Uricase biofunctionalized plasmonic sensor for uric acid detection with APTES-modified gold nanotopping.

Current uric acid detection methodologies lack the requisite sensitivity and selectivity for point-of-care applications. Plasmonic sensors, while promising, demand refinement for improved performance. This work introduces a biofunctionalized sensor predicated on surface plasmon resonance to quantify uric acid within physiologically relevant concentration ranges. The sensor employs the covalent immobilization of uricase enzyme using 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-Hydroxysuccinimide (NHS) crosslinking agents, ensuring the durable adherence of the enzyme onto the sensor probe. Characterization through atomic force microscopy and Fourier transform infrared spectroscopy validate surface alterations. The Langmuir adsorption isotherm model elucidates binding kinetics, revealing a sensor binding affinity of 298.83 (mg/dL)-1, and a maximum adsorption capacity of approximately 1.0751°. The biofunctionalized sensor exhibits a sensitivity of 0.0755°/(mg/dL), a linear correlation coefficient of 0.8313, and a limit of detection of 0.095 mg/dL. Selectivity tests against potentially competing interferents like glucose, ascorbic acid, urea, D-cystine, and creatinine showcase a significant resonance angle shift of 1.1135° for uric acid compared to 0.1853° for interferents at the same concentration. Significantly, at a low uric acid concentration of 0.5 mg/dL, a distinct shift of 0.3706° was observed, setting it apart from the lower values noticed at higher concentrations for all typical interferent samples. The uricase enzyme significantly enhances plasmonic sensors for uric acid detection, showcasing a seamless integration of optical principles and biological recognition elements. These sensors hold promise as vital tools in clinical and point-of-care settings, offering transformative potential in biosensing technologies and the potential to revolutionize healthcare outcomes in biomedicine.

Miniaturized Broadband Bi-Yagi Antenna Array for Ambient RF Energy Harvesting.

This paper presents a miniaturized broadband Bi-Yagi antenna array that covers a bandwidth from 1.79 GHz to 2.56 GHz. The proposed antenna achieves a tradeoff between maximizing bandwidth, effective area, and gain while minimizing physical dimensions. The antenna design considers the coupling between the radiator and director elements, resulting in increased bandwidth as the resonating modes shift apart. Additionally, the proposed design optimizes element spacing and dimensions to achieve high gain, wide bandwidth, efficient radiation, and a minimum aperture size. The proposed antenna, with physical dimensions of 138.6 mm × 47.7 mm × 1.57 mm, demonstrates gains ranging from 6.2 dBi to 9.34 dBi across the frequency range, with a total efficiency between 88% and 98%. The proposed design is experimentally validated by measuring the reflection coefficients, input impedance, gain, and normalized radiation pattern. These features make the antenna well suited for capturing and harvesting electromagnetic waves in mobile wireless and Wi-Fi applications.

A High-Performance Circularly Polarized and Harmonic Rejection Rectenna for Electromagnetic Energy Harvesting.

This paper presents a novel circularly polarized rectenna designed for efficient electromagnetic energy harvesting at the 2.45 GHz ISM band. A compact antenna structure is designed to achieve high performance in terms of radiation efficiency, axial ratio, directivity, effective area, and harmonic rejection over the entire bandwidth of the ISM frequency band. The optimized rectifier circuit enhances the RF harvested energy efficiency, with an AC-to-DC conversion efficiency ranging from 36% to 70% for low-level input power ranging from -10 dBm to 0 dBm. The stable output of DC power confirms the suitability of this design for various practical applications, including wireless sensor networks, energy harvesting power supplies, medical implants, and environmental monitoring systems. Experimental validation, which includes both the reflection coefficient and radiation patterns of the designed antenna, confirms the accuracy of the simulation. The study found that the proposed energy harvesting system has a high total efficiency ranging from 53% to 63% and is well-suited for low-power energy harvesting (0 dBm) from ambient electromagnetic radiation. The proposed circularly polarized rectenna is a competitive option for efficient electromagnetic energy harvesting, both as a standalone unit and in an array, due to its high performance, feasibility, and versatility in meeting various energy harvesting requirements. This makes it a promising and cost-effective solution for various wireless communication applications, offering great potential for efficient energy harvesting from ambient electromagnetic radiation.

Assessment of Silicone Rubber/Lead Oxide Composites Enriched with Bi2O3, WO3, BaO, and SnO2 Nanoparticles for Radiation Shielding Applications.

This study aimed to prepare silicone rubber composites with heavy metal oxide nanoparticles for gamma ray shielding applications. Different heavy metal oxide nanoparticles were incorporated into the silicone rubber matrix, and the prepared composites were characterized for their thermal, mechanical, and radiation shielding properties. The density of the prepared SR samples ranged from 1.25 to 2.611 g·cm-3, with SR-2 having the highest density due to the presence of lead oxide. Additionally, the thermal stability of the materials improved with the addition of HMO nanoparticles, as indicated by TGA results. The prepared SR materials showed ultimate deformation displacement ranging from 14.17 to 21.23 mm, with the highest value recorded for SR-3 and the lowest for SR-2. We investigated the transmission factor (TF) of gamma rays through silicone rubber (SR) composites with different heavy metal oxide (HMO) nanoparticles. The addition of HMOs resulted in a decrease in TF values, indicating improved radiation shielding performance. The TF was found to be lowest in SR-5, which contained 15% of Bi2O3, WO3, BaO, and Zr2O3 each. The linear attenuation coefficient (LAC) of the SR samples was also evaluated, and it was found that the incorporation of HMOs increased the probability of photon interactions, leading to improved radiation protection effectiveness. The half-value layer (HVL) of the SR samples was also examined, and it was found that the addition of HMOs resulted in a significant reduction in HVL values, particularly at low energy levels. SR-5 had the lowest HVL among the group, while SR-2, SR-3, and SR-4 had higher HVL values. These results demonstrate the effectiveness of using HMOs in enhancing the radiation shielding properties of SR composites, particularly for low-energy gamma rays.

Mechanical, Morphological, Thermal and the Attenuation Properties of Heavy Mortars Doped with Nanoparticles for Gamma-Ray Shielding Applications.

This study aimed to develop a mortar composite with improved gamma ray shielding properties using WO3 and Bi2O3 nanoparticles, as well as granite residue as a partial replacement of sand. The physical properties and effects of sand substitution and nanoparticle addition on the mortar composite were analyzed. TEM analysis confirmed the size of Bi2O3 and WO3 NPs to be 40 ± 5 nm and 35 ± 2 nm, respectively. SEM images showed that increasing the percentage of granite residues and nanoparticles improved the homogeneity of the mixture and decreased the percentage of voids. TGA analysis indicated that the thermal properties of the material improved with the increase in nanoparticles, without decreasing the material weight at higher temperatures. The linear attenuation coefficients were reported and we found that the LAC value at 0.06 MeV increases by a factor of 2.47 when adding Bi2O3, while it is enhanced by a factor of 1.12 at 0.662 MeV. From the LAC data, the incorporation of Bi2O3 nanoparticles can greatly affect the LAC at low energies, and still have a small but noticeable effect at higher energies. The addition of Bi2O3 nanoparticles into the mortars led to a decrease in the half value layer, resulting in excellent shielding properties against gamma rays. The mean free path of the mortars was found to increase with increasing photon energy, but the addition of Bi2O3 led to a decrease in MFP and better attenuation, making the CGN-20 mortar the most ideal in terms of shielding ability among the prepared mortars. Our findings on the improved gamma ray shielding properties of the developed mortar composite have promising implications for radiation shielding applications and granite waste recycling.