with media influence, there was a low positive correlation (rho= 0.347 p<0.001). Conclusion This study found that even though our sample population had acceptable views concerning the significance of rheumatoid arthritis, their understanding of the condition was lacking. To promote knowledge of RA and its unfavorable health impact on affected individuals, public awareness initiatives with substantial media influence should be implemented.

4.
Cureus ; 14(11): e31530, 2022 Nov.
Article in English | MEDLINE | ID: mdl-36532927

ABSTRACT

Background and objective Basic Life Support (BLS) is critical because it keeps patients with life-threatening illnesses or injuries alive and maintains viability until a team of paramedics or hospital staff can provide expert care. There are many events that can result in serious injury and cause a person to stop breathing. BLS awareness among the population who have relatives with heart diseases greatly increases their confidence to act quickly when necessary and reduces their level of hesitation. In this study, we aimed to evaluate the level of clinical competence in the population who have relatives with heart diseases for them to recognize and respond to individuals in need of BLS in the Qassim region of Saudi Arabia. Methodology We conducted a quantitative, observational, and analytical cross-sectional study to achieve our objective. The targeted population involved only Saudis. The study was conducted electronically using social network apps in the Al-Qassim region of Saudi Arabia. The questionnaire evaluated if the subject had a family member with heart disease. Data collected included sociodemographic characteristics and knowledge and awareness about BLS as related to specific objectives. Results Of the 414 participants, 58.8% were females; 33.3% were between the ages of 40-49 years, and 30.7% were between 18-29 years old. The prevalence of participants who reported participating in cardiopulmonary resuscitation (CPR) training was 19.8%. The main reasons for not participating in these training were a lack of knowledge about the courses (60.5%), being too busy (16.2%), and thinking that they did not need them (12.3%). Being younger than 29 years in age was one of the factors associated with participating in CPR training [odds ratio (OR): 11.85, 95% confidence interval (CI): 1.54-91.42, p=0.017] versus those aged over 59 years. Gender was significantly associated with the rate of participation in CPR training: females had significantly lower rates of participation than males (15.2% vs. 25.7%, OR: 0.52, 95% CI: 0.32-0.84, p=0.008). Of note, 25.5% of the participants had adequate knowledge regarding CPR. Having trained in CPR was significantly associated with a higher level of knowledge among the participants (1.82-fold) (OR: 1.82, 95% CI: 1.08-3.06, p=0.023). Conclusion Based on our findings, there is limited awareness and training related to CPR among people with relatives suffering from cardiac diseases in the Qassim region of Saudi Arabia. This may be associated with higher rates of morbidity and mortality related to heart diseases in the region.

5.
Cureus ; 14(10): e30297, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36407197

ABSTRACT

Objective The study aims to evaluate the primary healthcare practitioner's (PHCP) knowledge, attitude, and practice toward systemic lupus erythematosus (SLE) and to explore the difficulties of early referral to specialized clinics. Method This is a cross-sectional study conducted between February and March 2022 targeting the PHCP among the primary healthcare centers in Qassim, Saudi Arabia. The study was conducted among 203 participants who enrolled via a cluster random sampling technique depending on the survey. Qualitative categorical variables are expressed as frequencies and percentages, while continuous variables are reported as means and standard deviations (SD). The one-way analysis of variance (ANOVA) test and the independent T-test have been used to explore the relationship between participants' knowledge scores and their socio-demographic characteristics. A P-value ≤0.05 was considered statistically significant. Result The study found that only 4.4% of participating PHCPs had good knowledge related to SLE, while 45.8% of them had fair knowledge, and nearly half of them (49.8%) had poor knowledge. It was noted that GPs who specialized in family medicine or saw more than 40 patients each week had comparably better knowledge than others, which was statistically significant (p<0.05). The difficulty in diagnosing SLE patients was mentioned by 48.3% of the PHCPs. Family medicine consultants (p<0.001), those who worked in a tertiary care facility for more than six months (p<0.001) and those who worked in a rheumatology department (p<0.05), reported considerably better levels of comfort when treating SLE patients. Conclusion This study found that included participants' understanding of SLE, its diagnosis, and management was inadequate. Coordination between rheumatologists and experts from many disciplines at the primary, secondary, and tertiary levels of care is critical for overcoming ambiguities and obstacles in the diagnosis and therapy of SLE patients.

6.
Saudi Med J ; 41(6): 652-656, 2020 Jun.
Article in English | MEDLINE | ID: mdl-32518934

ABSTRACT

Immunoglobulin G4-related disease (IgG4-RD) is rare disease entity and has recently been recognized as an inflammatory disorder with the tendency to affect multiple organs. Pachymeningitis of spine caused by IgG4-related disease is extremely rare. Neck pain and spinal cord compression symptoms consist of usual presentation of IgG4-related spinal pachymeningitis; however, polyarthritis is an unusual presentation of this disease, and it was reported in only one case that mimicked psoriatic arthritis. In this report, we describe a case of IgG4-related spinal pachymeningitis in a middle-age male who presented initially with neck pain and  rheumatoid arthritis-like symptoms and later on developed both right upper and lower limb weakness. He was found to had pachymeningeal thickening on a cervical magnetic resonance image (MRI) and elevated serum IgG4 levels. He was treated with glucocorticoids and rituximab, which led to a significantly positive radiological response.


Subject(s)
Immunoglobulin G4-Related Disease/complications , Meningitis/etiology , Adult , Arthritis, Rheumatoid/etiology , Biomarkers/blood , Cervical Vertebrae , Extremities , Glucocorticoids/therapeutic use , Humans , Immunoglobulin G/blood , Magnetic Resonance Imaging , Male , Meningitis/diagnosis , Meningitis/drug therapy , Muscle Weakness/etiology , Neck Pain/etiology , Rituximab/therapeutic use , Spinal Cord Compression/etiology , Treatment Outcome
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