Nanoarchitectonics of molecular self assembled monolayers by transition metal ion intercalation for enhancement of molecular junction conductivity.

This research delves into the role of metal ions in enhancing the electronic properties of 5,5'-bis(mercaptomethyl)-2,2'-bipyridine (BPD) self-assembled monolayers (SAMs). It combines experimental techniques and numerical simulations to understand the impact of these ions on the structural, electronic, and transport properties of BPD SAMs. Key findings include the varied bonding preferences of metal ions and their significant role in modifying the electronic structure of BPD molecules, leading to enhanced electron delocalization and migration. The study highlights the potential of metal ions in advancing molecular electronics, particularly in the development of high-performance electronic and energy devices.

IMPROVEMENT OF THE MODEL OF PREVENTION OF MALIGNANT NEOPLASM OF THE GASTRIC.

The fight against malignant neoplasms is one of the most important problems of health care in Ukraine; its relevance is due to the continuous growth of oncological morbidity in the population, the complexity of timely diagnosis and treatment, high cost, as well as quite high levels of disability and mortality of such patients. Gastric cancer, which remains one of the most common and deadly neoplasms in the world, occupies one of the leading positions among cancer. Aim - scientifically substantiate and develop a model for improving the organization of prevention of malignant neoplasms of the gastric. A study of performance indicators of oncology health care facilities and a survey of respondents was conducted: 180 respondents of patients with gastric cancer and precancerous diseases of the stomach using medical-statistical, sociological methods and questionnaires. A functional and organizational model for improving the prevention of malignant neoplasms of the stomach has been scientifically substantiated and developed. The features of the proposed model were the inclusion in it, in addition to the previously existing, innovative elements (an algorithm for early diagnosis and prevention of negative consequences of malignant neoplasms of the stomach at the level of primary medical care, reminders for primary medical care doctors regarding monitoring of risk factors and predictors of malignancy of precancerous stomach diseases, the allocation of a dynamic monitoring group due to the increased risk of precancerous gastric diseases becoming oncological), as well as previously existing, but functionally changed components (optimization of the functions of the primary care physician in relation to the information provision of the patient and his relatives; monitoring of risk factors for precancerous and cancerous stomach diseases, control and accounting for the implementation of the recommendations of specialist doctors and rehabilitation specialists), the interaction between which provided the model with a qualitatively new focus on achieving its strategic goal - preventing the occurrence and progression of the development of malignant neoplasms of the gastric. The proposed functional and organizational model will lead to a positive medical and social effect for the improvement of the organization of the prevention of gastric cancer in the main areas: systematicity, comprehensiveness and preventive direction. Its implementation will lead to an increase in early detection, coverage of dynamic monitoring of patients, as well as a projected economic effect due to a decrease in the specific weight of neglected forms of gastric cancer, improvement in survival and reduction in mortality.

ORGANIZATIONAL AND FUNCTIONAL MODEL OF IMPROVEMENT OF THE SYSTEM OF PREVENTION OF CONFLICT SITUATIONS IN THE FIELD OF HEALTHCARE.

In order for any organization, including a medical one, to function effectively in modern conditions, the entire management system, including the human resources management system, needs constant development and improvement. The staff of health care institutions is a community of people with different levels of conflict. The ability to build constructive relationships, use the most effective strategies of behavior in conflict situations and resolve conflict contradictions is an important indicator of the effectiveness of the work of managers at all levels.The aim - to substantiate, develop and implement in the health care system a functional and organizational model of conflict prevention in medical organizations.582 medical workers of primary care centers and hospitals of the Chernivtsi region were involved in the study, who passed an individual survey about conflict situations in medical institutions and, applying a systemic analysis, developed a functional and organizational model for the prevention of conflict situations in the field of medicine.One of the most important functions of medical managers, doctors and secondary medical personnel in medical institutions is to ensure a balance between rights and obligations in the triad «administration - medical worker - patient¼. This function is implemented thanks to control over the creation of regulatory documents and analysis of the work of direct performers. To resolve conflict situations and disagreements that arise directly between the manager and medical workers regarding «acute¼ issues, we suggest using a general conflict management algorithm in a medical organization. Directly to improve the system of prevention of conflict situations in the field of health care, an organizational and functional model has been developed, the basis of which is the correction of pre-conflict situations and their exacerbation.The functional-organizational model of prevention of conflict situations in medical organizations developed in the course of the study reflects modern trends in health care and allows a medical worker to predict the further aggravation of conflict situations or resolve an existing conflict in a non-conflict way.

A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies.

Intermolecular cross-linking through electron irradiation is proven to be an effective tool to improve the mechanical and electronic properties of molecular self-assembled monolayers (SAMs), which is known to be a key player for material nanoarchitectonics. Here we study the effect of electron irradiation on the electronic transport properties of aromatic 5,5'-bis(mercaptomethyl)-2,2'-bipyridine (BPD; HS-CH2-(C5H3N)2-CH2-SH) and electron saturated 1-dodecanethiol (C12; CH3-(CH2)11-SH) molecules self-assembled on an Au (111) surface. We could not create any successful junctions for transport measurements for the electron irradiated C12 SAMs due the deterioration of such molecules with electron saturated nature. For the aromatic molecules, the electron bombardment results in significant reduction of the current despite the electron irradiation-induced intermolecular cross-linking, which should create extra transport channels for charge carriers. The current rectification also reduces after the electron bombardment. In order to interpret the experimental results and give right diagnostics behind the decrease of the current through the junction after electron irradiation, we supplement the experiment with quantum transport calculations using Green's functional formalism in combination with density functional theory. The simulation results show that the reduced current after electron irradiation can be related to the detachment of the molecules from the gold substrate and reattachment to other molecules. The formation of diamond-like structures due to intermolecular-cross linking can also be the reason for the reduced current obtained in the experiments. We have also considered the case when the BPD molecules get broken-conjugated due to the attachment of extra hydrogen atoms to the carbon backbone of the molecule. This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.